| viral infections in kidney donors and recipients: a prospective study. | | 1977 | 194367 |
| epidemiologic study of prostatic cancer: preliminary report. | in a preliminary report on a small fraction of the projected subject population, some evidence in support of both sexual activity and venereal transmission hypotheses is accumulating. prostatic cancer cases, in contrast to hospitalized and/or neighborhood controls, are beginning to show greater proportions of selected sexual activities compatible with venereal transmission of an infectious agent, such as number of sexual partners, use of prostitutes, prior venereal disease, and genital infection ... | 1977 | 194689 |
| epidemiology of guillain-barré syndrome. | the only measures of morbidity for guillain-barré syndrome in well-defined populations in the continental united states come from olmsted county, minnesota, and san joaquin county, california. the estimated incidence rates are between 1 and 2 cases per 100,000 population per year. despite the hazards of generalizing from such small samples, these are the only estimates available. large case series have suggested that the syndrome is more common in males, that it may occur at any age, and that it ... | 1978 | 369322 |
| mayo clinic experience with allogeneic and syngeneic bone marrow transplantation, 1982 through 1990. | between april 1982 and july 1990, 101 patients underwent allogeneic or syngeneic bone marrow transplantation at the mayo clinic. this patient population consisted of 30 with acute nonlymphocytic leukemia, 25 with acute lymphoblastic leukemia, 29 with chronic granulocytic leukemia, and 17 with other diseases (aplastic anemia in 7, myelodysplastic syndrome in 5, and lymphoma in 5). the results achieved in our patients who underwent transplantation in first complete remission of both acute nonlymph ... | 1992 | 1312187 |
| outcome of recipients of bone marrow transplants who require intensive-care unit support. | to determine the outcome and prognostic factors associated with bone marrow transplantation (bmt), we reviewed the clinical course of 35 adult recipients of such a transplant who were admitted to our intensive-care unit (icu). this constituted 24% of patients who underwent bmt for treatment of hematologic disorders during the study period. the reasons for admission to the icu were postsurgical care in 5, respiratory failure in 25, shock in 4, and renal failure in 1. the in-hospital mortality was ... | 1992 | 1545573 |
| treatment of end-stage chronic obstructive pulmonary disease with double lung transplantation. | six patients with end-stage emphysema (age 44 +/- 2 years) underwent double lung transplantation (tx) from june 1988 through may 1990. all suffered from severe inanition and required oxygen therapy. the ischemic time was 193 +/- 28 minutes. post-tx immune suppression was okt3 (14 days), cyclosporine (trough levels of 150 +/- 25 ng/ml), azathioprine to keep wbc at 3,000 to 5,000/cu mm (1 to 3.0 mg/kg/day) and following okt3, a tapering prednisone regimen. two rejection episodes that occurred in t ... | 1991 | 1847323 |
| the first 100 liver transplantations at the mayo clinic. | between march 1985 and june 1987, the first 100 liver transplantations at the mayo clinic were performed in 83 patients (primarily adults). the most frequent diagnoses were chronic active hepatitis (in 24 patients), primary sclerosing cholangitis (in 22), and primary biliary cirrhosis (in 20). the median operating time was 406 minutes, and the median usage of erythrocytes was 13.2 units. a venovenous bypass was used in all patients older than 10 years of age. hepatic artery thrombosis occurred i ... | 1989 | 2642999 |
| the role of parvovirus b19 in the pathogenesis of giant cell arteritis: a preliminary evaluation. | to determine whether parvovirus b19 dna is more likely to be present in the temporal arteries of patients with giant cell arteritis (gca) than in the temporal arteries of control subjects. | 1999 | 10366119 |
| randomized clinical trial of ganciclovir vs acyclovir for prevention of cytomegalovirus antigenemia after allogeneic transplantation. | cytomegalovirus (cmv) disease remains a major cause of morbidity following allogeneic stem cell transplantation (sct). in a prospective randomized trial, we tested prophylactic therapy with ganciclovir or acyclovir for patients at high risk of disease. ninety-one cmv seropositive recipients of related (n = 53) and unrelated (n = 38) donor transplants were enrolled. all patients received intravenous (i.v.) ganciclovir 5 mg/kg every 12 h days -7 to -2, followed by acyclovir 10 mg/kg i.v. every 8 h ... | 2002 | 12476289 |
| chronic rejection: the next major challenge for pancreas transplant recipients. | with newer immunosuppressive agents, acute rejection and graft loss resulting from acute rejection have become less common for pancreas transplant recipients. as long-term graft survival rates have improved, an increasing number of grafts are being lost to chronic rejection (cr). we studied the incidence of cr and identified risk factors. | 2003 | 14508354 |
| evolution of immunosuppression at the university of minnesota. | immunosuppressive protocols at the university of minnesota have evolved from identical immunosuppression for all recipients (prednisone, azathioprine, and antilymphocyte globulin) to differing protocols for living (triple therapy) and cadaver (sequential therapy) donor recipients, and then to our current protocol in which all recipients receive induction therapy with rapid discontinuation of prednisone. at the same time, progress has been made in the prevention and treatment of cytomegalovirus i ... | 2004 | 15041309 |
| effect of infectious diseases on outcome after heart transplant. | to determine how often cardiac allograft recipients develop infectious diseases and how the infections affect these patients. | 2008 | 18315996 |
| emergence of drug-resistant cytomegalovirus in the era of valganciclovir prophylaxis: therapeutic implications and outcomes. | valganciclovir prophylaxis is reportedly associated with a low incidence of ganciclovir-resistant cytomegalovirus (cmv). we assessed the incidence, clinical features, and outcome of drug-resistant cmv among solid organ transplant patients who received valganciclovir prophylaxis. | 2008 | 18339135 |
| incidence and clinical characteristics of ocular infections after heart transplantation: a retrospective cohort study. | ocular infections associated with organ transplantation are well documented following renal and liver transplantation; however, few studies have reported ocular infections following heart transplant. | 2009 | 19573087 |
| detection of cytomegalovirus dna in dried blood spots of minnesota infants who do not pass newborn hearing screening. | up to 15% of infants with asymptomatic congenital cytomegalovirus (cmv) infection will experience some degree of sensorineural hearing loss. many infants who fail newborn hearing screening (nhs) are likely to have congenital cmv infection, but may escape definitive virologic identification because diagnostic evaluation may not commence until several weeks or months of age, making differentiation between congenital and postnatal cmv infection difficult. early diagnosis linking virologic identific ... | 2009 | 19820425 |