the association of aluminum alzheimer's disease, and neurofibrillary tangles. | alzheimer's disease is a progressive neurodegenerative disease characterized by the development of large numbers of neurofibrillary tangles in certain neuronal populations. aluminum salts inoculated into experimental animals produce neurofilamentous lesions which are similar, but not identical, to the neurofibrillary tangle of alzheimer's disease. although a few reports suggest evidence of increased amounts of aluminum in the brains of alzheimer's disease victims, such bulk analysis studies have ... | 1987 | 3316495 |
brain amyloid in normal aging and cerebral amyloid angiopathy is antigenically related to alzheimer's disease beta-protein. | amyloid deposition is a prominent feature of a number of brain disorders, in which amyloid fibrils are found within blood vessel walls, the neuropil (neuritic plaques), neurons (neurofibrillary tangles). these include alzheimer's disease (ad), ad changes associated with down's syndrome, neurologically asymptomatic amyloidosis, parkinson dementia of guam, hereditary cerebral hemorrhage with amyloidosis of icelandic origin (hchwa-i), hereditary cerebral hemorrhage with amyloidosis of dutch origin ... | 1987 | 3322021 |
[morphological, morphometrical and metal analysis studies of oral aluminum neurotoxicity]. | environmental factor is noteworthy for pathogenesis of als. yase reported low contents of ca, mg and high contents of al, mn in environmental samples (soil and water) obtained from kii peninsula and guam where als has been occurring in high incidence. in this paper, to evaluate the role of these environmental factors for degeneration of als, morphological, morphometrical and metal analytical studies on experimental animals will be described with special attention to the neurotoxicity of oral adm ... | 1987 | 3675927 |