| chloroquine resistant plasmodium falciparum malaria in rajasthan. | chloroquine resistance in plasmodium falciparum (pf) malaria in four districts of rajasthan, viz dungarpur, banswara, udaipur and kota, is reported. in vivo sensitivity of pf to chloroquine base 25 mg/kg/body weight over three days was evaluated as per standard who method. a total of 3112 blood smears were collected and examined; 279 cases were selected but only 98 completed the study. twenty four per cent of cases were sensitive, and 54% resistant at ri, 4% at rii and 9% at riii levels. eight p ... | 1991 | 1816220 |
| high prevalence of chloroquine resistant plasmodium falciparum infection in rajasthan epidemic. | plasmodium falciparum is the main killer among all human malaria parasites. in 1994, there was a falciparum malaria epidemic in rajasthan, india, with many deaths. we have investigated active falciparum malaria cases from this epidemic and found that most of the parasite isolates (95%) were resistant to chloroquine. nevertheless, all the tested isolates from the epidemic, were sensitive to mefloquine and quinine and ninety percent were also susceptible to sulfadoxine/pyrimethamine. most individu ... | 1996 | 9025981 |
| studies on malaria transmission in two selected villages in alwar, rajasthan. | | 1979 | 398343 |
| a case series of splenic infarction during acute malaria in northwest rajasthan, india. | malaria is a rare cause of splenic infarction. only a few cases have been reported worldwide, mostly associated with plasmodium falciparum infection. here we report a series of four acute malaria patients with splenic infarction, two with p. vivax infection, one with p. falciparum and one with a mixed infection (p. vivax and p. falciparum). this small case series suggests that if a patient with malaria is complaining of left upper quadrant abdominal pain, pleuritic left lower chest pain and/or e ... | 2010 | 19709707 |
| low efficacy of chloroquine: time to switchover to artemisinin-based combination therapy for falciparum malaria in india. | drug resistance in plasmodium falciparum poses a major threat to malaria control globally; including india. chloroquine is still the most widely used drug in the country because of its safety and cost effectiveness. although chloroquine resistance was first reported in 1973 in north eastern india, the extent of the problem was realized only after the more intensive 28-day drug efficacy studies were used to monitor drug resistance. in the present study, efficacy of chloroquine in treatment of unc ... | 2009 | 19426658 |
| the changing spectrum of severe falciparum malaria: a clinical study from bikaner (northwest india). | recently there were reports from all over india about changing spectrum of clinical presentation of severe malaria. the present study was planned to study the same in the northwest india. | 2006 | 17024858 |
| malaria outbreak in the indira gandhi nahar pariyojna command area in jaisalmer district, thar desert, india. | a focal outbreak of malaria occurred in the villages situated close to the main indira gandhi canal near ramgarh in jaisalmer district, western rajasthan. stagnation of water over a month's period in the main canal as well as long standing rain water in the form of expansive lakes near these villages formed vast breeding grounds for the vectors like anopheles culicifacies, along with a. stephensi already breeding in the 'tanka' and 'beri' in the epidemichit villages. rapid mass blood surveys alo ... | 2001 | 12170943 |
| serological investigation of malaria outbreak in thar desert of rajasthan. | a serological investigation by a repeat cross-sectional survey was conducted in thar desert (rajasthan) during and after one year of malaria outbreak to determine malaria endemicity using elisa as a tool. the assay was based on indirect elisa to measure antibody levels against a nonapeptide r1 (eenvehda-cys) derived from pf 155/resa and plasmodium falciparum crude antigen. finger prick blood samples were collected from individuals belonging to all age groups. sera were tested at already standard ... | 2000 | 11198397 |
| some aspects of changing behaviour of malaria vectors in tribal areas of india. | the field entomological studies and surveys carried out in 72 tribal districts out of 100 in seven penninsular states namely, andhra pradesh, bihar, gujarat, madhya pradesh, maharashtra, orissa and rajasthan indicated that in most of the areas the vector mosquitoes encountered during the present study were almost the same as recorded by the earlier workers except that anopheles fluviatilis james, 1902 was recorded in the areas of district raipur, durg, bilaspur, raigarh, shahdol, rajnandgaon, ba ... | 1998 | 10810568 |
