| frequent detection of hepatitis c virus subtype 3a (hcv-3a) isolates in thailand by pcr using subtype-specific primers. | by means of a polymerase chain reaction (pcr) method using subtype-specific primers for hepatitis c virus (hcv) subtypes 1a, 1b, 2a, 2b and 3a, the prevalence of each subtype among hcv isolates in chiang mai, thailand, was determined. hcv-3a appeared to be the most common subtype in blood donors, and was also frequently found in patients with liver disease. hcv-1b, but not hcv-2a or -2b, was also commonly found in this area, while a considerable percentage of the total hcv isolates still remaine ... | 1995 | 7544428 |
| analysis of hepatitis c virus isolates among healthy blood donors and drug addicts in chiang mai, thailand. | hepatitis c virus (hcv) isolates obtained from 25 anti-hcv antibody-positive healthy blood donors and 29 drug addicts in chiang mai, thailand, were analyzed. hcv rna was detected in 23 blood donor samples (92%) and 24 drug addict blood samples (83%) by pcr for a portion of the ns5 region. subtype analysis revealed that hcv type 3a (hcv-3a) was the prevailing subtype (30%), which was followed in prevalence by hcv-1a (21%), -1b (13%), -3b (13%), and -6a (2%). six (13%) of the 47 isolates showed lo ... | 1994 | 7814558 |
| infectious disease markers in blood donors in northern thailand. | a major epidemic of human immunodeficiency virus type 1 (hiv-1) infections that are primarily due to heterosexual transmission has developed in thailand since 1988. the epidemic has been most severe in northern thailand. the blood banks in chiang mai began screening donors for hiv-1 antibodies in february 1988 and for p24 antigen in april 1992. | 1995 | 7878721 |
| differential distribution of hepatitis c virus subtypes in asia: comparative study among thailand, indonesia, the philippines and japan. | hepatitis c virus (hcv) is currently classified into at least six major genotypes, each of which is further divided into a number of subtypes. it has been reported that prevalence of each subtype varies among different geographical regions of the world and that severity of liver disease and sensitivity to interferon treatment varies with different subtypes. the purpose of this study was to determine and compare the prevalence of each subtype among hcv isolates in different areas in asia such as ... | 1997 | 9640596 |
| complete genomes for hepatitis c virus subtypes 6f, 6i, 6j and 6m: viral genetic diversity among thai blood donors and infected spouses. | in this study, the first complete genome sequences for hepatitis c virus (hcv) subtypes 6f, 6i, 6j and 6m, obtained from infected blood donors in chiang mai, thailand, are reported. pairwise genome-wide nucleotide similarities between some of these isolates were higher than the 75-80% value used previously to define different hcv subtypes. to investigate further, the entire genomes of four prototype isolates, th602 (6i), th553 (6j), b4/92 (6m) and d86/93 (6n), were sequenced. pairwise comparison ... | 2007 | 17412980 |
| evaluation of a multiplex human immunodeficiency virus-1, hepatitis c virus, and hepatitis b virus nucleic acid testing assay to detect viremic blood donors in northern thailand. | screening of blood donors with nucleic acid testing (nat) for human immunodeficiency virus (hiv) and hepatitis c virus (hcv) has been implemented recently in the united states. there are limited data, however, on the additional nat yield of donors in developing countries in asia where the prevalence of infection is higher. in addition, data on hepatitis b virus (hbv) nat in high prevalence areas are minimal. | 2007 | 17880604 |
| occult hepatitis c virus infection during an outbreak in a hemodialysis unit in thailand. | control of hepatitis c virus (hcv) in hemodialysis populations is a major public health priority, but the preferred methods to prevent and rapidly detect hcv outbreaks in these populations remains subject to debate. we enrolled 231 hemodialysis patients at three dialysis centers in chiang mai, thailand. patients were followed every 6 months for 3 years and tested for the presence of serum hcv antibody and hcv rna at each visit. we additionally isolated and tested peripheral blood mononuclear cel ... | 2008 | 18360894 |