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[mutations within the interferon sensitivity determining region in korean patients infected with hepatitis c virus genotype 1b].the treatment response to interferon could differ with mutations in the interferon-sensitivity-determining region (isdr) in patients infected with hepatitis c virus (hcv) genotype-1b (hcv-ib). we examined the pattern of isdr mutations and analyzed whether the number of amino acid substitutions influences the treatment response to peginterferon plus ribavirin in chronic hepatitis or cirrhotic patients infected with hcv-ib.201020606500
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