| studies of an outbreak of acute hepatitis a: ii. antibody changes to cytomegalovirus and herpersvirus. | the acute and convalescent sera from 14 schoolchildren with acute hepatitis a were tested for antibody changes to 70 viral antigens. marked decreases were noted in the levels of antibody to cytomegalovirus in 5 of the 14 children and in the levels of antibody to herpesvirus type 1 in 3. no such changes were noted in 9 sex- and age-matched healthy control children from the same classes. | 1977 | 204739 |
| comparative prevalence of subclinical cytomegalovirus and herpes simplex virus infections in the genital and urinary tracts of low-income, urban women. | the prevalence of subclinical infections caused by cytomegaloviruses (cmv) and herpes simplex viruses (hsv) was assessed simultaneously in the genital and urinary tracts of 1,101 indigent women. shedding of cmv from the genital and urinary tracts exceeded that of hsv by ninefold (8.89% vs. 0.95) and sevenfold (3.8% vs. 0.51%), respectively. pregnancy, regardless of gestational age, had no discernible influence on productive infection with either virus in either the genital or the urinary tract. ... | 1979 | 227972 |
| natural history of perinatal cytomegaloviral infection. | epidemiological data presented here indicate that cytomegaloviral (cmv) infection is one of the most common perinatal infections found in human beings. transmission to the offspring occurs in utero at birth and postnatally. intrauterine infection results from primary or recurrent maternal involvement, the latter being more common in populations where infection is initially acquired during childhood or adolescence, such as in low socioeconomic settings. congenital infection is usually subclinical ... | 1979 | 233356 |
| cytomegalovirus infection in sexually active adolescents. | to determine whether cytomegalovirus (cmv) infection in teenage girls is related to sexual activity, 254 girls 12-18 years old (mean, 15.8) attending a contraceptive counseling clinic were studied. participants were screened for chlamydia trachomatis, neisseria gonorrhoeae, and trichomonas vaginalis, and serum antibody to cmv was determined. demographic and sexual history data were collected by interview. the mean number of lifetime sex partners was 2.2; 173 (68%) were seropositive. race, greate ... | 1991 | 1847399 |
| increased rate of cytomegalovirus infection among day care center workers. | child care workers are potentially at risk for occupational exposure to cytomegalovirus, the leading cause of congenital infection in the united states. preschool children often shed cytomegalovirus and commonly transmit virus to peers and parents. workers from 32 day care centers were enrolled and tested for serum antibody to cytomegalovirus; 318 (62.5%) were seropositive. by logistic regression analysis the only variables significantly (p less than 0.05) associated with seropositivity at enrol ... | 1990 | 1973533 |
| cytomegalovirus infection among employees of a children's hospital. no evidence for increased risk associated with patient care. | employees of a children's hospital were studied to determine the prevalence of antibody to cytomegalovirus (cmv) and the incidence of cmv infection between 1984 and 1988 in relation to patient contact. at enrollment, 783 (63%) of 1250 employees had antibody to cmv. by logistic regression analysis, age greater than 30 years, black race, fewer than 16 years of education, employment for more than 1 year, female sex, and being married were each associated with seropositivity at enrollment. three hun ... | 1990 | 2153259 |
| leads from the mmwr. prevalence of cytomegalovirus excretion from children in five day-care centers. | | 1985 | 2982046 |
| increased rate of cytomegalovirus infection among parents of children attending day-care centers. | we screened parents of children from three previously studied day-care centers where children have maintained high rates of cytomegalovirus (cmv) excretion, as well as parents of children not in day-care centers (controls), for antibody to cmv. longitudinal serologic follow-up of seronegative parents revealed that 14 of 67 with children in the day-care centers acquired cmv, as compared with none of 31 controls (p less than 0.003). all 14 parents who seroconverted had a child who was shedding cmv ... | 1986 | 3010113 |
| prenatal screening of pregnant women for infections caused by cytomegalovirus, epstein-barr virus, herpesvirus, rubella, and toxoplasma gondii. | a service-oriented screening program for serologic detection of viral and parasitic infections during gestation is described for three different population groups. significance of a determination of primary cytomegalovirus infection is documented. a screening program for detection of immunity to rubella is recommended, but the feasibility of similar programs for herpes simplex virus and epstein-barr virus warrants further study. because of the low frequency of toxoplasmosis, education of patient ... | 1983 | 6297301 |
| increased frequency of cytomegalovirus infection in children in group day care. | the prevalence of cytomegalovirus (cmv) infection in 103 children attending a single day care center was compared with that of 62 children kept at home. demographic features of the day care group were similar to those of the home care group; in both groups, most of the children were white, were from middle-income families with two or fewer children, and had parents with 15 or more years of education. ten of 57 (18%) children in home care had serum antibody to cytomegalovirus (cmv) and 2/25 (8%) ... | 1984 | 6330661 |
