| association of high hiv-1 rna levels and homozygosity at hla class ii drb1 in adults coinfected with mycobacterium tuberculosis in harare, zimbabwe. | hiv-1 mrna levels (virus load) were quantified for 191 pulmonary tuberculosis (tb) patients and 132 hiv-1 seropositive controls. human leukocyte antigen (hla) class i and ii genes were typed for 188 patients and 121 hiv-1 seropositive controls. the mean log virus load was higher among cases than hiv-1 seropositive controls (p < 0.0001). among the controls, mean log virus load was higher among males than females (p = 0.04). there was no association between virus load and homozygosity at hla class ... | 2002 | 12392855 |
| high rates of clustering of strains causing tuberculosis in harare, zimbabwe: a molecular epidemiological study. | we examined the pattern of tuberculosis (tb) transmission (i.e., reactivation versus recent transmission) and the impact of human immunodeficiency virus (hiv) infection in harare, zimbabwe. consecutive adult smear-positive pulmonary tb patients presenting to an urban hospital in harare were enrolled. a detailed epidemiological questionnaire was completed, and tests for hiv type 1 and cd4 cell counts were performed for each patient. molecular fingerprinting of the genomic dna recovered from cultu ... | 2004 | 15472306 |