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the multi-epitope polypeptide approach in hiv-1 vaccine development.the application of a preventive hiv vaccine is the only hope for most developing countries to halt the aids pandemic. a project aimed to develop a preventive aids vaccine is being carried out since 1992 by three cuban research institutions: centro de ingeniería genética y biotecnologia de la habana, instituto de medicina tropical 'pedro kouri' and laboratorio de investigaciones de sida de la habana. the project includes two main strategies: (a) generation of recombinant multi-epitope polypeptide ...199910596755
dual infection with dengue virus 3 and human immunodeficiency virus 1 in havana, cuba.although dengue virus (den) endemic regions overlap with human immunodeficiency virus 1 (hiv) high incidence areas, little has been documented on hiv and den mixed infection. here we report den/hiv concurrent infections recorded during the den-3 epidemic in 2001-2002 in havana. serologic-confirmed den is described in two hiv-infected subjects with dengue fever symptoms. although patients had dengue disease, the cd4+ cells remained within normal levels and no accelerated progression of hiv diseas ...200919759497
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