Publications

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epidemiological, clinical and biological features of malaria among children in niamey, niger.malaria takes a heavy toll in niger, one of the world's poorest countries. previous evaluations conducted in the context of the strategy for the integrated management of childhood illness, showed that 84% of severe malaria cases and 64 % of ordinary cases are not correctly managed. the aim of this survey was to describe epidemiological, clinical and biological features of malaria among <5 year-old children in the paediatric department of the national hospital of niamey, niger's main referral hos ...200515703076
[eco-epidemiology of malaria in niamey and in the river valley, the republic of niger, 1992-1995].the niger valley is an original ecosystem in the sahelian belt. for more than 25 years it has been affected by dryness and rainfall decreased by more than 30% as compared to the period 1950-1960. moreover the demography has sharply increased and the capital town niamey grew by 10% a year. the niger valley including niamey has about 1 million inhabitants. three sites have been selected to study the status of malaria and its evolution for the last 30 years: niamey, karma 40 km on the n.w. on the r ...19979289261
[the progress of malaria in sahelian eastern niger. an ecological disaster zone].the south eastern part of the republic of niger was ecologically damaged by the dryness since 1971. rainfall decreased by 30 to 40% as compared to 1961-70 and lake chad retreated 100 km to the south. now it does not reach any more the republic of niger. malaria studies have been carried out in urban and suburban places in zinder and in the diffa area at the extreme east. in zinder parasitic indexes (pi) after the rainy season were around 30% to 10% according to the situation of the corner in res ...19979289244
[congenital malaria. parasitological and serological studies in niamey (niger)].congenital malaria is defined as the presence of plasmodium parasites in the erythrocytes of newborns less than seven days old. the aim of this study was to determine the incidence of congenital malaria and its possible clinical consequences. we carried out a prospective survey in niamey, the capital of niger (600,000 inhabitants) from july to september 1993. niamey is in an area of mesoendemic malaria and this period of the year corresponds to the rainy season, when malaria transmission is maxi ...200011022149
efficacy of chloroquine in the treatment of uncomplicated, plasmodium falciparum malaria in niamey, niger, in 2001. 200312662426
[plasmodium falciparum chloroquine and pyrimethamine resistance monitoring network with molecular tools in the niger river valley, republic of niger].plasmodium falciparum resistance to chloroquine first arose in africa 25 years ago. nowadays most of african malaria control programmes have switched their first-line treatment of uncomplicated malaria cases towards artemisinin derivatives combination. after who guidelines, a survey network for malaria treatment resistance has been set up in the niger valley around niamey since december 2004. the association of the niger national malaria control programme with the cermes research center allowed ...200818432008
intrarectal quinimax (an association of cinchona alkaloids) for the treatment of plasmodium falciparum malaria in children in niger: efficacy and pharmacokinetics.in an attempt to avoid the complications associated with intramuscular quinine administration, we assessed the intrarectal route. sixty-six children aged from 2 to 10 years with plasmodium falciparum malaria were included in the study, which took place in niamey, niger. fifty-five children were given 20 mg/kg of the diluted injectable form of quinimax (a quinine, quinidine, cinchonine, cinchonidine association) intrarectally. a further 11 children with malaria were treated with 12.5 mg/kg of the ...19957570885
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