| moderate reduction of beta-globin gene transcript by a novel mutation in the 5' untranslated region: a study of its interaction with other genotypes in two families. | we have identified two individuals of greek cypriot origin with thalassemia intermedia. molecular analysis has shown that each individual is a compound heterozygote for a previously described beta zero thalassemia allele and a novel mutation, c-->g in position +33, in the 5' untranslated region of the beta globin gene. in both families the beta +33 allele is associated with the same beta haplotype (-++- ) suggesting that it is likely to be of a single origin, beta-cdnas from normal and mutant be ... | 1996 | 8562944 |
| hypoglycemic activity of salvia fruticosa mill. from cyprus. | salvia fruticosa mill. has a folk reputation in the eastern mediterranean region as a hypoglycemic agent. in order to confirm this claim, a 10% infusion of its leaves was tested, at an oral dose of 0.250 g/kg b.w.t., on normoglycemic rabbits and in rabbits made hyperglycemic by alloxan administration. this oral dose caused a statistically significant reduction in blood glucose levels in alloxanhyperglycemic rabbits, but not in normoglycemic animals, only after repeated administrations of the inf ... | 1991 | 1795516 |