Publications

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tularemia transmitted by insect bites--wyoming, 2001-2003.tularemia is a zoonotic disease caused by francisella tularensis, a fastidious, gram-negative coccobacillus that infects vertebrates, especially rabbits and rodents. in humans, tularemia is classified into six major syndromes: ulceroglandular (the most common form), glandular, typhoidal, oculoglandular, oropharyngeal, and pneumonic. the case-fatality rate among humans can reach 30%-60% in untreated typhoidal cases. although bites from ticks and handling infected animals are considered the most c ...200515729218
the serologic prevalence of q fever (coxiella burnetii) complement-fixing antibodies in the peninsular bighorn sheep of southern california.q fever is a rare illness in the southern california desert. during the past 34 years only 6 patients have been diagnosed with the disease at the eisenhower medical center, a referral center for much of the desert and surrounding mountains. in all but 2 instances, q fever was identified in patients who have been in contact with imported domestic sheep who are brought to the desert to graze and lamb in the fall and winter. the sheep are sent back to idaho, wyoming, and montana in the spring. with ...200616896140
population cycles are highly correlated over long time series and large spatial scales in two unrelated species: greater sage-grouse and cottontail rabbits.animal species across multiple taxa demonstrate multi-annual population cycles, which have long been of interest to ecologists. correlated population cycles between species that do not share a predator-prey relationship are particularly intriguing and challenging to explain. we investigated annual population trends of greater sage-grouse (centrocercus urophasianus) and cottontail rabbits (sylvilagus sp.) across wyoming to explore the possibility of correlations between unrelated species, over mu ...201120848136
Structural and Functional Properties of Glycerol-3-Phosphate Dehydrogenase from a Mammalian Hibernator.Glycerol-3-phosphate dehydrogenase (G3PDH; E.C.1.1.1.8) was purified from liver and skeletal muscle of black-tailed prairie dogs (Cynomys ludivicianus), a hibernating species. Native and subunit molecular masses of the dimeric enzyme were 77 and 40 kD, respectively, and both tissues contained a single isozyme with a pI of 6.4. Kinetic parameters of purified G3PDH from prairie dog liver and muscle were characterized at 22 and 5 °C and compared with rabbit muscle G3PDH. Substrate affinities for hi ...201122180227
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