| rapid diagnosis of ebola hemorrhagic fever by reverse transcription-pcr in an outbreak setting and assessment of patient viral load as a predictor of outcome. | the largest outbreak on record of ebola hemorrhagic fever (ehf) occurred in uganda from august 2000 to january 2001. the outbreak was centered in the gulu district of northern uganda, with secondary transmission to other districts. after the initial diagnosis of sudan ebolavirus by the national institute for virology in johannesburg, south africa, a temporary diagnostic laboratory was established within the gulu district at st. mary's lacor hospital. the laboratory used antigen capture and rever ... | 2004 | 15047846 |
| serologic cross-reactivity of human igm and igg antibodies to five species of ebola virus. | five species of ebola virus (ebov) have been identified, with nucleotide differences of 30-45% between species. four of these species have been shown to cause ebola hemorrhagic fever (ehf) in humans and a fifth species (reston ebolavirus) is capable of causing a similar disease in non-human primates. while examining potential serologic cross-reactivity between ebov species is important for diagnostic assays as well as putative vaccines, the nature of cross-reactive antibodies following ebov infe ... | 2011 | 21666792 |
| ebola haemorrhagic fever among hospitalised children and adolescents in northern uganda: epidemiologic and clinical observations. | a unique feature of previous ebola outbreaks has been the relative sparing of children. for the first time, an out break of an unusual illness-ebola haemorrhagic fever occurred in northern uganda gulu district. | 2001 | 12789118 |
| complete genome sequence of an ebola virus (sudan species) responsible for a 2000 outbreak of human disease in uganda. | the entire genomic rna of the gulu (uganda 2000) strain of ebola virus was sequenced and compared to the genomes of other filoviruses. this data represents the first comprehensive genetic analysis for a representative isolate of the sudan species of ebola virus. the genome organization of the sudan species is nearly identical to that of the zaire species, but the presence of a gene overlap (between gp and vp30 genes) and a longer trailer sequence distinguish it from that of the reston species. a ... | 2005 | 16139097 |