antibodies to spotted fever-group rickettsiae in dogs in north carolina. | a seroepidemiologic survey was conducted to determine the prevalence of antibodies reactive with 4 spotted fever-group (sfg) rickettsiae in sera of dogs from various geographic regions in north carolina. serum specimens were obtained from 600 dogs, and antibody titers were determined, using microimmunofluorescence. data analysis (setting as the criterion for a positive result, a rickettsia rickettsii titer greater than or equal to 1:64) overestimated the actual prevalence of canine exposure to t ... | 1987 | 3118744 |
supportive evidence by field testing and laboratory experiment for a new hypothesis of the ecology and pathogenicity of canine blastomycosis. | | 1974 | 4858211 |
comparative development of temperate zone and arctic isolates of trichinella spiralis in the white mouse. | | 1971 | 5090960 |
blastomycosis. an important medical problem in the central united states. | | 1966 | 5953275 |
prevalence and distribution of sarcocystis sp among wild swine of southeastern united states. | digestive techniques revealed sarcocystis sp infection in 62 of 192 (32%) wild swine collected in alabama, arkansas, georgia, louisiana, mississippi, north carolina, south carolina, tennessee, virginia, and west virginia. sarcosporidia were not detected in wild swine of florida and were rarely found in the lower coastal plains of georgia, mississippi, and south carolina. swine from mountainous terrain in north carolina, tennessee, and west virginia and bottomland floodplain regions of alabama, a ... | 1981 | 6799467 |
rocky mountain spotted fever in areas of high and low prevalence: survey for canine antibodies to spotted fever rickettsiae. | antibodies to rickettsia rickettsii were detected by indirect immunofluorescence in sera from 149 of 467 dogs (32%) examined from 4 military installations located in kentucky, north carolina, pennsylvania, and virginia. the prevalence at individual installations ranged from 4.3% at fort knox, ky, to 63.4% at fort bragg, nc. most of the seropositive dogs were in the working and sporting groups of dogs. the difference in antibody prevalence between sexes was not significant. serologic responses we ... | 1982 | 6808878 |
breed susceptibility to parvovirus. | | 1981 | 7335064 |
rabies surveillance in the united states during 1994. | in 1994, 48 states, the district of columbia, and puerto rico reported 8,224 cases of rabies in nonhuman animals and 6 cases in human beings to the centers for disease control and prevention. nearly 93% (7,632 cases) were wild animals, whereas 7% (592 cases) were domestic species. the total number of reported cases decreased 13.4% from that of 1993 (9,498 cases), with most of the decline resulting from 19.2% fewer cases of rabies in raccoons. two previously described epizootics of rabies involvi ... | 1995 | 7493894 |
rabies surveillance in the united states during 1993. | in 1993, 49 states, the district of columbia, and puerto rico reported 9,495 cases of rabies in nonhuman animals and 3 cases in human beings to the centers for disease control and prevention. greater than 93% (8,889 cases) were wild animals, whereas 6.4% (606 cases) were domestic species. the total number of reported cases increased 9.9% over that of 1992 (8,645 cases), with most of the increase resulting from continued spread of rabies in raccoons (37.1% increase in reported cases over 1992). t ... | 1994 | 7744643 |
rabies surveillance in the united states during 1992. | in 1992, 49 states, the district of columbia, and puerto rico reported 8,644 cases of rabies in nonhuman animals and 1 case in a human being to the centers for disease control and prevention. almost 92% (7,912 cases) were wild animals, the largest number of wild animals ever reported, whereas 8.5% (732 cases) were domestic species. the total number of reported cases increased 23.9% over that of 1991 (6,975 cases), with most of the increase resulting from continued spread of rabies in raccoons. t ... | 1993 | 8307825 |
spoilage bacteria of fresh broiler chicken carcasses. | studies were conducted to identify the bacteria responsible for spoilage of fresh broiler chicken carcasses and to characterize the off-odors these bacteria produce. broiler carcasses were collected from processing plants in the northeast georgia area, the southeastern u.s., arkansas, california, and north carolina. the carcasses were allowed to spoil under controlled conditions at 3 c and spoilage bacteria were isolated. each spoilage bacterium was separately inoculated into a sterile chicken s ... | 1995 | 8825595 |
