| [a short history of anti-rheumatic therapy. ii. aspirin]. | the discovery of aspirin, an antipyretic, anti-inflammatory and analgesic drug, undoubtedly represents a milestone in the history of medical therapy. since ancient times the derivatives of willow (salix alba) were used to treat a variety of fevers and pain syndromes, although the first report dates back to 1763 when the english reverend edward stone described the effect of an extract of the bark willow in treating malaria. in the xix century many apothecaries and chemists, including the italian ... | 2010 | 20657891 |