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conflicts of interest: the genesis of synthetic antimalarial agents in peace and war.malaria has had an enormous impact on human history, not least in times of war. the disease has been treatable by a natural remedy, quinine, since the 17th century, but the production of synthetic antimalarial agents was first achieved in germany in the wake of the great war of 1914-1918, in which malaria had caused immense problems. in the 1920s research workers in the bayer laboratories of the ig farbenindustrie consortium developed the 8-aminoquinoline plasmoquine (the forerunner of primaquin ...19958626269
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