| molecular epidemiology of hcv among health care workers of khyber pakhtunkhwa. | studies of the molecular epidemiology and risk factors for hepatitis c virus (hcv) in health care workers (hcws) of peshawar, khyber pakhtunkhwa region are scarce. lack of awareness about the transmission of hcv and regular blood screening is contributing a great deal towards the spread of hepatitis c. this study is an attempt to investigate the prevalence of hcv and its possible association with both occupational and non-occupational risk factors among the hcws of peshawar. | 2011 | 21385397 |
| prevalence of active hcv infection among the blood donors of khyber pakhtunkwa and fata region of pakistan and evaluation of the screening tests for anti-hcv. | hepatitis c is a fatal liver disease caused by the hepatitis c virus. in this study, blood donors, from various districts of the kpk province and the federally administered tribal area (fata) of pakistan were tested for anti-hcv antibodies and hcv rna by ict (immuno-chromatographic test), elisa and rt-pcr. out of the 7148 blood donors, 224 (3.13%) were positive for anti-hcv antibodies by ict, 135 (1.89%) by elisa while 118 (1.65%) blood donors had active hcv infection as detected by rt-pcr. we s ... | 2011 | 21457531 |
| frequency distribution of hcv genotypes among chronic hepatitis c patients of khyber pakhtunkhwa. | abstract: background: hepatitis c virus (hcv) genotypes frequency is important for the predication of response to therapy and duration of treatment. despite variable response rates experienced in the case of interferon (ifn) -based therapies, there was scarcity of data on hcv genotypes frequency in khyber pakhtunkhwa (kpk). study design a total of 200 blood samples were collected from chronic hcv patients prior to the initiation of anti-viral therapy. the study population included patients from ... | 2011 | 21521506 |
| prevalence of hcv among the high risk groups in khyber pakhtunkhwa. | hepatitis c is an infectious disease, caused by blood borne pathogen; the hepatitis c virus. in this study we analyzed blood samples collected from various risk groups for the prevalence of anti-hcv and active hcv infection with the help of immunochromtographic tests and nested pcr. the prevalence of active hcv infection among the high risk groups was 15.57% (26/167). the prevalence of hcv in individual risk groups was 15%, 28%, 8%, 14.28% and 14.28% in the case of thalassemics, dialysis, major ... | 2011 | 21663685 |
| active hepatitis c infection and hcv genotypes prevalent among the idus of khyber pakhtunkhwa. | abstract: injection drug users (idus) are considered as a high risk group to develop hepatitis c due to needle sharing. in this study we have examined 200 injection drug users from various regions of the khyber pakhtunkhwa province for the prevalence of active hcv infection and hcv genotypes by immunochromatographic assays, rt-pcr and type-specific pcr. our results indicated that 24% of the idus were actively infected with hcv while anti hcv was detected among 31.5% cases. prevalent hcv genotype ... | 2011 | 21711541 |
| hepatitis c virus genotypes in pakistan: a systemic review. | background and aim: phylogenetic analysis has led to the classification of hepatitis c virus (hcv) into 1-6 major genotypes. hcv genotypes have different biological properties, clinical outcome and response to antiviral treatment and provide important clues for studying the epidemiology, transmission and pathogenesis. this article deepens the current molecular information about the geographical distribution of hcv genotypes and subgenotypes in population of four provinces of pakistan. 34 publish ... | 2011 | 21902822 |
| hepatitis c virus genotypes circulating in district swat of khyber pakhtoonkhaw, pakistan. | hepatitis c virus (hcv) is the leading cause of chronic hepatitis worldwide and its subtypes/genotypes are clinically important for clinical management and vaccine development. the present study describes frequency distribution of different hcv genotypes and their treatment status in hcv rna positive patients from district swat. a total of 185 hcv infected sera were analyzed by molecular genotyping assay. the most prevalent genotype was 3a (34.1%), followed by 2a (8.1%), 3b (7%) and 1a (5.4%). t ... | 2011 | 21235746 |
| molecular epidemiology of hepatitis c virus genotypes in khyber pakhtoonkhaw of pakistan. | six major hepatitis c virus (hcv) genotypes and hundreds of subtypes have been identified globally. all these genotypes are generally studied for epidemiology, their vaccine development and clinical management. this article comments the frequency distribution of various hcv genotypes circulate in different areas/districts of khyber pakhtoonkhaw province of pakistan. sum of 415 hcv rna pcr positive sera samples were tested by a molecular genotyping assay. data analysis revealed that out of these ... | 2010 | 20796270 |