| natural history of opportunistic disease in an hiv-infected urban clinical cohort. | to determine the effect of contemporary clinical care on the natural history of opportunistic disease in an urban population infected with human immunodeficiency virus (hiv). | 1996 | 8607591 |
| costs to medicaid of advancing immunosuppression in an urban hiv-infected patient population in maryland. | human immunodeficiency virus (hiv) infection is increasingly an urban disease in the united states, and medicaid is the principal payer of the health care costs of patients with hiv. we wished to determine the costs to medicaid of patients in maryland infected with hiv as immunosuppression progresses, and to determine how costs varied by demographic characteristics of the patient. we analyzed combined economic and clinical data in patients from the johns hopkins hiv service, the provider of prim ... | 1997 | 9117454 |
| cytomegalovirus infection and the risk of mortality and frailty in older women: a prospective observational cohort study. | cytomegalovirus (cmv), a prevalent pathogen, causes severe disease in immunocompromised humans. however, present understanding is limited regarding the long-term clinical effect of persistent cmv infection in immunocompetent adults. the authors conducted a prospective observational cohort study (1992-2002) of 635 community-dwelling women in baltimore, maryland, aged 70-79 years in the women's health and aging studies to examine the effect of cmv infection on the risk of frailty, a common geriatr ... | 2010 | 20400465 |
| incidence of cytomegalovirus (cmv) retinitis in second eyes of patients with the acquired immune deficiency syndrome and unilateral cmv retinitis. | to evaluate the risk and risk factors for developing cytomegalovirus (cmv) retinitis in previously uninvolved second eyes among patients with unilateral cmv retinitis. | 2005 | 15953432 |
| t cell subsets and mortality in older community-dwelling women. | the relationship between specific t cell subset alterations and mortality has not been well characterized in older adults. the specific aim was to determine whether specific t cell subsets are associated with an increased risk of death. we conducted a case-control study of t cell subsets (cd4+ and cd8+ t cells, and subsets of these cells defined by expression or non-expression of cd28, cd45ra, and cd45ro) nested within two complementary prospective cohorts of women aged 65 and over living in the ... | 2005 | 15664735 |
| renal transplantation at the johns hopkins comprehensive transplant center. | a stagnant supply of transplantable organs in the face of a relentless burgeoning of transplant waiting lists has created a crisis. necessity continues to be the mother of invention and as the crisis has deepened it has served as a crucible for the development of new ways to think about perennial problems. our program has taken a 2-pronged approach to increasing the organ supply for our patients. first, through innovations like the laparoscopic donor nephrectomy, abo-incompatible and positive-cr ... | 2003 | 15387112 |
| risk of vision loss in patients with cytomegalovirus retinitis and the acquired immunodeficiency syndrome. | to characterize the effect of cytomegalovirus (cmv) retinitis and its treatment on visual acuity in patients with the acquired immunodeficiency syndrome. | 2003 | 12695243 |
| survival differences associated with treatment of cytomegalovirus retinitis in maryland patients with aids, 1987-1994. | differences in survival related to treatment of cytomegalovirus (cmv) retinitis in aids patients were studied. the medical records of adult aids patients who had been diagnosed with cmv retinitis in a maryland inpatient facility between september 1987 and september 1994 were reviewed to assess determinants of survival, including treatment with ganciclovir and foscarnet, use of zidovudine, and demographic characteristics. the review was based on inpatient and outpatient medical records and comput ... | 1999 | 10683128 |
| race and the treatment of cytomegalovirus retinitis in a cohort of patients with acquired immunodeficiency syndrome. | this historical cohort study assessed the impact of race on critical factors in the diagnosis and drug treatment of cytomegalovirus (cmv) retinitis in acquired immunodeficiency syndrome (aids) patients over a 7-year period. the study subjects included 194 adult patients with a history of aids who were treated for cmv retinitis between september 1987 and september 1994. abstracted inpatient hospital medical records and a statewide automated aids database were the primary sources of data. patients ... | 1998 | 9581441 |
| an epidemiologic and serologic comparison of uterine carcinoma in situ and squamous dysplasia. | | 1974 | 4368399 |
| interstitial pneumonitis after allogeneic bone marrow transplantation. nine-year experience at a single institution. | of 386 patients with allogeneic bone marrow transplants (bmt) treated during a 9-year interval, 166 developed interstitial pneumonitis (ip). idiopathic and cytomegalovirus (cmv) ip constituted 90% of the 113 cases in which tissue was examined. risk factors for ip overall were acute graft-versus-host disease (agvhd), remote transplant date, the diagnosis of leukemia, and gvhd prophylaxis with agents other than cyclosporine. risk factors for cmv ip were pre-transplant cmv seropositivity, cmv excre ... | 1988 | 2835573 |
| cytomegalovirus infection after autologous bone marrow transplantation with comparison to infection after allogeneic bone marrow transplantation. | cytomegalovirus (cmv) infection was detected in 65 of 143 (45%) autologous bone marrow transplant (bmt) patients. cmv pneumonitis occurred in only 2% of the patients and cmv retinitis occurred in none. infection occurred in half of the 40 initially seronegative patients and 47% of the 94 initially seropositive patients. among initially seropositive patients, platelet recovery was slower in infected patients than in those not infected (97 v 35 days median, p = .003), and neutrophil recovery was s ... | 1988 | 2833959 |
| delayed hypersensitivity skin testing and anergy in a population of gay men. | anergy is almost universal among patients with the acquired immunodeficiency syndrome (aids). to determine the prevalence and correlates of anergy in a population at risk for aids, we performed skin tests in 1120 gay men who were enrolled in a prospective study of the natural history of human immunodeficiency virus (hiv) infection. anergy, defined as no induration to any of four intradermal antigens, was present in 12%. individually, no induration was detected in response to tetanus toxoid (41%) ... | 1987 | 2822314 |