| chagas' disease and the involvement of the autonomic nervous system. | chagas' disease is a major endemic disease in latin america and a great cause for concern due to its high incidence: it afflicts 16 to 18 million individuals and places over 90 million people at risk of infection. at present, five mechanisms can be proposed to explain the pathogenesis of chronic chagas cardiopathy: 1. direct lesion of the tissue by trypanosoma cruzi; 2. dysfunction of the autonomic nervous system (neurogenic concept); 3. microvascular disease; 4. immunologic reaction; 5. alterat ... | 2003 | 14526698 |