coagulant thrombin-like enzymes from the venoms of brazilian and peruvian bushmaster (lachesis muta muta) snakes. | two isoforms of a thrombin-like enzyme designated tle-b and tle-p were purified from the venoms of lachesis muta muta (bushmaster) snakes captured in two different geographical localities, manaus (brazil) and pucallpa (perú). tle-b and tle-p showed mr values of 44000 and 43000 under reducing conditions on sds-page, which decreased to 27000 after deglycosylation with n-glycosidase f (pngase f). the purified proteinases split off fibrinopeptide a rapidly from human fibrinogen and fibrinopeptide b ... | 2003 | 14529751 |