rabies surveillance in the united states during 1995. | in 1995, 49 states, the district of columbia, and puerto rico reported 7,877 cases of rabies in nonhuman animals and 4 cases in human beings to the centers for disease control and prevention. nearly 92% (7,247 cases) were wild animals, whereas 8% (630 cases) were domestic species. the total number of reported cases decreased 4.2% from that of 1994 (8,230 cases). most of the decline was the result of 17.1% fewer reported cases of rabies in raccoons in areas of the northeast, where rabies is now e ... | 1996 | 8960176 |
immunoblot analysis of the immunoglobulin g response to ehrlichia canis in dogs: an international survey. | historically, considerable variation has been reported in the type and severity of clinical and hematologic abnormalities associated with canine ehrlichiosis. because of difficulties associated with the isolation of intracellular monocytic ehrlichia species in tissue culture systems, few e. canis isolates are available for comparative microbiologic studies. to address the issue of potential e. canis antigenic diversity in different regions of the world, dog sera reactive by indirect fluorescent ... | 1997 | 9087922 |
ability of the lyme disease spirochete borrelia burgdorferi to infect rodents and three species of human-biting ticks (blacklegged tick, american dog tick, lone star tick) (acari:ixodidae). | the infectivity of a diverse collection of borrelia burgdorferi strains from north america for mice was determined as a prelude to vector competence experiments with the 3 primary human-biting tick species in the eastern united states (ixodes scapularis say, dermacentor variabilis (say), amblyomma americanum (l.)]. of the 34 b. burgdorferi strains inoculated into mice, 29 were infectious; the exceptions were 5 isolates from texas. vector competence experiments were conducted with 2 strains from ... | 1997 | 9220680 |
the fleas (siphonaptera) of tennessee. | thirty-three species of fleas are recorded from the state of tennessee. new state records are reported for two species, the pulicid fleas euhoplopsyllus glacialis affinis and pulex simulans. two species of fleas with catholic feeding habits appear to be especially widespread and abundant in tennessee. these are the pulicid ctenocephalides felis which parasitizes cats, dogs, humans, opossums, and other medium to large sized mammals, and the hystrichopsyllid ctenophthalmus pseudagyrtes which is as ... | 1997 | 9221734 |
rabies surveillance in the united states during 1996. | in 1996, 49 states, the district of columbia, and puerto rico reported 7,124 cases of rabies in non-human animals and 4 cases in human beings to the centers for disease control and prevention. nearly 92% (6,550 cases) were wild animals, whereas 8% (574 cases) were domestic species. the total number of reported cases decreased 9.6% from that of 1995 (7,881 cases). although much of the decline was the result of fewer reported cases of rabies in raccoons, fewer cases were also reported among most g ... | 1997 | 9412679 |
rabies surveillance in the united states during 1997. | in 1997, 49 states, the district of columbia, and puerto rico reported 8,509 cases of rabies in nonhuman animals and 4 cases in human beings to the centers for disease control and prevention. nearly 93% (7,899) were wild animals, whereas 7% (610) were domestic species. the total number of reported cases increased 19.4% from that of 1996 (7,128 cases). increases were apparent in each of the major species groups, with the exception of cattle. the relative contributions of these groups to the total ... | 1998 | 9861958 |
characterization of lyme disease spirochetes isolated from ticks and vertebrates in north carolina. | borrelia burgdorferi isolates obtained from numerous locations and from different hosts in north carolina, were compared to previously characterized strains of the lyme disease spirochete and other borrelia spp. the spirochete isolates were confirmed to be b. burgdorferi sensu stricto based on immunofluorescence (ifa) using a monoclonal antibody to outer surface protein a (osp a [h5332]) and polymerase chain reaction (pcr) using a species-specific nested primer for a conserved region of the gene ... | 2000 | 10682743 |
