| anopheles dirus and its role in malaria transmission in myanmar. | anopheles dirus is one of the primary vectors of highly drug-resistant plasmodium falciparum, which causes cerebral malaria resulting in high mortality. mosquito collections were conducted in a forest wood-extraction area (bago division), an irrigated plain area near foothills (mandalay division), a coastal plain (from domestic wells in the mudon area, mon state) near the foothill area, as well as a hilly area (deep forest timber extraction camp, tanintharyi division) from may 1998 to march 2000 ... | 2003 | 14714666 |
| comparison of the antibody responses to plasmodium vivax and plasmodium falciparum antigens in residents of mandalay, myanmar. | abstract: | 2011 | 21819610 |
| genetic polymorphism of merozoite surface protein-1 and merozoite surface protein-2 in plasmodium falciparum field isolates from myanmar. | merozoite surface protein-1 (msp-1) and msp-2 of plasmodium falciparum are potential vaccine candidate antigens for malaria vaccine development. however, extensive genetic polymorphism of the antigens in field isolates of p. falciparum represents a major obstacle for the development of an effective vaccine. in this study, genetic polymorphism of msp-1 and msp-2 among p. falciparum field isolates from myanmar was analysed. | 2010 | 20478015 |
| genetic variations of the dihydrofolate reductase gene of plasmodium vivax in mandalay division, myanmar. | dihydrofolate reductase (dhfr; ec1.5.1.3) is a known target enzyme for antifolate agents, which are used as alternative chemotherapeutics for chloroquine-resistant malaria. mutations in the dhfr gene of plasmodium vivax are thought to be associated with resistance to the antifolate drugs. in this study, we have analyzed genetic variations in the dhfr genes of clinical isolates of p. vivax (n=21) in myanmar, to monitor antifolate resistance in this country. sequence variations within the entire d ... | 2005 | 15924223 |
| the use of primaquine in malaria infected patients with red cell glucose-6-phosphate dehydrogenase (g6pd) deficiency in myanmar. | 32 subjects with plasmodium falciparum gametocytes, and 31 cases with plasmodium vivax infection from two military hospitals (lashio, mandalay) were treated with quinine 600 mg three times a day for 7 days followed by primaquine 45 mg single dose for gametocytes and 45 mg weekly x 8 weeks for vivax malaria. although screening of red cell glucose-6-phosphate dehydrogenase (g6pd) was done prior to primaquine treatment, g6pd deficient subjects were not excluded from the trial. 20 patients hemizygou ... | 1994 | 7667719 |