Publications

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prevalence of hepatitis c virus antibodies in sydney blood donors.to determine the prevalence of hepatitis c virus (hcv) antibodies in the sydney blood donor population.19921279363
risk factors for hepatitis c virus infection in blood donors: a case-control study.to investigate risk factors for hepatitis c virus (hcv) infection in sydney blood donors.19921279364
prediction of hepatitis c virus infectivity in seropositive australian blood donors by supplemental immunoassays and detection of viral rna.the prevalence of anti-hepatitis c virus (hcv) enzyme immunoassay (eia)-positive in 167,511 australian volunteer blood donors from adelaide, melbourne, perth, and sydney was 0.78%. one thousand two-hundred and eighteen eia-positive serum samples were assessed by supplemental tests including a blocking eia and two peptide eias corresponding to major epitopes of the hcv c-100-3 antigen. seven hundred and eighteen samples (59%) were negative by supplemental testing; no evidence of reactivity with o ...19911657250
post-transfusion hepatitis revisited.to evaluate the risk of post-transfusion and postoperative non-a non-b hepatitis in australia immediately before the introduction of screening for hepatitis c.19957542359
haemophilia a management in victorian, new south wales and south australian haemophilia centres.to examine the management of haemophilia a in australia and to compare it with international trends.19957791641
spread of bloodborne viruses among australian prison entrants.to assess spread of bloodborne viruses among prison entrants in victoria, australia.19957866168
hepatitis c prevalence among australian injecting drug users in the 1970s and profiles of virus genotypes in the 1970s and 1990s.to examine the seroprevalence of hepatitis c virus (hcv) in the australian injecting drug-using community in the 1970s, and to compare the profile of hcv genotypes with that seen in the 1990s.200010914104
clearance of hepatitis c viremia associated with cellular immunity in the absence of seroconversion in the hepatitis c incidence and transmission in prisons study cohort.understanding the earliest virological and immunological events in acute hepatitis c virus (hcv) infection may provide insight into the determinants of protective immunity. four cases of hcv viremia with subsequent viral clearance, but without biochemical hepatitis or anti-hcv seroconversion, are reported from a prospective cohort study of prison inmates. two of the subjects who developed sustained viremia were assessed for production of interferon (ifn)- gamma, by use of the enzyme-linked immun ...200415122521
bug breakfast in the bulletin: blood-borne viruses in correctional facilities. 200516596152
harm reduction, hepatitis c and opioid pharmacotherapy: an opportunity for integrated hepatitis c virus-specific harm reduction.while harm reduction advocates, policy makers and practitioners have a right to be proud of the impact of interventions such as needle and syringe programmes on hiv risk, we can be less sanguine about the ongoing high levels of hcv transmission among injecting drug users (idus) and the expanding burden of hepatitis c virus (hcv)-related liver disease. in this harm reduction digest drs byrne and hallinan from the redfern clinic and dr dore from the national centre in hiv epidemiology and clinical ...200717564882
screening for hepatitis c in sexual health clinic attendees.hepatitis c virus (hcv) prevalence has been shown to be higher in some sexual health clinic attendees than the general population. screening for hcv in sexual health clinics may be based on risk assessment or universal screening. the aim of this audit was to explore the value of routine hcv screening in a sexual health centre population.200818361858
prevalence of and risk factors for hepatitis c in aboriginal and non-aboriginal adolescent offenders.to define and compare the prevalence, risk factors and understanding of hepatitis c transmission among aboriginal and non-aboriginal young offenders.200818484939
hepatitis c virus infection in south australian prisoners: seroprevalence, seroconversion, and risk factors.to determine entry antibody seroprevalence and seroconversion to hepatitis c virus (hcv) and associated risk factors in newly incarcerated prisoners.200918790659
vaccination and screening of medical students: results of a student health initiative.to evaluate the immune status and vaccination needs of first-year medical students in relation to bloodborne viruses and common vaccine-preventable diseases.200818976187
chronic hepatitis b and c infection in children in new south wales.to characterise epidemiological, clinical and laboratory features of children in new south wales with chronic hepatitis b (hbv) or c (hcv) infections.200919527200