relative abundance and species composition of mosquito populations (diptera:culicidae) in a la crosse virus-endemic area in western north carolina. | container surveys were conducted in 5 communities on the cherokee indian reservation, an area of western north carolina endemic for transmission of la crosse (lac) virus, to determine the potential for peridomestic mosquito breeding, the relative abundance of mosquito species, and the standing crop of mosquitoes per residence. eleven species of mosquitoes were collected, but 80.9% of all mosquitoes reared from containers were aedes triseriatus (say). all communities averaged > 6 containers per r ... | 1996 | 8699454 |
fatal animal attacks in north carolina over an 18-year period. | injuries from animals are very common, but fortunately deaths are rare. few studies, however, have evaluated human deaths due to both venomous and nonvenomous animals. utilizing the medical examiner's data base, this study examines deaths due to venomous and nonvenomous wild and domestic animals in north carolina. during 1972-1989, there were 92 deaths reported. seven categories of "type of animal" involved in the attack were developed. deaths were most likely to occur from june through november ... | 1994 | 8074110 |
relative utilization of reptiles and rodents as hosts by immature ixodes scapularis (acari: ixodidae) in the coastal plain of north carolina, usa. | the interaction of immature black-legged ticks, ixodes scapularis, with reptiles and rodents was investigated in various woodland habitats in the coastal plain of north carolina. reptiles were sampled from april 1 to september 30, 1991. no ticks were found on 95 specimens representing 16 species of snakes. ticks were found on 54 (36.7%) of 147 lizards. i. scapularis was the only tick recovered from lizards. some lizards were collected in drift fence traps each month of the study except august. c ... | 1993 | 7628223 |
survey for heartworm, dirofilaria immitis, and dipetalonema reconditum (nematoda:filarioidea) in dogs from virginia and north carolina. | random-source dogs (n = 100) in virginia and north carolina were surveyed for the microfilariae of dirofilaria immitis. microscopic examination of fresh thin-films and modified knott preparations were made. dirofilaria immitis and dipetalonema reconditum were found in 19% and 6% of the animals, respectively. there was no animal that harbored both species. prevalence was significantly higher in north carolina (28.6%) than in virginia (13.6%) (p less than 0.025). mean pcv was significantly lower ( ... | 1982 | 7200339 |
rocky mountain spotted fever in a dog. | | 1982 | 7056658 |
two cases of dipylidiasis (dog tapeworm infection) in children: update on an old problem. | children in households with dogs and cats may become infected with the dog tapeworm more frequently than suspected. because of age-appropriate hand-to-mouth exploration, young infants and toddlers, through contact with fleas on pets, floors, and furnishings, are particularly susceptible. knowledge of the life cycle of this animal parasite and the manner in which children acquire and demonstrate infection can lead to early diagnosis and effective treatment. | 1983 | 6683398 |
an inter-familial outbreak of yersinia enterocolitica enteritis. | | 1973 | 4707420 |
dorsal laminectomy for caudal cervical spondylomyelopathy: postoperative recovery and long-term follow-up in 20 dogs. | to evaluate the postoperative morbidity and long-term outcome of dogs after dorsal laminectomy for caudal cervical spondylomyelopathy (ccsm). | 2002 | 12209412 |
the tail is wagging the dog. | | 1974 | 4521694 |
antibody activity to babesia canis in dogs in north carolina. | sera from 600 dogs from 6 geographic regions of north carolina were analyzed for antibody activity to babesia canis, using an indirect fluorescent antibody test. overall, 3.8% of the dogs had an antibody titer greater than or equal to 1:80, which was considered to be indicative of infection. dogs were more likely to be seropositive if they were housed at humane facilities and were located within areas of the state with a milder climate than were pet animals living within colder regions of north ... | 1987 | 3551697 |
