| retrospective analysis of the impact of hiv infection and alcohol use on chronic hepatitis c in a large cohort of drug users. | this retrospective study aimed to better define the respective biological and pathological impact of human immunodeficiency virus infection and chronic alcohol consumption on the course of hepatitis c virus infection in intravenous drug users. | 1998 | 9672168 |
| phylogenetic analyses confirm the high prevalence of hepatitis c virus (hcv) type 4 in the seine-saint-denis district (france) and indicate seven different hcv-4 subtypes linked to two different epidemiological patterns. | hepatitis c virus (hcv) has been classified into six clades as a result of high genetic variability. in the seine-saint-denis district of north-east paris, the prevalence of hcv-4, which usually infects populations from africa or the middle east, is twice as high as that recorded for the whole of continental france (10.2 versus 4.5%). although the pathogenicity of hcv-4 remains unknown, resistance of hcv-4 to therapy appears to be similar to that observed for hcv-1. in order to characterize the ... | 2001 | 11297675 |
| [prevalence of hbv and hcv infections and incidence of hcv infection after 3, 6 and 12 months detention in la santé prison, paris]. | the concentration of a marginal population (35% drug addicts) in prisons necessitates systematic and rigorous screening for hepatitis b and hepatitis c in subjects at risk. in june 1998, a screening program was initiated to determine the prevalence of hbv and hbc infections in prisoners and to determine the incidence after 3, 6 and 12 months detention. the screening program was proposed to 900 prisoners in a paris prison (maison d'arrêt de paris-la santé) from june 3 to november 10, 1998. the pr ... | 2001 | 11965092 |
| risks factors of liver fibrosis in a cohort of intravenous drug users coinfected with hiv and hcv in the haart era: the role of mixed steatosis. | factors associated with the occurrence of severe liver fibrosis in hiv/hcv (hepatitis c virus) coinfected patients remain poorly understood. we thus questioned which factors influenced the occurrence of fibrosis in a cohort of hiv/hcv coinfected intravenous drug user patients. hiv/hcv coinfected intravenous drug user patients naive of anti-hcv therapy for whom a liver biopsy was performed between 1996 and 2003 were retrospectively studied in three university hospitals in paris and the parisian r ... | 2007 | 18166860 |
| [treatment of hepatitis c: advances and consensus]. | | 2002 | 12180308 |
| a randomized trial of ribavirin and interferon-alpha vs. interferon-alpha alone in patients with chronic hepatitis c who were non-responders to a previous treatment. multicenter study group under the coordination of the necker hospital, paris, france. | fifty percent of patients infected with hepatitis c virus (hcv) show no response to alpha-interferon, and no alternative therapy has thus far proven to be effective. therapeutic combination with ribavirin and alpha-interferon has shown promising results in naive patients and in relapsers, but based on limited series, it was reported to be inefficient in non-responders. the aim of our study was therefore to explore and compare, in a randomized trial, the tolerance and potential efficacy of alpha- ... | 1999 | 10424277 |
| transmission of hepatitis c virus in allografted patients: use of viral genotyping as an epidemiological marker. | one hundred and ninety-two allografted patients were tested for hepatitis c virus (hcv) rna from 1992 to 1995 in saint-louis hospital (paris). they received blood products and intravenous immunoglobulins (ivig) and more particularly gammagard ivig suspected of transmitting hcv (batches distributed in france between january 1993 and february 1994). the presence of serum hcv rna was tested by polymerase chain reaction (pcr) in 86 patients who received gammagard ivig during the critical period and ... | 1996 | 8971383 |
| hepatitis c virus (hcv) genotype analysis in apparently healthy anti-hcv-positive parisian blood donors. | as only a few studies have examined the prevalence of various hepatitis c virus (hcv) subtypes in blood donors, information about the variability and route of infection in apparently healthy persons is limited. | 1996 | 8669089 |
| [anti-hcv and hemoglobinopathies]. | | 1990 | 2177601 |
| [anti-hvc antibodies and recipients of blood products: preliminary results of a prospective survey performed at a parisian c. h. u]. | | 1990 | 2177600 |
| [treatment of hepatitis c. paris 27-28 february 2002]. | | 2002 | 12598833 |