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characterization of clinical isolates of mycobacterium paratuberculosis by dna-dna hybridization and cellular fatty acid analysis.the dna-dna homologies obtained were more than 90 per cent for all strains examined, including the reference strains of mycobacterium paratuberculosis and mycobacterium avium. consequently, in a genetic sense, m. paratuberculosis with its variants belong to a single species which should be considered a subspecies of m. avium. the same reference strains of m. paratuberculosis and m. avium showed small but distinct differences in the cellular fatty acid patterns. the norwegian goat isolate proved ...19883395476
identification of two groups of mycobacterium paratuberculosis strains by restriction endonuclease analysis and dna hybridization.genomic dna was prepared from four reference strains of mycobacterium paratuberculosis and 46 isolates of this organism from new zealand, australia, canada, and norway and also from two mycobactin-dependent "wood pigeon" strains. the dna was characterized by restriction endonuclease analysis, both with and without dna hybridization, with a probe specific to a repetitive dna sequence in m. paratuberculosis. both techniques differentiated m. paratuberculosis strains into two groups, but dna hybrid ...19902166089
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