| genetic polymorphism of falciparum malaria vaccine candidate antigen genes among field isolates in india. | the present study was designed to investigate the genetic diversity of plasmodium falciparum among field isolates from india. a total of 71 clinical isolates were analyzed by the polymerase chain reaction (pcr) for the amplification of repeat regions of malaria vaccine candidate antigen genes, i.e., merozoite surface antigen-1 (msa-1), msa-2, and circumsporozoite protein (csp). all three genes showed variation; msa-2 has the maximum number of 10 variant forms while msa-1 and csp had 8 and 6 vari ... | 1999 | 10432065 |
| severe and complicated malaria in bikaner (rajasthan), western india. | severe and complicated malaria is an important cause of mortality in plasmodium falciparum infection. we describe in this study the details of 532 cases of such syndromes admitted to hospital during an outbreak of malaria between september-december 1994. increase in the annual rain fall, collection of water around indra gandhi canal, forestation of shrubs around it and migration of labor, adaptation of anopheles stephensi to desert climate and favorable breeding of an. culicifacies in the areas ... | 1997 | 9444003 |
| correlation of rainfall with upsurge of malaria in rajasthan. | there has been a recent increase in malaria cases in rajasthan. to determine whether environmental factors such as rainfall explain the upsurge we performed a study correlating the amount and duration of rainfall with annual malaria incidence. data of annual incidence of malaria and plasmodium falciparum malaria, annual and monthly rainfall and cultivated land area in rajasthan were acquired from government sources from 1980 to 1994. the mean annual malaria incidence was 277 +/- 90 cases/100,000 ... | 1996 | 9282557 |
| delayed cerebellar ataxia--a complication of plasmodium falciparum malaria. | cerebellar ataxia is an unusual post malarial complication. we encountered 10 patients of this disease (3 in 1992 and 7 in 1994) during the malaria epidemic period in bikaner, rajasthan. all patients were permanent residents to malaria endemic areas. the ataxic symptoms appeared after an afebrile period of 2-7 days. the neurological examination revealed no other abnormality except a cerebellar syndrome interfering with normal gait and speech. lower limbs were affected more than the upper limbs a ... | 1996 | 9251340 |
| status of plasmodium falciparum resistance to chloroquine in gujarat, rajasthan and maharashtra states of india. | an extended study from 1978-88 revealed that in the western states of india i.e., rajasthan, gujarat and maharashtra; p. falciparum resistance to chloroquine has a scattered pattern in its distribution. however in gujarat, r-iii level of resistance is established in southern districts showing four fold increase from 1.79% in 1985 to 8.2% in 1988. in this area use of some alternate drug is indicated. | 1990 | 2209926 |
| knowledge, attitude and practice towards malaria in rural communities of the epidemic-prone thar desert, northwestern india. | in order to assess the knowledge, attitude and practice of the rural thar desert population about malaria and its vectors, a total of 345 heads of households, including housewives, suffering with malaria were surveyed randomly, along with the same number of healthy control subjects, in four villages of jodhpur and jaisalmer districts of rajasthan, north-western india. results showed that in the traditionally hypoendemic thar desert, with low levels of immunity against malaria particularly plasmo ... | 1999 | 10810601 |
| spring transmission of malaria in alwar region (rajasthan). | | 1982 | 6759566 |
| allelic forms of the knob associated histidine-rich protein gene of plasmodium falciparum. | the knob associated histidine-rich protein (kahrp) gene was cloned and sequenced from two indian isolates of plasmodium falciparum, pf3-92 and pf29-92. these isolates showed major sequence differences in the c-terminal repeat domain of kahrp. however, the biologically important domains such as spectrin-actin binding region remained highly conserved. the pcr amplification of a variable c-terminal repeat domain from the clinical isolates of p. falciparum, from rajasthan epidemic, showed the presen ... | 1996 | 8603725 |