| randomized controlled trial of human papillomavirus testing versus pap cytology in the primary screening for cervical cancer precursors: design, methods and preliminary accrual results of the canadian cervical cancer screening trial (cccast). | since infection with oncogenic human papillomavirus (hpv) has been considered a necessary cause of cervical cancer, tests for oncogenic hpv types have been proposed as adjuncts or replacements to pap cytology. we designed the canadian cervical cancer screening trial (cccast) to compare the relative efficacy of hpv dna testing and pap cytology in primary screening for cervical cancer and its high-grade precursors. cccast randomized women aged 30-69 years in montreal (quebec) and in st. john's (ne ... | 2006 | 16572425 |