sesquiterpene lactones from the endemic cape verdean artemisia gorgonum. | leaves and flowers of artemisia gorgonum (asteraceae) collected in fogo, cape verde islands, were phytochemically investigated and resulted in isolation and characterization of three guaianolides 1, 2, 5, and a secoguainolide 4, in addition to eight known guaianolides 6-11 and two known germacranolides 12, 13. structures were elucidated by 1d and 2d nmr experiments. careful examination of the (13)c nmr spectrum led to revision of the structure of a previously described guaianolide from 2 to 3. m ... | 2008 | 19007951 |
analysis of malaria associated genetic traits in cabo verde, a melting pot of european and sub saharan settlers. | malaria has occurred in the cabo verde archipelago with epidemic characteristics since its colonization. nowadays, it occurs in santiago island alone and though prophylaxis is not recommended by the world health organization, studies have highlight the prospect of malaria becoming a serious public health problem as a result of the presence of antimalarial drug resistance associated with mutations in the parasite populations and underscore the need for tighter surveillance. despite the presumptiv ... | 2010 | 19837619 |