| canine visceral leishmaniasis on margarita island (nueva esparta, venezuela). | the frequency of american visceral leishmaniasis affecting humans on margarita island, venezuela, has increased in recent years, and infected dogs appear to constitute the principal source of infection. elisa tests with leishmania donovani promastigotes and rk39 antigen from l. chagasi in serum from 541 dogs were positive in 33.1% and 21.6% of the samples, respectively. a second blood sample taken from 50 animals after 8-10 months revealed an increase from 24% to 40% of elisa positivity to both ... | 2000 | 11132371 |
| epidemiological and immunological aspects of human visceral leishmaniasis on margarita island, venezuela. | sixty-five patients were diagnosed with visceral leishmaniasis (vl) on margarita island in the decade from 1990 to1999; 86.2% were <= 3 years old. all were leishmanin-negative at diagnosis. evaluation of 23 cured patients in 1999 revealed that 22/23 had converted to leishmanin-positive; five had persisting antibodies to rk39 antigen, with no clinical evidence of disease. leishmanin tests were positive in 20.2% of 1,643 healthy individuals from 417 households in endemic areas. of the positive rea ... | 2003 | 12563469 |