spirochetes in ticks and antibodies to borrelia burgdorferi in white-tailed deer from connecticut, new york state, and north carolina. | ticks were screened for spirochetes and serum samples from white-tailed deer (odocoileus virginianus) were assayed for antibodies to borrelia burgdorferi during 1983-1984. using fluorescein isothiocyanate-labeled rabbit antibodies produced to b. burgdorferi, the etiologic agent of lyme disease, spirochetes were detected in ixodes dammini (10.5% of 1,193) and dermacentor albipictus (0.6% of 157) adults from connecticut, i. dammini nymphs (49.1% of 108) and adults (64.7% of 99) from armonk, new yo ... | 1986 | 3520030 |
immunoblot analysis of immunoglobulin g response to the lyme disease agent (borrelia burgdorferi) in experimentally and naturally exposed dogs. | immunoblots were used to study the immunoglobulin g response to borrelia burgdorferi in experimentally and naturally exposed dogs. adsorption studies confirmed that the antibodies were specific for b. burgdorferi. experimentally exposed dogs were asymptomatic. naturally exposed dogs included both asymptomatic animals and animals showing signs compatible with lyme disease. naturally exposed dogs were from four geographic regions of the country. no differences were detected between immunoblot patt ... | 1988 | 3366860 |
characterization of the major antigenic protein 2 of ehrlichia canis and ehrlichia chaffeensis and its application for serodiagnosis of ehrlichiosis. | canine monocytic ehrlichiosis, caused by ehrlichia canis or ehrlichia chaffeensis, can result in clinical disease in naturally infected animals. coinfections with these agents may be common in certain areas of endemicity. currently, a species-specific method for serological diagnosis of monocytic ehrlichiosis is not available. previously, we developed two indirect enzyme-linked immunosorbent assays (elisas) using the major antigenic protein 2 (map2) of e. chaffeensis and e. canis. in this study, ... | 2003 | 12853379 |
antibodies to borrelia burgdorferi in dogs in north carolina. | an indirect immunofluorescence assay was used to detect antibodies against borrelia burgdorferi in sera from 600 dogs in 1983 and 402 dogs in 1985. in 1983, the overall prevalence rate of dogs with b burgdorferi titers greater than or equal to 1:64 was 3.6%, whereas in 1985, the prevalence rate was 2.7%. an unexplainable higher seroprevalence was detected in 1 group of dogs tested in 1983. these dogs were from the southern coastal plains of north carolina. in the dogs tested in 1985, this region ... | 1988 | 3288020 |
presumed dirofilaria immitis infections from field-collected mosquitoes in north carolina. | | 1986 | 2906971 |
relative suitability of aedes albopictus and aedes aegypti in north carolina to support development of dirofilaria immitis. | the relative suitability of two colonies established from local strains of aedes albopictus (wilmington and rockingham) and a local (raleigh) and laboratory (liverpool) strain of ae. aegypti to support development of dirofilaria immitis was investigated. high levels of mortality occurred 1-2 days after mosquitoes fed on a heavily microfilaremic (28,617 microfilariae/ml) dog but not when mosquitoes were fed on a dog exhibiting a moderate microfilaremia (3,300 microfilariae/ml). at 15-16 days post ... | 1989 | 2584971 |
brutus is making rounds. | brutus made no judgments. he gave only care and devotion. as a visiting "therapist," the doberman pinscher brought joy and activity to nursing homes. | 1991 | 1666879 |
survey for dirofilaria immitis in mecklenburg county, north carolina. | | 1979 | 438038 |
mad dogs, microbes, and other pests. some medical problems in early durham. | | 2001 | 11370317 |
retrospective analysis of axial skeleton osteosarcoma in 22 large-breed dogs. | medical-records of 22 large-breed dogs (>15 kg) with osteosarcoma (osa) of the axial skeleton were reviewed to determine prevalence of metastasis and survival associated with this neoplasm. all dogs were treated with more than 1 mode of therapy including palliative radiation (n = 12), definitive radiation (n = 8), surgery (n = 7), chemotherapy (n = 12), or some combination of these therapies. metastasis was documented in 10 of 22 dogs (46%), and the median survival for all dogs was 137 days. pri ... | 2001 | 11300594 |
