| the outcome of commercial kidney transplant tourism in pakistan. | the lack of cadaver organs for transplantation motivates some balkan patients to go to developing countries to buy a kidney. we have followed 36 patients who received kidney transplants in lahore and rawalpindi, pakistan. the patients had not been cleared for transplantation with a standard pre-transplant work-up: 80% were hepatitis-c virus (hcv) or hbsag positive. during follow-up, seven patients died. sixteen patients experienced wound infections with post-operative hernias, and three patients ... | 2011 | 20626425 |
| promiscuous prediction and conservancy analysis of ctl binding epitopes of hcv 3a viral proteome from punjab pakistan: an in silico approach. | hcv is a positive sense rna virus affecting approximately 180 million people world wide and about 10 million pakistani populations. hcv genotype 3a is the major cause of infection in pakistani population. one of the major problems of hcv infection especially in the developing countries that limits the limits the antiviral therapy is the long term treatment, high dosage and side effects. studies of antigenic epitopes of viral sequences of a specific origin can provide an effective way to overcome ... | 2011 | 21303499 |
| investigating the concurrent presence of hcv in serum, oral fluid and urine samples from chronic hcv patients in faisalabad, pakistan. | hepatitis c virus (hcv) is normally present in the blood of infected patients; however, it can also be present in some other body fluids. therefore, in this study, a concurrent presence of hcv-rna was investigated in oral fluid and urine of 80 pakistani chronic hcv patients. hcv-rna was detected in 31 (38.8%) oral fluid and 10 (12.5%) urine samples using rt-pcr in all 80 of the patients whose sera tested positive for hcv-rna. from this study, it is concluded that, in addition to the blood, hcv r ... | 2009 | 19669078 |
| high prevalence of hepatitis c virus infection in the largest province of pakistan. | to estimate the prevalence and spectrum of hepatitis c virus (hcv) infection in the general population of pakistan. | 2008 | 18419643 |
| an evidence of high prevalence of hepatitis c virus in faisalabad, pakistan. | to see the prevalence of hepatitis c virus (hcv) and its genotypes in general population of the locality and to evaluate the importance of reverse transcriptase-polymerase chain reaction (rt-pcr) test over hcv antibody test in early diagnosis of hcv infection. | 2007 | 17334466 |
| is there a correlation between degree of viremia and liver histology in chronic hepatitis c? | to determine the correlation between degree of histological liver damage and serum hcv rna level in patients of chronic hepatitis c, in order to evaluate the usefulness of hcv rna estimation as an alternate to liver biopsy. | 2004 | 15518372 |
| hepatitis c virus genotypes in pakistan: a systemic review. | background and aim: phylogenetic analysis has led to the classification of hepatitis c virus (hcv) into 1-6 major genotypes. hcv genotypes have different biological properties, clinical outcome and response to antiviral treatment and provide important clues for studying the epidemiology, transmission and pathogenesis. this article deepens the current molecular information about the geographical distribution of hcv genotypes and subgenotypes in population of four provinces of pakistan. 34 publish ... | 2011 | 21902822 |
| age-specific frequency of screen-detected hepatitis c virus seropositivity in men from the punjab province of pakistan. | pakistan is a south asian country with a high population seroprevalence of anti-hepatitis c virus (anti-hcv) antibody. in administrative districts of its most populous province, punjab, the frequency of seropositivity for hcv in different age groups of adult men, the usual bread winners for their families, is not known. this study describes the frequency and age-distribution of seropositivity for anti-hcv antibodies in 58,680 clinically healthy, adult men, from nine districts of the punjab provi ... | 2010 | 21258133 |
| occult hepatitis c virus infection and associated predictive factors: the pakistan experience. | the aim of the present study was to determine the presence of hcv rna in the liver biopsies of patients with abnormal liver tests but without detectable serum hcv rna and anti-hcv antibodies in sera. liver biopsies and whole blood of total 31 patients who were negative for anti-hcv antibodies with elevated liver function tests were received at division of molecular diagnostics, university of the punjab pakistan from january 2002 to june 2009 for the detection of hcv rna. hcv rna status of the su ... | 2010 | 21184846 |
| frequency distribution of hepatitis c virus genotypes in different geographical regions of pakistan and their possible routes of transmission. | information regarding hepatitis c virus genotypes and subtypes circulating in pakistan and various risk factors for their transmission are not known well. the specific objective of this study was to find out the frequency of various hcv genotypes present in well-characterized pakistani hcv isolates and their possible routes of transmission. | 2008 | 18498666 |