| increasing outpatient fluoroquinolone exposure before tuberculosis diagnosis and impact on culture-negative disease. | fluoroquinolones are widely used to treat routine bacterial infections, but they are also potential first-line antituberculosis agents. empirical fluoroquinolone therapy can delay the diagnosis of tuberculosis and cause resistance in mycobacterium tuberculosis. rates of fluoroquinolone exposure before tuberculosis diagnosis and the impact of fluoroquinolones on culture-negative tuberculosis have not been previously reported. | 2007 | 18039990 |
| mini epidemic of isoniazide resistant tb in rural tn: a need for supervised preventive therapy. | with the resurgence of tuberculosis (tb) in the late 1980s, multi-drug-resistant tb (mdr-tb) also became a serious challenge to the tb control programs across the united states (us). while the incidence of tb resumed a downward trend in the mid 1900s, drug-resistant tb continues to be a national and international problem. we reviewed the public health data of drug-resistant tb cases (1996-2002) in greene county, tn, with a detailed analysis of their contact investigation. our study included demo ... | 2009 | 19691201 |
| elephant-to-human transmission of tuberculosis, 2009. | in 2009, the tennessee department of health received reports of 5 tuberculin skin test (tst) conversions among employees of an elephant refuge and isolation of mycobacterium tuberculosis from a resident elephant. to determine the extent of the outbreak and identify risk factors for tst conversion, we conducted a cohort study and onsite assessment. risk for conversion was increased for elephant caregivers and administrative employees working in the barn housing the m. tuberculosis-infected elepha ... | 2011 | 21392425 |
| chronic lung disease and hiv infection are risk factors for recurrent tuberculosis in a low-incidence setting. | programmatic data from the united states on tuberculosis (tb) recurrence are limited. | 2011 | 21682963 |