Publications

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thirteen british cases of erythema chronicum migrans, a spirochaetal disease.thirteen british cases of erythema chronicum migrans are reported. an antibody to the lyme disease spirochaete was found in three of five recent cases, but lyme disease was not seen. the distribution and life cycle of the tick ixodes ricinus is described and related to the occurrence of erythema chronicum migrans in great britain.19846477830
evidence for the transmission of the lyme disease spirochaete to sheep in cumbria. 19947831744
distribution of borrelia burgdorferi s.l. spirochaete dna in british ticks (argasidae and ixodidae) since the 19th century, assessed by pcr.the distribution of borrelia burgdorferi sensu lato, the lyme borreliosis agent, was surveyed in british ticks in the collection of the natural history museum, london. alcohol-preserved specimens of eight species of ticks known to attack humans were studied: ixodes ricinus, i. hexagonus, i. uriae, i. trianguliceps, dermacentor reticulatus, haemaphysalis punctata, rhipicephalus sanguineus and argas vespertilionis. the sample comprised all life stages and originated from a wide range of host speci ...19989513944
dark-field microscopy of subgingival plaque microflora in indian and english subjects.this present investigation reports on the microbial pattern of subgingival plaque from english and indian subjects living in the west midlands of england. subgingival plaque from healthy and diseased sites was studied using darkfield microscopy. the results indicate that significant differences exist in microbial flora of clinically normal and diseased sites of english as well as indian subjects. coccoid cells predominated in healthy sites, with an increase of 21% in the spirochaetes in diseased ...19883198777
host migration impacts on the phylogeography of lyme borreliosis spirochaete species in europe.the geographic patterns of transmission opportunities of vector-borne zoonoses are determined by a complex interplay between the migration patterns of the host and the vector. here we examine the impact of host migration on the spread of a tick-borne zoonotic disease, using lyme borreliosis (lb) spirochaetal species in europe. we demonstrate that the migration of the lb species is dependent on and limited by the migration of their respective hosts. we note that populations of borrelia spp. assoc ...201120722696
should we routinely screen for lyme disease in patients with asymmetrical hearing loss?asymmetrical sensorineural hearing loss is usually investigated thoroughly but a diagnosis is often elusive. it is important to identify any treatable causes. lyme disease is a tick-borne infection caused by the spirochaete borrelia burgdorferi, which has been shown to cause asymmetrical sensorineural hearing loss, and has been successfully treated. its incidence varies regionally; it occurs where there is a suitable environment for the tick and its animal hosts. we conducted a prospective study ...19947841889
isolation and characterisation of intestinal spirochaetes.faeces or rectal swabs from 1527 subjects were examined for the presence of intestinal spirochaetes by anaerobic culture on blood agar incorporating spectinomycin (400 mg/l). twenty three specimens (1.5%) were positive, and only one of these came from a patient with diarrhoea. all positive specimens came from either asians or known homosexuals. comparative tests showed a close phenotypic similarity between the human isolates and non-pathogenic porcine intestinal spirochaetes. these organisms dif ...19863722407
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