Publications

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[an etiology study on the 1986 epidemic of acute hemorrhagic conjunctivitis in china].an epidemic of acute hemorrhagic conjunctivitis (ahc) broke out in shanghai, henan and fujian provinces of china in 1986. twenty four strains of etiologically suspected virus were then isolated but not correctly identified. in 1990 9 out of 24 strains from these three places were re-examined by us in our laboratory, and found feasible to be neutralized by ca 24v antiserum, but not by antiserum to ev 70 as once reported by henan. it was also found that these viruses (one strain from each of these ...19921327682
[etiology of 1988 epidemic of acute hemorrhagic conjunctivitis in beijing].an epidemic of acute hemorrhagic conjunctivitis (ahc) occurred in beijing during august-september in 1988. conjunctival swabs were collected from 50 ahc patients at the eye clinic of the peking union medical college hospital. 25 strains of viruses were isolated with hela cell cultures. all the viral isolates were identified as coxsackievirus a 24 variant (ca 24 v) with antiserum from the center for disease control, u. s. a. paired serum samples from 30 ahc patients were examined for neutralizing ...19902174765
[an etiological study of acute hemorrhagic conjunctivitis in beijing area in 1984].acute hemorrhagic conjunctivitis (ahc) has been widespread in china since 1971. an etiological survey of the sporadic outbreak in beijing was done in 1984. conjunctival swabs and sera were collected at the eye clinic of peking union medical college hospital and 10 strains of virus were isolated from 46 cases by culture on the hela cell line. 8 strains were identified as enterovirus 70 by homologous antiserum j 670/71 obtained from the california state laboratory of viral and rickettsial diseases ...19892547550
viral etiology of acute childhood encephalitis in beijing diagnosed by analysis of single samples.to understand the viral etiology of acute childhood encephalitis in beijing.19968933552
studies on the etiology of aseptic meningitis in peking. 196514333145
[sars-associated coronavirus gene fragments were detected from a suspected pediatric sars patient].a special "fever and cough" clinic was set up at the children's hospital affiliated to capital institute of pediatrics for children with symptoms of fever and cough in late april when the severe acute respiratory syndrome (sars) epidemic was at its peak in beijing to separate the children with fever from others during their visit to the outpatient department.200314733796
detection of viral agents in fecal specimens of monkeys with diarrhea.diarrheal disease is a major cause of morbidity and mortality in humans and animals, including non human primates. while the diagnostics for gastrointestinal bacterial and parasitic pathogens and their etiological role in disease are well established, little is known about the epidemiology, prevalence and role of viral agents in diarrheal illness among monkeys.200717493140
[study on the association of hand, foot and mouth disease and enterovirus 71/ca16 among children in beijing, 2007].to reveal the etiological agent of hand, foot and mouth disease in children in beijing.200718399150
multiple outbreaks of acute hemorrhagic conjunctivitis due to a variant of coxsackievirus a24: guangdong, china, 2007.acute hemorrhagic conjunctivitis (ahc) is usually caused by enterovirus 70, coxsackievirus a24(ca24v) and adenoviruses. several outbreaks of ahc caused by a ca24v have occurred since it was imported into china in 1971. multiple outbreaks of ahc reappeared in 10 cities of guangdong during june to november in 2007. the epidemic began in the june, and spread extensively, with a peak in the september. a total of 31,659 cases were reported to center for disease control and prevention of guangdong, it ...200818712817
[a case with hand, foot and mouth disease associated with central nervous symptoms related to enterovirus 71 in beijing]. 200819099718
[primary detection of pathogen from children with hand, foot, and mouth disease in beijing, 2007].we investigated the causative agents of hand, foot and mouth disease (hfmd) in children in beijing epidemic from april to june of 2007. totally, 82 specimens (including throat swabs, rectal swabs and vesicular swabs) were collected from 51 patients with hfmd. all patients had typical skin lesions, but no neurological manifestations. these clinical specimens were directly tested by rt-pcr assay with three primer sets: universal enterovirus, ca16-specific and ev71-specific primers. enterovirus, ca ...200919437882