canine rocky mountain spotted fever: a retrospective study of 30 cases. | rocky mountain spotted fever (rmsf) was diagnosed in 30 dogs examined at north carolina state university, veterinary teaching hospital between 1984 and 1997. historical, physical examination, and laboratory abnormalities were reviewed. diagnostic criteria included a four-fold rise in antibody titer to rickettsia rickettsii (r. rickettsii) (n=15) or a single r. rickettsii antibody titer of 1:1,024 or greater (n=15; when this initial titer was determined one week or more after the onset of clinica ... | 2001 | 11204476 |
disaster relief management of companion animals affected by the floods of hurricane floyd. | | 2001 | 11201560 |
results of irradiation of infiltrative lipoma in 13 dogs. | thirteen dogs with infiltrative lipomas were treated with cobalt 60 radiation. four of the thirteen dogs also received either whole body (n = 2) or combination local/whole body (n = 2) hyperthermia in conjunction with radiation therapy. cytoreductive surgery was performed prior to radiation in 10 dogs, although only 3 dogs had microscopic disease at the time of radiation therapy. dogs received a total dose of 45.6 gy-63 gy in 2.5-4 gy/fraction on either a monday/wednesday/friday schedule or on a ... | 2000 | 11130800 |
west nile virus activity--united states, august 18-24, 2004. | during august 18-24, a total of 154 cases of human west nile virus (wnv) illness were reported from 18 states (alabama, arizona, california, colorado, connecticut, florida, georgia, illinois, kentucky, minnesota, mississippi, missouri, nevada, new mexico, north carolina, south dakota, tennessee, and wisconsin). | 2004 | 15329654 |
seroprevalence of ehrlichia canis, ehrlichia equi, and ehrlichia risticii in sick dogs from north carolina and virginia. | ehrlichia canis, e. equi, and e. risticii seroprevalence was determined by microimmunofluorescent antibody testing (ifa) in a sequential population of 1,845 sick dogs admitted during a 1-year period to the north carolina state university veterinary teaching hospital. a seroreactor was defined by a reciprocal ifa titer of > or =80 to e. canis, e. equi, or e. risticii antigens. of the 48 ifa seroreactors, 44 dogs were seroreactive to e. canis, 21 to e. equi, and 0 to e. risticii. seventeen dogs re ... | 2000 | 10668817 |
a retrospective study of ehrlichiosis in 62 dogs from north carolina and virginia. | the purpose of this retrospective study is to report the clinical signs, clinicopathological findings, and response to therapy of 62 dogs from north carolina and virginia. ehrlichiosis was diagnosed in all of these dogs, and previous retrospective studies of ehrlichiosis in dogs were used as a basis for comparison. in this study, the clinical signs commonly associated with ehrlichiosis were observed less frequently than in earlier studies, although previously reported laboratory abnormalities we ... | 1999 | 10357108 |
babesia gibsoni infections in dogs from north carolina. | the recognition of canine babesiosis in north carolina caused by babesia gibsoni documents the expansion of the previously reported endemic area of this disease. clinical signs ranged from severe hemolytic anemia and thrombocytopenia to subclinical infections. no infected dogs had traveled to endemic areas. antibabesial treatment failed to eradicate the organism from infected dogs. | 1999 | 10102180 |
west nile virus activity--united states, october 13-19, 2004. | during october 13-19, a total of 200 cases of human west nile virus (wnv) illness were reported from 20 states (arizona, arkansas, california, colorado, illinois, indiana, iowa, kansas, maryland, michigan, mississippi, missouri, nevada, new mexico, north carolina, oklahoma, pennsylvania, south dakota, wisconsin, and wyoming). | 2004 | 15499683 |
the dog as a sentinel for human infection: prevalence of borrelia burgdorferi c6 antibodies in dogs from southeastern and mid-atlantic states. | lyme disease is the most frequently reported human vector-associated disease in the united states. infection occurs after the bite of an ixodid tick that is infected with borrelia burgdorferi. dogs have often been reported to serve as effective sentinel animals to assess the risk of human b. burgdorferi infection. based on published data of human lyme disease case numbers and our clinical impressions, we hypothesized that canine exposure to b. burgdorferi would be lower in north carolina when co ... | 2004 | 15631067 |
