Publications

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the 1976 paul b. beeson lecture. some observations on experimental endocarditis. 1977322401
the research animal and the significance of a health monitoring program.the criteria for the selection of stocks and strains of laboratory animals were discussed. these include metabolic and environmental factors as well as the presence or introduction of infectious agents. the investigator is now concerned with his experimental animals from conception to death, not just during an experiment. the basis of a health monitoring program to ascertain the health status of incoming animals, to evaluate the status of the environment, and to document the ongoing status of a ...1976818449
spirochetes in ticks and antibodies to borrelia burgdorferi in white-tailed deer from connecticut, new york state, and north carolina.ticks were screened for spirochetes and serum samples from white-tailed deer (odocoileus virginianus) were assayed for antibodies to borrelia burgdorferi during 1983-1984. using fluorescein isothiocyanate-labeled rabbit antibodies produced to b. burgdorferi, the etiologic agent of lyme disease, spirochetes were detected in ixodes dammini (10.5% of 1,193) and dermacentor albipictus (0.6% of 157) adults from connecticut, i. dammini nymphs (49.1% of 108) and adults (64.7% of 99) from armonk, new yo ...19863520030
borreliosis in dogs from southern connecticut.blood samples were obtained from dogs in tick-infested regions of southern connecticut to assess canine exposure to borrelia burgdorferi, the etiologic agent of lyme disease in human beings. an indirect fluorescent antibody test detected immunoglobulin (ig)m antibodies at titers of 1:64 to 1:512 in 22 of 84 serum samples previously shown to be positive with a polyvalent rabbit anti-dog total ig conjugate. analyses of paired serum samples from 20 seropositive dogs revealed temporal differences in ...19853997647
human dermal myiasis caused by rabbit bot fly in connecticut. 19705468177
the discovery of erythropoietin.a personal vignette of life as a resident and fellow at the yale new haven hospital in the early 1950s follows. john peters and his associates created a superb renal center at yale new haven, and they instilled in me a respect for quantitative measurements and a love for simple physiologic concepts. the environment was ideal for clinical and laboratory research, and it enabled me to show the existence of a regulatory erythropoietic hormone. i consider it a tribute to dr. peters that erythropoiet ...19938324267
analyses of mammalian sera in enzyme-linked immunosorbent assays with different strains of borrelia burgdorferi sensu lato.blood samples were collected from cottontail rabbits (sylvilagus floridanus), raccoons (procyon lotor), white-footed mice (peromyscus leucopus), and white-tailed deer (odocoileus virginianus) between 1977 and 1991 in southern connecticut and new york state (usa) and were tested for antibodies against eight strains of borrelia burgdorferi sensu lato in enzyme-linked immunosorbent assays. among these spirochetes were six strains of b. burgdorferi sensu stricto, one strain of b. garinii (=ip90) and ...19958583632
from tryptophan to hydroxytryptophan: reflections on a busy life.given the very difficult odyssey of my early years, who could have imagined the incredible and successful journey that constituted my life path after age 13? i was born into a jewish family in breslau, germany, right before the rise of nazism and hitler's election. after kristallnacht, when my father was taken to buchenwald concentration camp, we had to leave germany as soon as possible. the first opportunity came in may of 1939, when we boarded the ss st. louis bound for havana, cuba. almost al ...200919400702
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