| evidence against breast-feeding as a mechanism for vertical transmission of hepatitis b. | a follow-up study of 147 babies born to mothers known to be carriers of hepatitis b surface antigen (hbsag) revealed no evidence for a relationship between breast-feeding and the subsequent development of antigenaemia in the babies. all babies were tested at three or more months of age, and the mean age at last follow-up was eleven months with a mean of three serum specimens per baby (not counting cord-blood specimens). the frequency of acquisition of hbsag and anti-hbs was almost identical amon ... | 1975 | 52772 |
| geographical distribution of the subtype of hepatitis b surface antigen in chinese. | using the much more sensitive hemagglutination inhibition assay for subtyping of hepatitis b surface antigen (hbsag), we examined the determinants a, d, w and r in 192 from 228 hbsag positive adults who had been found after screening with reversed passive hemagglutination method. sixty-four subtypable cases were asymptomatic carriers and the remaining 128 were liver disease patients. among them there was no significant difference of the subtypes, invariably with adw as the main subtype. geograph ... | 1977 | 196971 |
| seroepidemiology of hepatitis b virus, hepatitis d virus, and human immunodeficiency virus infections among parenteral drug abusers in southern taiwan. | a total of 390 parenteral drug abusers (pdas) at the kaohsiung municipal narcotics abstention institute were examined for markers of hepatitis b virus (hbv), hepatitis d virus (hdv), and human immunodeficiency virus (hiv). all sera were tested for hepatitis b surface antigen (hbsag), surface antibody (anti-hbs), and core antibody (anti-hbc) by radioimmunoassay (ria) and for antibody to hiv (anti-hiv) by enzyme-linked immunosorbent assay (elisa). hepatitis b e antigen (hbeag) and antibody to hdv ... | 1989 | 2778445 |
| effects of gb virus-c/hepatitis g virus on hepatitis b and c viremia in multiple hepatitis virus infections. | we found that patients with dual hbv and gbv-c/hgv infection had comparable serum hbv dna positivity and mean virus concentration compared with age-matched hbv carriers, and those with triple infection had a significantly lower hbv dna positivity. serum hcv rna positivity and mean virus titer were similar between hcv carriers with or without gbv-c/hgv co-infection, and those with gbv-c/hgv co-infection seemed to have a lower serum alt level. these data suggest that gbv-c/hgv infection exerts no ... | 1998 | 9638149 |
| identification and characterization of a prevalent hepatitis b virus x protein mutant in taiwanese patients with hepatocellular carcinoma. | the aim of this study was to investigate whether there was a particular hepatitis b virus (hbv) x protein (hbx) mutant associated with taiwanese patients with hepatocellular carcinoma (hcc). initially, the entire coding region of hbx gene from the serum samples of 14 taiwanese patients were sequenced. a novel mutant, hbx-a31, was preferentially found in patients with hcc. sera from 67 patients with hcc and 100 patients with chronic hepatitis b were thus subjected for codon 31 analysis using a du ... | 2000 | 11077437 |
| tt virus infection in screened taiwanese blood donors. | tt virus (ttv) is a newly discovered human dna virus of uncertain clinical significance. the aim of this study was to determine the prevalence of ttv infection among blood donors in taiwan. | 2000 | 11155069 |
| habitual betel quid chewing as a risk factor for cirrhosis: a case-control study. | betel quid chewing, part of traditional taiwanese culture, is common in 10%-20% of the human population worldwide. in this case-control study we assessed the independent and interactive role of habitual betel quid chewing and chronic hepatitis b virus (hbv) and hepatitis c virus (hcv) infection on risk of cirrhosis. subjects enrolled included 210 pairs of sex- and age-matched cirrhotic patients and healthy controls. information on risk factors was obtained through serologic examination of hepati ... | 2003 | 14530785 |
| sen and hepatitis virus infections in nontransfused children and pediatric thalassemia patients with multiple transfusions in taiwan. | southern taiwan is a hepatitis b and c viruses (hbv, hcv) endemic area. sen virus (senv) infection has been suggested as transfusion-related hepatitis. two variants of senv (senv-d and senv-h) have been studied in non-transfused children and transfusion-dependent thalassemia patients. | 2007 | 17341855 |
| increased risk of viral hepatitis in taiwanese male conscriptees with tattoos. | a number of previous literature reviews and research studies have found a correlation between viral hepatitis infections and tattoos. the 1897 subjects of the current study were young adult male military recruits in southern taiwan (476 with tattoos and 1421 without tattoos) who underwent induction physical examinations before conscription. during the examination, blood samples were collected to screen for hepatitis b surface antigen, antibodies to hepatitis c virus (anti-hepatitis b hcv), syphi ... | 2007 | 17521106 |
| long-term tracking of hepatitis b viral load and the relationship with risk for hepatocellular carcinoma in men. | little is known about the longitudinal course of hepatitis b virus (hbv) load and its relationship with the development of hepatocellular carcinoma (hcc). we conducted a case-cohort study nested within a cohort of 2874 hbv surface antigen-positive male taiwanese government employees aged 30 years or older. hbv genotype and dna levels (i.e. viral load) were tested using polymerase chain reaction-based assays on plasma samples from 112 cases and 1031 non-cases. prediagnostic plasma levels of hbv d ... | 2008 | 17999990 |
| the oncogenic potential of hepatitis b virus rta181t/ surface truncation mutant. | previously, a less prevalent lamivudine-resistant mutant (rta181t) was discovered in taiwanese patients, in which a stop codon in the surface gene concomitantly occurred, leading to impaired secretion of hepatitis b virus (hbv) surface antigen. the rta181t mutant also conferred drug resistance to adefovir. we discovered a 39-year-old patient with advanced hepatocellular carcionoma, who was seropositive for hbv e antigen but seronegative for hbv surface antigen. nucleotide sequence analysis revea ... | 2008 | 19043921 |
| molecular epidemiology of hepatitis d virus infection among injecting drug users with and without human immunodeficiency virus infection in taiwan. | an outbreak of human immunodeficiency virus (hiv) infection occurred among injecting drug users (idu) in taiwan between 2003 and 2006, when an extremely high prevalence of hepatitis c virus (hcv) infection was also detected. to determine whether clusters of hepatitis d virus (hdv) infection occurred in this outbreak, 4 groups of subjects were studied: group 1, hiv-infected idu (n = 904); group 2, hiv-infected non-idu (n = 880); group 3, hiv-uninfected idu (n = 211); and group 4, hiv-uninfected n ... | 2010 | 21191061 |
| natural history of chronic hepatitis b revealed. | chronic hepatitis b is a worldwide public health challenge. knowledge of natural history of chronic hepatitis b is important for the management of the disease. a community-based prospective cohort study was carried out to evaluate the risk predictors of progression of chronic hepatitis b in taiwan. a total of 23,820 participants were enrolled in 1991-1992 from seven townships in taiwan. their serum samples were collected at study entry and tested for hepatitis b surface antigen (hbsag) and e ant ... | 2011 | 21323729 |