| frequency of spontaneous congenital defects in rhesus and cynomolgus macaques. | this paper summarizes the spontaneous incidence of congenital defects in the rhesus and cynomolgus macaque colonies (macaca mulatta and m. fascicularis) at the california regional primate research center. the computerized database used in this analysis included fetuses, term infants, juveniles, and adults that underwent a necropsy procedure over a 14-year period (1983-1996). the calculated malformation rates were 0.9% (40/4,390) and 0.3% (3/965) for the rhesus and cynomolgus monkey, respectively ... | 1997 | 9437266 |
| the complete genome and genetic characteristics of srv-4 isolated from cynomolgus monkeys (macaca fascicularis). | at least 5 serotypes of exogenous simian retrovirus type d (srv/d) have been found in nonhuman primates, but only srv-1, 2 and 3 have been completely sequenced. srv-4 was recovered once from cynomolgus macaques in california in 1984, but its genome sequences are unknown. here we report the second identification of srv-4 and its complete genome from infected cynomolgus macaques with indochinese and indonesian/indochinese mixed ancestry. phylogenetic analysis demonstrated that srv-4 was distantly ... | 2010 | 20615522 |
| a large-scale snp-based genomic admixture analysis of the captive rhesus macaque colony at the california national primate research center. | some breeding facilities in the united states have crossbred chinese and indian rhesus macaque (macaca mulatta) founders either purposefully or inadvertently. genetic variation that reflects geographic origins among research subjects has the potential to influence experimental outcomes. the use of animals from different geographic regions, their hybrids, and animals of varying degrees of kinship in an experiment can obscure treatment effects under study because high interanimal genetic variance ... | 2012 | 24436199 |