Publications

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gb virus c prevalence in blood donors and high risk groups for parenterally transmitted agents from gauteng, south africa.the prevalence of gbv-c infection in voluntary blood donors and in groups at high risk for parenteral exposure to infectious agents was studied. the high risk groups included chronic renal failure patients on haemodialysis, renal transplant patients and haemophiliacs from gauteng. the presence of gbv-c rna in these populations was determined using reverse transcription polymerase chain reaction (rt-pcr) in the 5' non-coding region (ncr) of the virus. of the blood donors, 11.1% (95% ci 7.6, 15.8) ...19989598929
bloodborne viruses in forensic medical practice in south africa.health care workers are at risk of exposure to bloodborne viruses including human immunodeficiency virus types 1 and 2 (hiv-1 and -2), hepatitis b virus (hbv) and hepatitis c virus (hcv). however, limited data is available regarding these risks to forensic medical personnel who are exposed daily to large numbers of severely traumatized bodies in south africa, a country that has an existing and growing hiv epidemic and a high hbv seroprevalence. because no specific prescriptions ensuring occupati ...199910624931
hepatitis b and c virus infections and liver function in aids patients at chris hani baragwanath hospital, johannesburg.impaired liver function tests and co-infection with hepatitis viruses in aids patients are common in western countries.200010944831
hepatitis c virus genotypes in two different patient cohorts in johannesburg, south africa.previous studies in south african patients have shown that hepatitis c virus (hcv) prevalence is low (2.6%) and genotype 5 is the dominant genotype. this is the first sequence-based genotype study from this country on two different patient groups (haemophiliacs (h) and liver disease (ld) patients) over two time periods (2000-2002 and 2007). genotype 5 was found to be the dominant genotype in the ld groups, but genotype 1 dominated in the h group. genotype 2, and a higher prevalence of genotype 3 ...200818946631
transfusion-transmissible virus and hepatocellular carcinoma: a case-control study.although transfusion-transmissible virus (ttv) is often present in the serum of patients with acute and chronic non-a-c liver diseases, its hepatotropism, pathogenicity to the liver and hepatocarcinogenicity have not been proven. we used a case-control format to compare the prevalence of ttv infection among 148 southern african blacks with hepatocellular carcinoma and 148 matched hospital-based controls, and to test for possible interactive effects between this virus and hepatitis b virus (hbv) ...200010849266
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