prevalence of human respiratory viruses in adults with acute respiratory tract infections in beijing, 2005-2007.to determine the aetiological role and epidemiological profile of common respiratory viruses in adults with acute respiratory tract infections (artis), a 2-year study was conducted in beijing, china, from may 2005 to july 2007. nose and throat swab samples from 5808 arti patients were analysed by pcr methods for common respiratory viruses, including influenza viruses (ifvs) a, b, and c, parainfluenza viruses (pivs) 1-4, enteroviruses (evs), human rhinoviruses (hrvs), respiratory syncytial virus ...200919456830
[genetic characteristics of enterovirus 71 isolated in beijing, 2006-2008].objective to sequence and analyze the vp1 region of isolated enterovirus from different sources in beijing, 2006-2008.200919565848
[outbreak of acute hemorrhagic conjunctivitis in beijing city in 2007 caused by coxsackievirus a24 variant: molecular identification and phylogenetic analysis].in 2007, an outbreak of acute hemorrhagic conjunctivitis (ahc) occurred in beijing. in order to identify the etiology of this outbreak, 57 eye conjunctival swabs were collected from 57 outpatient patients, and detected for adenovirus, human enterovirus 70 (hev70) and coxsackievirus a24 variant (cva24v) genes by using rt-pcr or pcr methods. the results showed that 38 were positive for cva24v, the positive rate was 66.7%, but none was positive for hev70 and adenovirus, showing that this outbreak w ...200919769156
[genetic characterization of enterovirus 71 complete genome isolated in beijing, 2008].to investigate the characterization of the complete genome of ev71 in beijing, 2008 and to provide basis for selecting appropriate virus strain to develop vaccine.200919957602
[human enterovirus 71 was isolated from specimens of hand foot mouth disease in beijing in 2007].analyzing and identifying the type of enterovirus of human hand foot mouth disease (hfmd) outbreak in daxing district in beijing at the end of may in 2007.200920077674
[etiological analysis of enteric infectious diseases during beijing olympic games].to understand pathogen patterns of enteric infectious diseases and its impact on this pattern due to aggregation of a great deal of foreign visitors during beijing olympic games.200920137562
[study on the etiology of hand-foot-mouth disease outbreaks in beijing in 2007].to identify the etiology of 8 human hand-foot-mouth disease (hfmd) outbreaks in beijing, during may to july 2007.200920193198
[genetic analysis of vp1 sequences of enterovirus 71 isolated from patients of hand, foot and mouth disease in beijing, 2008].to get genetic information of vp1 coding region of hev71 in beijing in 2008.200920518331
prevalence of human coronaviruses in adults with acute respiratory tract infections in beijing, china.human coronaviruses (hcovs) are a common etiological agent of acute respiratory tract infections. hcov infections, especially those caused by the two hcovs identified most recently, nl63 and hku-1, have not been characterized fully. to evaluate the prevalence and clinical presentations of hku1 and nl63 in adults with acute respiratory tract infections, an investigation of hcov infections in beijing, china from 2005 to 2009 was performed by using reverse transcriptase pcr assays and sequencing an ...201121181925
[etiology of hand-foot-and-mouth disease and genetic characteristics of coxsackievirus a16 in beijing, 2009].this study aimed to reveal the pathogen spectrum of hand-foot-and-mouth disease (hfmd) and genetic characteristics of coxsackievirus a16 (coxa16) isolates in beijing in 2009. from 1044 clinical specimens collected from 975 hfmd cases at beijing pediatrics hospital, beijing you'an hospital and beijing ditan hospital in 2009, viral nucleic acids of enterovirus were detected by reverse transcriptase polymerase chain reaction (rt-pcr). enterovirus isolations were conducted with rhabdomyosarcoma (rd) ...201021344745
[rt-pcr identification and genetic characterizations of vp1 region of human enterovirus 71 isolated in beijing in 2008].to study the genetic characterizations of vp1 region of human enterovirus 71 (hev71) isolated from clinical specimens of hand, foot and mouth disease (hfmd) patients in beijing in 2008.201021604564
comparing enterovirus 71 with coxsackievirus a16 by analyzing nucleotide sequences and antigenicity of recombinant proteins of vp1s and vp4s.enterovirus 71 (ev71) and coxsackievirus a16 (ca16) are two major etiological agents of hand, foot and mouth disease (hfmd). ev71 is associated with severe cases but not ca16. the mechanisms contributed to the different pathogenesis of these two viruses are unknown. vp1 and vp4 are two major structural proteins of these viruses, and should be paid close attention to.201122050722
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