| identification of an immunodominant 40 kda merozoite antigen common to the australian t and dixie vaccine strains of babesia bovis and the development of diagnostic tests specific for these strains. | antigenic differences among australian vaccine and field strains of babesia bovis were investigated in an attempt to identify strain specific antigens. immunoblots revealed substantial differences between the current vaccine strains, designated t and dixie, and previous vaccine strains and field isolates collected on properties where vaccination with the t or dixie strains had failed to provide complete protection against tick-borne challenge. a major difference was an immunodominant 40 kda anti ... | 1995 | 8747906 |
| investigations of breakdowns in protection provided by living babesia bovis vaccine. | field investigations of protection afforded by live babesia bovis vaccine in australia revealed that a ninefold increase in vaccine failures occurred in the period from 1985 to 1990. laboratory trials using 189 experimental cattle were conducted to evaluate the protection afforded by the babesia bovis strain used in the commercial vaccine during this time. four isolates from clinical cases of babesiosis in vaccinated cattle were assessed. the results showed that the strain used in the vaccine du ... | 1992 | 1496802 |
| studies on failure of t strain live babesia bovis vaccine. | field investigations of the protection afforded by the australian live babesia bovis vaccine used in the early 1990s (t strain) revealed inadequate vaccine-induced protection in certain herds. vaccination/challenge trials using 207 experimental cattle were conducted to evaluate the protection afforded by t strain b bovis against field isolates from these herds. the trials investigated whether isolates that could 'break-through' t strain immunity were present in the field, the ability or inabilit ... | 1995 | 8579560 |