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prevalence of anti-hcv antibody in blood donors in the tokyo area.prospective studies of posttransfusion hepatitis carried out in the past decade showed that 18.1% of the blood transfusions resulted in non-a non-b hepatitis in japan. as an approach to the prevention of posttransfusion non-a non-b hepatitis (ptnanb), anti-hepatitis c virus (hcv) positivity was measured in 2,970 blood donations in the tokyo area, and in 200 children aged between 6 and 15 years. thirty-four cases were anti-hcv-positive, showing an overall positivity of 1.14%. none of the 200 chil ...19902173281
prevalence of hcv genotype among patients with chronic liver diseases in the tokyo metropolitan area.we examined 613 toranomon hospital patients with hcv rna-positive chronic liver disease to elucidate the viral genotype in the tokyo metropolitan area. an epidemiological and clinical study was conducted in the 565 patients whose hcv genotype could be determined. the hcv genotypes found were type ii, in 414 patients (67.5%); type iii, in 103 (16.8%); type iv, in 37 (6.0%); type v, in 4 (0.7%); mixed genotype ii and iii, in 5 (0.8%); and mixed genotype ii and iv, in 2 (0.3%). the hcv genotype cou ...19948000505
hepatitis c virus subtype 3b infection in a hospital in japan: epidemiological study.to elucidate the epidemiology of infection with hepatitis c virus (hcv) subtype 3b (a rare subtype thought to have originated in southeast asia) in japan, we examined the genotypic subtype in 1397 patients with hcv-related chronic liver diseases. of 1330 patients with identified hcv rna genotypes. 960 had subtype 1b, 243 had subtype 2a, 97 had subtype 2b, 14 (1.1%) had subtype 3b, and 16 had other types of hcv or mixed subtypes. the age, gender, and severity of liver disease in patients with hcv ...19969027642
evaluation of third generation anti-hcv test kit (synpep hcv-eia ii) using sera of inhabitants from hcv hyperendemic area.we examined the characteristics and usefulness of a third generation anti-hcv test kit, synpep hcv-eia ii (kyokuto pharmaceutical inc., tokyo, japan). the sera of inhabitants from a hepatitis c virus (hcv) hyperendemic area were used. the kit had even or more anti-hcv detection sensitivity and reproducibility than ortho hcv iii elisa test system (ortho-clinical diagnostic k.k., tokyo, japan) or hcv pha 2nd generation (dinabot co., ltd., tokyo, japan). synpep hcv-eia ii needed less total reaction ...19989658756
poor association of tt virus viremia with hepatocellular carcinoma.the aim of this study was to clarify the relationship between tt virus (ttv) infection and the development of hepatocellular carcinoma.200010902976
prevalence of human immunodeficiency virus, hepatitis b and hepatitis c virus antibodies and hepatitis b antigen among commercial sex workers in japan.to investigate the prevalence of antibodies to human immunodeficiency virus (hiv), hepatitis b virus (hbv) and hepatitis c virus (hcv), and of hepatitis b surface (hbs) antigen in commercial sex workers (csw) who attended a sexually transmitted disease (std) clinic in tokyo.200111916178
twenty-four weeks of interferon alpha-2b in combination with ribavirin for japanese hepatitis c patients: sufficient treatment period for patients with genotype 2 but not for patients with genotype 1.hepatitis c virus (hcv) rna titer and hcv genotype are two major determinants of the outcome of interferon (ifn) monotherapy. to clarify the usefulness of combination therapy with ifn and ribavirin in japanese hepatitis c patients, we treated patients with a relatively high dose of ifn in combination with ribavirin for 24 weeks and examined the effects in relation to the viral parameters.200616761995
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