Publications

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efficacy of five annual single doses of diethylcarbamazine for treatment of lymphatic filariasis in fiji.annual single-dose treatments with diethylcarbamazine citrate (dec) at a dose of 6 mg/kg have been reported effective in reducing microfilariae (mf) rate and density and applicable to large-scale filariasis control campaigns. however, the efficacy of such treatments has not been studied quantitatively in relation to different pretreatment levels of endemicity. this study of 32 villages in fiji revealed that five treatments repeated annually steadily reduced village mf rate, and that the degree o ...199810191553
frequency distribution of lymphatic filariasis microfilariae in human populations: population processes and statistical estimation.this paper uses simple mathematical models and statistical estimation techniques to analyse the frequency distribution of microfilariae (mf) in blood samples from human populations which are endemic for lymphatic filariasis. the theoretical analysis examines the relationship between microfilarial burdens and the prevalence of adult (macrofilarial) worms in the human host population. the main finding is that a large proportion of observed mf-negatives may be 'true' zeros, arising from the absence ...19902092297
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