| preparation of high-titred antisera for sigma virus strains from hawaii and france and their use in neutralization tests in vitro and in vivo. | antisera were prepared in rabbits against two strains of sigma virus, from france and hawaii respectively, using purified virus from cell cultures. all antisera had the same titre by immunofluorescence, 1/400 or 1/800, whether tested against the homologous or the heterologous virus. an antiserum prepared with the french strain neutralized the hawaiian virus at a dilution of 1/800 both in vitro and in vivo. the hawaiian virus was not neutralized to a significant extent by reference mouse ascitic ... | 1988 | 3144993 |