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[analysis of antibodies against human immunodeficiency virus on a voluntary basis in healthy persons in amsterdam 1988 and 1989].at the municipal health service of amsterdam it is possible to be tested for hiv antibodies after signing an informed consent. in 1988, 1247 persons were tested (797 men, 450 women) and in 1989, 1400 persons (869 men, 531 women). fifty-eight persons were identified as hiv-seropositive for the first time (1988: 24 men, 3 women; 1989: 28 men, 3 women). all but one woman belonged to a risk group or had had sexual contact with a person from a known risk group. in 1989 no increase in the percentage o ...19902215729
prevalence of human t-cell leukemia virus antibody among heterosexuals living in amsterdam, the netherlands.to determine the heterosexual spread of human t-cell leukemia virus (htlv-i) infections, a cohort of 472 individuals with more than 5 heterosexual partners in the 6 months before entry was studied. they were recruited from visitors to the clinic for sexually transmitted diseases of the municipal health service. half of the study group was born in the netherlands, 13% in surinam or the dutch antilles, and 8% in turkey or morocco. seventy percent were involved in commercial sex. three persons were ...19902280259
circulation of hiv antigen in blood according to stage of infection, risk group, age and geographic origin.human immunodeficiency virus antigen (hiv-ag) was determined by enzyme immunoassay (eia) in hiv-antibody (anti-hiv) positive as well as pre-anti-hiv seroconversion sera and the results analysed according to stage of infection, risk group, age and geographic origin. eleven (19%) of 58 homosexual men tested showed hiv-ag in a serum taken 3-4 months before or one at the time of anti-hiv seroconversion. in another eight (14%) hiv-ag persisted after seroconversion and half of them developed aids or a ...19873428375
risk factors for the transition from noninjection to injection drug use and accompanying aids risk behavior in a cohort of drug users.although injection drug users have been shown to reduce high-risk injection behaviors in response to the epidemic of human immunodeficiency virus (hiv) infection and acquired immunodeficiency syndrome (aids), the total elimination of risk behaviors has not been achieved. a more fundamental preventive measure may be to keep drug users from starting to inject at all. the authors selected 184 drug users from a cohort study in amsterdam, the netherlands, from 1985 to 1992, who had reported at entry ...19948209874
re: "determinants of hiv disease progression among homosexual men registered in the tricontinental seroconverter study" and "progression of human immunodeficiency virus type 1 (hiv-1) infection among homosexual men in hepatitis b vaccine trial cohorts in amsterdam, new york city, and san francisco, 1978-1991". 19968610669
predictors of mortality in the amsterdam cohort of human immunodeficiency virus (hiv)-positive and hiv-negative drug users.the impact of human immunodeficiency virus (hiv) infection and other risk factors on mortality was studied in a cohort of dutch injection drug users and drug users who did not inject. participants were recruited between 1985 and 1992 and followed up through 1993. vital status was ascertained through repeat visit information, supplemented by population register data. a total of 77 deaths were recorded among 632 drug users, for a mortality rate per 1,000 person-years of 7 for hiv-negative noninjec ...19968633622
[post-exposure treatment against hiv outside of the hospital in amsterdam, january-december 2000].the infectious diseases department of the amsterdam public health service regularly sees people who have possibly been exposed to human body fluids infected with hepatitis b virus (hbv), hepatitis c virus (hcv) or human immunodeficiency virus (hiv), as a result of incidents in either a non-hospital-related occupation or during their leisure time. until january 2000, people reporting possible exposure were referred to hospitals for hiv post-exposure prophylaxis (hiv-pep), whereas for hbv and hcv, ...200211957386
risk factors for human herpesvirus 8 infection in a cohort of drug users in the netherlands, 1985-1996.to elucidate the mode of human herpesvirus 8 (hhv-8) transmission in a population of amsterdam drug users, hhv-8 seroprevalence and seroincidence were determined in 1179 drug users in the amsterdam cohort studies (1985-1996). risk factors for hhv-8 infection were examined. serum samples were screened with an enzyme immunoassay by using hhv-8 lytic capsid (open-reading frame [orf] 65) and latent nuclear (orf73) antigens; positive results were confirmed by western blot and immunofluorescence assay ...200212085330
increase in hcv incidence among men who have sex with men in amsterdam most likely caused by sexual transmission.we retrospectively screened 1836 men who have sex with men (msm) participating in the amsterdam cohort studies (1984-2003) for hepatitis c virus (hcv) antibodies. hcv incidence was 0.18/100 person-years (py) in human immunodeficiency virus (hiv)-positive msm (8/4408 py [95% confidence interval {ci}, 0.08-0.36]) but was 0/100 py in msm without hiv (0/7807 py [95% ci, 0.00-0.05]). after 2000, hcv incidence among hiv-positive men increased 10-fold to 0.87/100 py (5/572 py [95% ci, 0.28-2.03]). addi ...200717570110
rise in seroprevalence of herpes simplex virus type 1 among highly sexual active homosexual men and an increasing association between herpes simplex virus type 2 and hiv over time (1984-2003).herpes simplex virus type 1 and type 2 (hsv-1 and hsv-2) are both highly prevalent. the rate of genital hsv-1 transmission is reportedly increasing over time. hsv-2 is considered to be an important risk factor for hiv transmission. we therefore studied changes in the hsv-1 and hsv-2 prevalence in a large cohort of men who have sex with men (msm) over a 20-year time period.200717929177
high prevalence of neutralizing activity against multiple unrelated human immunodeficiency virus type 1 (hiv-1) subtype b variants in sera from hiv-1 subtype b-infected individuals: evidence for subtype-specific rather than strain-specific neutralizing activity.it is assumed that an effective human immunodeficiency virus type 1 (hiv-1) vaccine should be capable of eliciting neutralizing antibodies. however, even the best antibodies known to date lack neutralizing ability against a significant proportion of primary hiv-1 variants and, despite great efforts, still no immunogen is available that can elicit humoral immunity which is protective against infection or disease progression. we tested sera from 35 participants in the amsterdam cohort studies on h ...201019793903
absence of hiv-1 superinfection 1 year after infection between 1985 and 1997 coincides with a reduction in sexual risk behavior in the seroincident amsterdam cohort of homosexual men.incidence rates of human immunodeficiency virus type 1 (hiv-1) superinfection differ among cohorts and, as yet, only 2 cohorts of homosexual men have been screened. here, we investigated the incidence of hiv-1 superinfection during the first year after infection among homosexual participants in the amsterdam cohort studies on hiv infection and aids who seroconverted between 1985 and 1997.201020367230
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