| not to wake a sleeping giant: new insights into host-pathogen interactions identify new targets for vaccination against latent mycobacterium tuberculosis infection. | mycobacterium tuberculosis is one of the worlds' most successful and sophisticated pathogens. it is estimated that over 2 billion people today harbour latent m. tuberculosis infection without any clinical symptoms. as most new cases of active tuberculosis (tb) arise from this (growing) number of latently infected individuals, urgent measures to control tb reactivation are required, including post-exposure/therapeutic vaccines. the current bacille calmette-guérin (bcg) vaccine and all new generat ... | 2008 | 18953716 |