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disseminated tuberculosis in the acquired immunodeficiency syndrome era.to assess the influence of human immunodeficiency virus type 1 (hiv)-induced immunodeficiency on the clinical, radiographic, and pathologic features of disseminated tuberculosis (tb), we studied 79 patients presenting in 1984 through 1987 with miliary or focal disseminated disease due to mycobacterium tuberculosis, as well as 4 additional non-hiv patients diagnosed after 1987. clinically defined acquired immunodeficiency syndrome (aids) or aids-related complex (arc) was present in 51 (group 1). ...19911952449
the incidence and epidemiology of human immunodeficiency virus infection in 320 patients treated in an inner-city hemodialysis center.from january 1, 1986 through june 30, 1989, 320 maintenance hemodialysis patients treated at the brookdale hospital medical center were tested for the presence of antibody to the human immunodeficiency virus (hiv) using the enzyme-linked immunosorbent assay (elisa) and western blot assays. thirty-nine patients (12%) tested positive for hiv antibody (hiv+) with both the elisa and western blot, 24 (62%) of whom were known intravenous drug abusers (ivda). of the remaining non-ivda patients, unantic ...19902368703
transmission of multidrug-resistant tuberculosis in a large urban setting.multidrug resistance has become an increasingly important problem in the control and prevention of tuberculosis in large urban centers. although several small outbreaks of multidrug-resistant (mdr) tuberculosis in new york city have been reported, the increase in the number of cases is not fully explained by these recognized outbreaks, and the modes of transmission have not been clearly delineated. transmission patterns of mdr tuberculosis in new york city, therefore, were studied by stratifying ...19957599845
tuberculosis in new york city--turning the tide.from 1978 through 1992, the number of patients with tuberculosis in new york city nearly tripled, and the proportion of such patients who had drug-resistant isolates of mycobacterium tuberculosis more than doubled.19957791840
drug-resistant tuberculosis: etiology, management and prevention.drug-resistant mycobacterium tuberculosis inevitably arises from inadequate or inappropriate drug taking or drug prescribing, effectively resulting in monotherapy. this may occur in the patient being treated (acquired resistance) or in a patient who has been infected by another patient with drug resistant tuberculosis (primary resistance). there is some evidence that multidrug-resistant tuberculosis, ie, resistance to both isoniazid and rifampin, is increasing in the united states and in other c ...19947973169
transmission of tuberculosis in new york city. an analysis by dna fingerprinting and conventional epidemiologic methods.the incidence of tuberculosis and drug resistance is increasing in the united states, but it is not clear how much of the increase is due to reactivation of latent infection and how much to recent transmission.19947993412
transmission of multidrug-resistant mycobacterium tuberculosis among persons with human immunodeficiency virus infection in an urban hospital: epidemiologic and restriction fragment length polymorphism analysis.from january 1990 to december 1991, 16 patients with multidrug-resistant tuberculosis (mdr-tb) caused by mycobacterium tuberculosis resistant to isoniazid, rifampin, and streptomycin were diagnosed at elmhurst hospital. compared with other tb patients, mdr-tb patients were more likely to have human immunodeficiency virus (hiv) infection (14/16 vs. 21/204, p < .001) and a prior admission (10/16 vs. 3/204, p < .001). hiv-infected patients hospitalized for > 10 days within three rooms of an infecti ...19938104226
tuberculosis infection in human immunodeficiency virus-positive adolescents and young adults: a new york city cohort.adolescents with human immunodeficiency virus (hiv) infection are at increased risk for tuberculosis (tb), underscoring the importance of early identification of tb infection. the goals of this study were to assess the factors associated with the completion of evaluations for tb in a cohort of hiv-positive adolescents and young adults and to describe the prevalence of mycobacterium tuberculosis infection and adherence to antituberculous treatment regimens.19968584377
the molecular epidemiology of tuberculosis in new york city: the importance of nosocomial transmission and laboratory error.during the 1980s, new york city experienced a rapid increase of tuberculosis cases, more than 40% of which were human immunodeficiency virus (hiv)-associated.19968959143
a continuing survey of drug-resistant tuberculosis, new york city, april 1994.a 1991 survey showed high levels of drug resistance among tuberculosis patients in new york, ny. as a result, the tuberculosis control program was strengthened, including expanded use of directly observed therapy and improved infection control.19979066457
rifampin-monoresistant tuberculosis in new york city, 1993-1994.all new york city patients whose cultures yielded mycobacterium tuberculosis with isolated resistance to rifampin in 1993 and 1994 were included in this study. of the 96 patients, 48 (50%) had primary resistance, 32 (33%) had acquired resistance, and 16 (17%) had unclassified resistance; 66% had histories of illicit drug use, and 79% were infected with human immunodeficiency virus (hiv). the median time to emergence of resistance was 40 weeks among the 32 patients with acquired resistance. each ...19979431396
risk factors and outcome of human immunodeficiency virus-infected patients with sporadic multidrug-resistant tuberculosis in new york city.an 880 bed university teaching hospital in new york city.19979432387
identification of a w variant outbreak of mycobacterium tuberculosis via population-based molecular epidemiology.typing of mycobacterium tuberculosis could provide a more sensitive means of identifying outbreaks than use of conventional surveillance techniques alone. variants of the new york city w strain of m tuberculosis were identified in new jersey.199910612319
relapse in persons treated for drug-susceptible tuberculosis in a population with high coinfection with human immunodeficiency virus in new york city.the optimal duration of tuberculosis treatment for persons infected with human immunodeficiency virus (hiv) has been debated. a cohort of 4571 culture-positive drug-susceptible patients who received > or =24 weeks of standard 4-drug tuberculosis treatment were assessed to determine the incidence of tuberculosis relapse. tuberculosis "recurrence" was defined as having a positive culture < 30 days after the last treatment date and "relapse" as having a positive culture > or =30 days after the last ...200111595988
persistence of a highly resistant strain of tuberculosis in new york city during 1990-1999.one multidrug-resistant mycobacterium tuberculosis (mdrtb) strain, strain w, caused several nosocomial outbreaks in new york city (nyc) during 1 january 1990-31 july 1993. we reviewed all mdrtb cases verified during 1 august 1993-31 december 1999 that had isolates with either this dna pattern or a variant of this strain, and we compared them to the outbreak cases. of 427 dna-confirmed cases from 1990-1999, 161 (37%) were from 1 august 1993-31 december 1999; these 161 cases, from 56 hospitals and ...200312870116
investigation of sudden death from mycobacterium tuberculosis in a foreign-born worker at a resort hotel.a 60 year-old man born in central america died suddenly in the hallway of his residence on the grounds of a resort hotel where he worked as a dishwasher. the dishwashing station was in a large, poorly ventilated area where a substantial number of food service workers (cooks, wait staff, bus persons, dishwashers, supervisors, etc.) shared air space with the index patient. several social contacts of the patient reported that he had been coughing for many months before his death. the county departm ...200415454912
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