| nosocomial pneumonia in patients having bone marrow transplant. attributable mortality and risk factors. | the authors performed a matched historic cohort study to determine the attributable mortality and risk factors for nosocomial pneumonia in bone marrow transplant (bmt) recipients. all patients with nosocomial pneumonia at a university tertiary care center were identified by a prospective surveillance system between 1980 and 1988. control patients were selected from the population of bmt patients. the crude mortality for 55 patients with nosocomial pneumonia was 74.5% (95% confidence interval [ci ... | 1992 | 1315207 |
| nosocomial pneumonia in adult patients undergoing bone marrow transplantation: a 9-year study. | two hundred seventy-five consecutive patients treated with bone marrow transplantation (bmt) during a 9-year interval were analyzed for the incidence and etiology of nosocomial pneumonia. cases included adults who acquired pneumonia during the first hospitalization period within 100 days of the transplant. fifty-five (20%) of the 275 patients developed nosocomial pneumonia, and the crude mortality during the hospitalization period was 74.5%. an etiology was established in 67.3% (37 of 55) of epi ... | 1991 | 1845875 |
| human cytomegalovirus a sequence and ul144 variability in strains from infected children. | human cytomegalovirus (hcmv) displays genetic polymorphisms. this variability may contribute to strain-specific tissue tropism and disease expression in hcmv-infected humans. to determine strain variability in a sequence and ul144 gene regions, 51 low-passage isolates from 44 hcmv-infected children were studied. isolates were obtained from 28 healthy children attending child care centers in iowa and from 16 congenitally infected infants born in texas. isolates demonstrated substantial nucleotide ... | 2001 | 11505449 |
| cytomegalovirus transmission in child care homes. | children attending child care centers have high rates of cytomegalovirus (cmv) excretion. women exposed to such children have an increased risk of acquiring cmv infection, and primary infection places the offspring of such women at risk of congenital cmv infection. we studied family child care homes to determine if this child care alternative might represent a safe haven from cmv. | 1999 | 9895003 |
| epidemiology of congenital cytomegalovirus infection: maternal risk factors and molecular analysis of cytomegalovirus strains. | to determine factors that influence the occurrence of congenital cytomegalovirus (cmv) infection, the authors surveyed prospectively 8,254 infants born in eastern iowa between october 1989 and june 1994. the authors conducted a case-control study to identify maternal risk factors, matching each cmv-infected infant with three uninfected infants according to hospital and date of birth. cmv strains were compared by using the polymerase chain reaction (pcr) to identify common sources of infection. o ... | 1998 | 9596472 |
| cytomegalovirus reinfection in young children. | to determine the frequency of reinfection with new cytomegalovirus (cmv) strains in children in group child-care environments. | 1996 | 8774502 |
| simultaneous pancreas-kidney versus kidney-alone transplants in diabetics: increased risk of early cardiac death and acute rejection following pancreas transplants. | the decision between a simultaneous pancreas-kidney (spk) or kidney-alone (ka) transplant for the treatment of diabetic end-stage renal disease depends on the risk-versus-benefit of each procedure. in this study we compared the mortality, morbidity, graft function and acute rejection after 88 spk and 65 ka transplants. all acute rejection episodes were biopsy-proven. patient survival was higher in the ka group (ka 92%, spk 83%) at 1 year, but similar in both groups at 5 years (spk 78%, ka 71%). ... | 1994 | 8061363 |
| cytomegalovirus transmission in a midwest day care center: possible relationship to child care practices. | the epidemiology of cytomegalovirus (cmv) infection and transmission in a large iowa day care center was studied. over the 9 months of the study the overall cmv prevalence rates were 21% to 22%, with rates as high as 71% in toddlers. titers of cmv in the urine or saliva of infected children were as high as 3 x 10(4) plaque-forming units of cmv per milliliter, similar to titers of cmv observed in some congenitally infected infants. restriction enzyme analysis of cmv isolates from children in the ... | 1986 | 3014103 |
| the natural history of acquired cytomegalovirus infection among children in group day care. | we studied the natural history of cytomegalovirus (cmv) excretion among 79 children in a single day-care center over a 2 1/2-year period. during the study interval, 28 children (35%) excreted cmv in their urine, or saliva, or both. the cmv acquisition rate among children who were initially culture negative was 12.6% per year. in such children, cmv excretion began 11 to 59 months after entry into day care. the duration of cmv excretion varied from 3.0 to 28.4 months, with a mean of 13.0 +/- 9.1 m ... | 1988 | 2839977 |
| the epidemiology of cytomegalovirus infection among patients with burns. | to determine the epidemiology of cytomegalovirus (cmv) infections among patients with burns, we prospectively studied 120 burn patients admitted to the university of iowa burn center over a two-and-one-half year period. at the time of their admission, 44% of the patients had serologic evidence of prior cmv infection. among 44 seropositive patients, 23 (52%) had four-fold or greater rises in cmv antibody titers. these patients had more severe burns (mean body surface area burn [bsab] 26.8%) than ... | 1990 | 2153725 |
| the occupational risk of cytomegalovirus infection among day-care providers. | we prospectively studied day-care providers at six day-care centers in south-eastern iowa to determine their occupational risk for primary cytomegalovirus infection and to define epidemiologic risk factors. ninety-six (38%) of 252 day-care providers were seropositive for cytomegalovirus by latex agglutination at entry into the study. among 82 seronegative providers available for follow-up, seven seroconversions occurred at only two of the six participating centers, yielding an annualized serocon ... | 1991 | 1846215 |