Publications

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periodic mass treatment with diethylcarbamazine for the control of filariasis in american samoa.filariasis surveys made during 1962-63 in 5 villages in american samoa among persons over 5 years of age gave an elephantiasis rate of 3.4%, a microfilarial rate of 26% and a median microfilarial rate (mfd(50)) of 29. these rates were somewhat higher than those found in surveys made in the same villages among villagers of the same ages some 20 years previously. a mass treatment programme with diethylcarbamazine was then decided on.preliminary treatment with a single total regimen of 72 mg of the ...19704396819
analysis of the wuchereria bancrofti population in the people of american samoa.recent interest in mathematical descriptions of the epidemiology of helminth parasites has prompted several attempts to obtain quantitative estimates of reproduction and survival at all stages in their life-histories. the availability of microfilarial counts, repeated on many people over 4(1/2) years, suggested that these estimates could be made for wuchereria bancrofti. important values that were calculated are the duration of patency for single infections (2(1/2) years), the maximum density of ...19685302292
assessing transmission of lymphatic filariasis using parasitologic, serologic, and entomologic tools after mass drug administration in american samoa.assessing the interruption of lymphatic filariasis transmission after annual mass drug administration (mda) requires a better understanding of how to interpret results obtained with the available diagnostic tools. we conducted parasitologic, serologic, and entomologic surveys in three villages in american samoa after sentinel site surveys suggested filarial antigen prevalence was < 1% after five annual mdas with diethylcarbamazine and albendazole. antigen and antifilarial antibody prevalence ran ...200919407122
xenomonitoring of wuchereria bancrofti and dirofilaria immitis infections in mosquitoes from american samoa: trapping considerations and a comparison of polymerase chain reaction assays with dissection.entomologic monitoring of filarial infections, xenomonitoring, may have advantages in certain epidemiologic situations to assess the presence of infections in humans. hemalum staining and dissection and polymerase chain reaction (pcr) were compared to determine the filarial infection status of aedes (stegomyia) mosquitoes in american samoa. the overall prevalences of wuchereria bancrofti and dirofilaria immitis infections in ae. polynesiensis were, respectively, 0.16% and 1.06% by dissection and ...200919407123
impact of five annual rounds of mass drug administration with diethylcarbamazine and albendazole on wuchereria bancrofti infection in american samoa.american samoa began a territory-wide mass drug administration (mda) program with diethylcarbamazine and albendazole in 2000 after baseline surveys indicated that 16.5% of 2,989 residents were infected with wuchereria bancrofti based on tests for circulating filarial antigen. follow-up surveys were conducted in 2001, 2003, and 2006, using convenience samples of residents of sentinel villages. antigenemia prevalence in 2001 (11.5%) and 2003 (13.5%) showed no change. after the 2003 sentinel assess ...200818541771
filariasis in american samoa. iii. studies on chemotherapy against the non-periodic form of wuchereria bancrofti. 195313040683
microfilaria prevalence of diurnally subperiodic wuchereria bancrofti among people having a medical checkup in american samoa in the past 17 years.the yearly change of microfilaria (mf) prevalence rates from 1974 to 1990 was studied in american samoa with people who had medical checkups. the mf rates were found to have been kept at a low level (0.8-2.6%) in the past 17 years. the continued low prevalence reduced clinical filariasis significantly in the past 8 years. the low level of endemicity, despite very close communication with neighbouring western samoa where filariasis is much more prevalent, could be explained by the urbanized livin ...19938459485
improving community participation to eliminate lymphatic filariasis in american samoa.in 2000, the american samoa department of health initiated a campaign of annual mass drug administration (mda) with albendazole and diethylcarbamazine (dec) to eliminate transmission of filariasis. drug coverage was well below prescribed targets in the first three campaigns, ranging from 24 to 52% of the total population. evaluation findings from a variety of formative research methods identified opportunities to improve mda coverage and ensuing program modifications resulted in increased drug c ...201020932818
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