Publications

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contribution of hiv-1 infection to acquisition of sexually transmitted disease: a 10-year prospective study.sexually transmitted diseases (stds) enhance human immunodeficiency virus (hiv)-1 susceptibility, but few studies have examined the reciprocal effect of hiv-1 on std acquisition.200415633091
effectiveness of haemophilus influenzae type b conjugate vaccine introduction into routine childhood immunization in kenya.haemophilus influenzae type b (hib) conjugate vaccine is not perceived as a public health priority in africa because data on hib disease burden and vaccine effectiveness are scarce. hib immunization was introduced in kenyan infants in 2001.200616896110
hormonal contraception, sexually transmitted diseases, and risk of heterosexual transmission of human immunodeficiency virus type 1.to examine associations between method of contraception, sexually transmitted diseases (stds), and incident human immunodeficiency virus type 1 (hiv-1) infection, a prospective observational cohort study was done among female sex workers attending a municipal std clinic in mombasa, kenya. demographic and behavioral factors significantly associated with hiv-1 infection included type of workplace, condom use, and parity. in multivariate models, vulvitis, genital ulcer disease, vaginal discharge, a ...19989806034
human immunodeficiency virus infection in long-distance truck drivers in east africa.a cross-sectional survey was performed to determine the seroprevalence and correlates of human immunodeficiency virus (hiv) infection among long-distance truck drivers in kenya.19948002691
long distance truck-drivers: 1. prevalence of sexually transmitted diseases (stds).a cross section study was conducted among long distance truck drivers to determine the prevalence of sexually transmitted diseases (stds) and antibodies to human immunodeficiency virus (hiv). a total of 8 drivers and their assistants en route from port of mombasa to countries in east and central africa were enrolled into the study. blood was taken for hiv and syphilis serology. discharges from urethra and genital ulcer disease (gud) were cultured. seroprevalence for hiv was 18% and 4.6% for syph ...19911752221
impact of smear microscopy results and observed therapy on tuberculosis treatment in mombasa, kenya.tuberculosis (tb) treatment center at coast provincial general hospital in mombasa, kenya.201122118174
virus load during primary human immunodeficiency virus (hiv) type 1 infection is related to the severity of acute hiv illness in kenyan women.we evaluated the association between the severity of primary human immunodeficiency virus type 1 (hiv-1) illness and hiv-1 plasma virus load before seroconversion using stored plasma samples obtained from 74 prostitutes in mombasa, kenya. fever, vomiting, headache, fatigue, arthralgia, myalgia, sore throat, skin rash, or being too sick to work were each associated with significantly higher virus loads before hiv-1 seroconversion, and each additional symptom or sign was associated with an increas ...200212060878
vaginal lactobacilli, microbial flora, and risk of human immunodeficiency virus type 1 and sexually transmitted disease acquisition.a prospective cohort study was conducted to examine the relationship between vaginal colonization with lactobacilli, bacterial vaginosis (bv), and acquisition of human immunodeficiency virus type 1 (hiv-1) and sexually transmitted diseases in a population of sex workers in mombasa, kenya. in total, 657 hiv-1-seronegative women were enrolled and followed at monthly intervals. at baseline, only 26% of women were colonized with lactobacillus species. during follow-up, absence of vaginal lactobacill ...199910558942
genetic analysis of human immunodeficiency virus type 1 strains in kenya: a comparison using phylogenetic analysis and a combinatorial melting assay.we surveyed human immunodeficiency virus (hiv) subtype distribution from peripheral blood mononuclear cells (pbmcs) collected in 1995 from 24 hiv-1-infected kenyan residents (specimens from predominantly male truck drivers and female sex workers near mombasa and nairobi). processed lysates from the pbmc samples were used for env amplification, directly sequenced, and analyzed by phylogenetic analysis. envelope amplification products were also used for analysis in a polymerase chain reaction (pcr ...199910082116
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