the epidemiology of hepatitis c in australia: notifications, treatment uptake and liver transplantations, 1997-2006.regular monitoring of hepatitis c (hcv)-related surveillance data is essential to inform and evaluate strategies to reduce the expanding hcv burden. the aim of this study was to examine trends in the epidemiology and treatment of hcv in australia.200919798783
estimating population attributable risk for hepatitis c seroconversion in injecting drug users in australia: implications for prevention policy and planning.to determine risk factors and estimate their population-level contribution to hepatitis c virus (hcv) burden.200919804463
uptake and delivery of hepatitis c treatment in opiate substitution treatment: perceptions of clients and health professionals.uptake of treatment for hepatitis c virus (hcv) infection is very low particularly among people who have injected drugs. opiate substitution treatment (ost) programs, with a high prevalence of people living with hcv, have been a site of growing interest in the delivery of hepatitis c treatment. there has been no exploration of ost clients' and health professionals' perceptions of the barriers and facilitators to uptake and delivery of hcv treatment in ost clinics from personal and organizational ...201020070504
establishment of a successful assessment and treatment service for australian prison inmates with chronic hepatitis c.to evaluate the assessment and treatment outcomes of a prison hepatitis service.201020438418
early il-10 predominant responses are associated with progression to chronic hepatitis c virus infection in injecting drug users.the critical events in clearance or persistence of hepatitis c virus (hcv) infection are unknown but likely to be determined early in acute infection. type 1 and type 2 cytokine production was assessed by hcv peptide elispot and multiplex in vitro cytokine production assays in longitudinally collected samples from 20 untreated participants enrolled in the australian trial in acute hepatitis c (atahc); a prospective cohort of acute hcv infection (77% injecting drug users, idu). significantly high ...201020626625
incidence of primary hepatitis c infection and risk factors for transmission in an australian prisoner cohort.hepatitis c virus (hcv) infection is common in prisoner populations, particularly those with a history of injecting drug use (idu). previous studies of hcv incidence have been based on small case numbers and have not distinguished risk events in prison from those in the community.201020964864
frequent multiple hepatitis c virus infections among injection drug users in a prison setting.recent data indicate that multiple hepatitis c virus (hcv) infections (mixed infection, superinfection, and reinfection) are common among injection drug users (idus). in this study, we identified and characterized multiple hcv infection episodes among hcv-seronegative idu prison inmates (n = 488) enrolled in the hepatitis c incidence and transmission study cohort. incident hcv infection with detectable hcv rna was identified in 87 subjects, 48 of whom completed additional follow-up to screen for ...201021038409
factors associated with hepatitis c knowledge among a sample of treatment naive people who inject drugs.assessment and uptake of treatment for hepatitis c among people who inject drugs (pwid) is low and strategies to enhance hepatitis c care in this group are needed. knowledge of hepatitis c and its treatment is one precursor to decisions about treatment.201021194852
trends in all cause and viral liver disease-related hospitalizations in people with hepatitis b or c: a population-based linkage study.previous studies have reported an excess burden of cancer and mortality in populations with chronic hepatitis b (hbv) or c (hcv), but there are limited data comparing hospitalization rates. in this study, we compared hospitalization rates for all causes and viral liver disease in people notified with hbv or hcv in new south wales (nsw), australia.201121261993
incidence of hepatitis-c among hiv infected men who have sex with men (msm) attending a sexual health service: a cohort study.we aimed to determine the incidence of hepatitis c (hcv) infection among hiv-infected men who have sex with men (msm) attending a sexual health centre.201121291565
transmission of hepatitis c virus to recipients of parenteral vitamin therapy in a primary care facility.the australian prevalence of hepatitis c virus (hcv) is approximately 1%, with the majority of cases acquired through injecting drug use. however, occasionally hcv infection occurs in healthcare settings. three new hcv infections were identified amongst patients attending a general practice in sydney, australia, specialising in parenteral vitamin therapy.201121507711
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