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effects of dobutamine and terbutaline on adenylate cyclase activity and cyclic amp content in the renal pelvis of rabbits.we measured the adenylate cyclase activity and the cyclic amp content of the upper and lower renal pelvis in rabbits in order to clarify whether cyclic amp acted as the intracellular messenger of the response elicited by beta-agonists in renal pelvic smooth muscle. adenylate cyclase activity was determined by the method of salomon et al. and tissue cyclic amp content by radioimmunoassay. dobutamine elevated the adenylate cyclase activities and tissue cyclic amp contents of the upper part of the ...19921334605
verification of htlv-i infection in the solomon islands by virus isolation and gene amplification.we report the detection of human t-lymphotropic virus type i (htlv-i) genomic sequences by polymerase chain reaction in lymphocyte cultures of three unrelated native solomon islanders, including a patient with htlv-i myeloneuropathy, residing in widely separated regions. in addition, we have isolated htlv-i from t-cell lines derived from two of these individuals. virus-specific proteins of 15, 19, 24, 46 and 53 kilodaltons were detected by immunofluorescence and western immunoblot, using serum f ...19911902446
effect of dobutamine on adenylate cyclase activity in rabbit renal pelvis and ureter.the adenylate cyclase activity in the rabbit renal pelvis and ureter was measured by the method of salomon et al. (1974). the dobutamine-induced increase of adenylate cyclase activity is more prominent in the renal pelvis including the pacemaker region than in the ureter that is non-pacemaker region in the upper urinary tract. therefore, it is thought that the pacemaker region is different from other regions in the upper urinary tract with regard to responses to dobutamine.19863705060
[effects of prostaglandin e1, e2 and f2 alpha on the changes in the adenylate cyclase activities of rabbit urinary tract tissues].effects of prostaglandin e1, e2 and f2 alpha (pge1, pge2 and pgf2 alpha) on the changes in the adenylate cyclase (ac) activities of rabbit urinary tract tissues were studied in order to clarify whether the pgs' actions are mediated by camp in the urinary tract. ac activities were measured by the method of salomon et al. the three pgs studied were all found to increase the ac activities dose-dependently in the renal pelvis, ureter, bladder dome and bladder base. among the changes in ac activities ...19938389621
a novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor cd36 and is enriched in atherosclerotic lesions.the macrophage scavenger receptor cd36 plays an important role in binding and uptake of oxidized forms of low-density lipoprotein (ldl), foam cell formation, and lesion development during atherosclerosis. the structural basis of cd36-lipoprotein ligand recognition is an area of intense interest. in a companion article we reported the characterization of a structurally conserved family of oxidized choline glycerophospholipids (oxpc(cd36)) that serve as novel high affinity ligands for cells stably ...200212145296
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