| as us reviewer resigns over slur. | | 1995 | 7791861 |
| congenital cytomegalovirus disease in the louisville area: a significant public health problem. | using a passive surveillance system, 15 cases of symptomatic congenital cytomegalovirus (cmv) infection were identified in the louisville area over approximately 3 years. when compared to mothers delivering healthy infants in jefferson county, mothers of infants with congenital cmv were younger, more often nonwhite, and from lower socioeconomic status. affected infants had a lower mean gestational age and birth weight, and most demonstrated classic features of congenital cmv infection such as ja ... | 1994 | 7996040 |
| ocular abnormalities in congenital cytomegalovirus infection. | congenital cytomegalovirus (cmv) infection often results in damage to the brain, auditory system and visual system that leads to debility. this report describes the frequency, severity and effect on vision function of ocular abnormalities in a large cohort of children with congenital cmv infection. | 1996 | 8888845 |
| comparison of the efficacy and cost-effectiveness of pre-emptive therapy as directed by cmv antigenemia and prophylaxis with ganciclovir in lung transplant recipients. | | 2000 | 10967278 |
| congenital cytomegalovirus (cmv) infections: hats off to alabama. | | 2003 | 12915814 |
| risk factors for congenital cytomegalovirus infection in the offspring of young women: exposure to young children and recent onset of sexual activity. | two recognized sources of maternal cytomegalovirus infection are young children and sexual activity. previous studies evaluated either maternal exposures to young children or sexual activity, but these studies did not evaluate whether both of these maternal cytomegalovirus sources contribute to increases in congenital cytomegalovirus infections within populations with a high prevalence of infection among women of childbearing age. our objective with this study was to investigate whether maternal ... | 2006 | 16847076 |
| detection of cytomegalovirus infection during clinical trials of glycoprotein b vaccine. | preabsorption of sera with cytomegalovirus (cmv) glycoprotein b (gb) prior to testing for cmv igg antibody was evaluated for detection of cmv infection during cmv gb vaccine clinical trials. although, 98.2% of 109 cmv gb vaccine recipients were seropositive with a standard assay, preabsorption of sera with gb reduced their cmv antibody to extremely low levels compared with subjects with cmv infection. one subject who acquired cmv during a vaccine trial was easily identified by gb-absorbed cmv ig ... | 2004 | 15530699 |
| newborn hearing screening: will children with hearing loss caused by congenital cytomegalovirus infection be missed? | to predict whether universal newborn auditory screening will identify most infants with sensorineural hearing loss (snhl) caused by congenital cytomegalovirus (cmv) infection. | 1999 | 10393605 |
| symptomatic congenital cytomegalovirus infection in infants born to mothers with preexisting immunity to cytomegalovirus. | to determine the frequency of symptomatic congenital cytomegalovirus (cmv) infection in the offspring of women with a recurrent maternal cmv infection and to characterize the demographic and newborn findings. | 1999 | 10390260 |
| $1.6 million fraud award overturned. | | 1997 | 9019815 |
| the false claims act. litigating scientific misconduct. | | 1995 | 8570835 |
| maternal age and congenital cytomegalovirus infection: screening of two diverse newborn populations, 1980-1990. | cytomegalovirus (cmv) is the leading cause of congenital viral infection in the united states. to prevent damaging congenital cmv infections, it is necessary to have accurate population estimates of prevalence and to identify maternal factors associated with an elevated risk of congenital infection in the newborn. from 1980 through 1990, 17,163 offspring of predominantly low-income nonwhite women who delivered at a public hospital and 9892 newborns of predominantly mid- to upper-income white wom ... | 1993 | 8394857 |
| factors associated with primary cytomegalovirus infection during pregnancy. | we compared a group of 40 susceptible pregnant women who acquired cmv during gestation with a group of 86 women of similar race and socioeconomic background who remained seronegative to define factors associated with the risk of cmv infection during pregnancy. a logistic regression model using a stepwise procedure showed that a positive statistically significant correlation occurred with the age of the mother, the father's high-intensity contact with young children, and children living at home. ... | 1984 | 6330288 |
| prevalence and importance of congenital cytomegalovirus infection in three different populations. | a chilean population was compared to low-income and middle/upper-class populations in birmingham, ala., with regard to prevalence of congenital cytomegalovirus infection as well as the importance of this infection in neonatal deaths. in the highly seroimmune chilean (98%) and low-income birmingham (82%) groups, congenital infections occurred more often (1.7% and 1.9%, respectively) than in the less immune (56%) middle/upper-income group in birmingham (0.6%). in 407 autopsies reviewed in chile no ... | 1982 | 6292387 |
| cytomegalovirus infection in day-care center. | | 1982 | 6285192 |
| prevalence of cytomegalovirus excretion from children in five day-care centers--alabama. | | 1985 | 2984531 |