| human papillomavirus types 16 and 33, herpes simplex virus type 2 and other risk factors for cervical cancer in sichuan province, china. | cancer of the cervix is relatively common in china, but has been investigated epidemiologically in only a few studies. in the hospital-based case-control study reported here, we investigated the role of various lifestyle and dietary factors, as well as infection with human papillomavirus (hpv) types 16 and 33 and herpes simplex virus type 2 in the aetiology of invasive cervical cancer. the study was conducted in sichuan province, and involved 101 cases with histologically-confirmed cervical canc ... | 1991 | 1848537 |
| analysis of mutations in the urr and e6/e7 oncogenes of hpv 16 cervical cancer isolates from central china. | high rates of cervical cancer have been reported from parts of china and this may reflect a predominance of cervical infection with particularly aggressive human papillomavirus (hpv) variants. this pcr-based investigation of cervical tumours from sichuan province in central china demonstrated an hpv positivity rate of 88%. hpv 16 was most common (21/34, 61%), followed by hpv 18 (3/34, 9%), while types 33, 45, 58 and 59 were each identified in one specimen. sequencing of up to 1349 bases of the 2 ... | 2000 | 10797293 |
| human papillomavirus infection and loss of heterozygosity in esophageal squamous cell carcinoma. | the incidence/mortality rates of esophageal squamous cell carcinoma (escc) vary widely in different parts of china. human papillomavirus (hpv) infection is considered a possible risk factor. loss of heterozygosity (loh) analysis on 87 escc specimens collected from three different areas of china showed lower frequency of loh at marker d3s1621 in linxian, an area with exceptionally high incidence of escc but low hpv infection rate. hpv-positive escc from hong kong, but not sichuan, had higher freq ... | 2004 | 15327839 |
| evaluation of high-risk human papillomaviruses type distribution in cervical cancer in sichuan province of china. | infection with high-risk human papillomavirus is an important factor associated with cervical cancer, and the distribution of hpv types varies greatly worldwide. determination of type-specific hpv prevalence constitutes an important step towards the development of vaccines for the prevention of cervical cancer. | 2008 | 18644159 |
| variation of human papillomavirus 16 in cervical and lung cancers in sichuan, china. | although the crucial role of human papillomaviruses (hpvs), especially hpv-16 in various cancers has been confirmed, the variation of hpv-16 among different cancers have not been investigated in a specific geographic location. in order to elucidate whether similar hpv-16 variants are involved in different kinds of cancers in the same geographic location, the analysis of sequence variants of e6 and e7 oncogenes and l1 gene of hpv-16 in cervical and lung cancers in sichuan, china, was carried out. ... | 2010 | 21175246 |