outbreak of listeriosis among mexican immigrants as a result of consumption of illicitly produced mexican-style cheese. | in 2000, an outbreak of listeriosis among hispanic persons was identified in winston-salem, north carolina. the objectives of the present study were to identify the source of, strains associated with, and risk factors for listeria monocytogenes infection for patients affected by the outbreak. | 2005 | 15714412 |
granulocytic ehrlichiosis in dogs from north carolina and virginia. | medical records of 3 dogs from north carolina and 3 dogs from virginia with ehrlichial morulae in circulating neutrophils were studied retrospectively. two clinically distinct disease syndromes, including chronic, moderate to severe anemia (n = 3) and polyarthritis (n = 2) were associated with canine granulocytic ehrlichiosis (cge) in these dogs. one dog was clinically healthy, and abnormalities were not detected during physical examination. clinical signs were nonspecific and included fever, le ... | 1998 | 9560760 |
the dog as a sentinel for human infection: prevalence of borrelia burgdorferi c6 antibodies in dogs from southeastern and mid-atlantic states. | lyme disease is the most frequently reported human vector-associated disease in the united states. infection occurs after the bite of an ixodid tick that is infected with borrelia burgdorferi. dogs have often been reported to serve as effective sentinel animals to assess the risk of human b. burgdorferi infection. based on published data of human lyme disease case numbers and our clinical impressions, we hypothesized that canine exposure to b. burgdorferi would be lower in north carolina when co ... | 2005 | 16011425 |
there are at least three genetically distinct small piroplasms from dogs. | the 18s nuclear subunit ribosomal rna (18s rrna) gene of small piroplasms isolated from dogs from okinawa (japan), oklahoma, north carolina, indiana, missouri, and alabama, was isolated and sequenced. phylogenetic analysis of these sequences and comparisons with sequences from other babesia, cytauxzoon, and theileria species revealed that all canine small babesial isolates, with the exception of isolates from california and spain, were placed in a group containing the babesia spp. sensu stricto. ... | 2000 | 11428342 |
pet dogs as sentinels for environmental contamination. | the presence of environmental contaminants in air, water and food may pose significant health risks to the exposed human population. however, problems associated with assessing chronic exposure to low doses of environmental chemicals, multiple exposure routes, diseases with long latency periods, and non-specific health outcomes make it difficult to conduct the appropriate human epidemiologic studies. it may be useful to complement human epidemiology with animal studies. animals monitored or eval ... | 2001 | 11453293 |
"leg the dead dog lie". | | 2001 | 11799932 |
cyclosporine decreases skin lesions and pruritus in dogs with atopic dermatitis: a blinded randomized prednisolone-controlled trial. | during the last decade, oral cyclosporin (csa) has proven to be effective, in randomized controlled trials, for the treatment of atopic dermatitis (ad) in human patients. the purpose of this blinded randomized controlled trial was to test the hypothesis that csa was successful in reducing the gravity of clinical signs of ad in dogs. thirty dogs with nonseasonal ad were randomly allocated to receive an oral solution of either neoral csa (5 mg kg-1) or prednisolone (0.5 mg kg-1) once daily for 6 w ... | 2002 | 11972891 |
causes of uveitis in dogs: 102 cases (1989-2000). | uveitis is one of the most common ocular diseases and one of the most common causes of blindness in dogs. the purpose of this retrospective study was to correlate the signalment, history, clinical signs and ophthalmic findings of dogs with uveitis with the underlying etiology. we conducted a retrospective study of 102 dogs presented to the ncsu-vth from 1989 to 2000 with clinical signs of uveitis. medical records of dogs presented for uveitis were reviewed. dogs were included in the study only i ... | 2002 | 12071865 |
surgical and interventional radiographic treatment of dogs with hepatic arteriovenous fistulae. | to report outcome after surgical and interventional radiographic treatment of hepatic arteriovenous fistulae (havf) in dogs. | 2007 | 17461943 |
results of radiation therapy in 19 dogs with cutaneous mast cell tumor and regional lymph node metastasis. | the records of 19 dogs with cutaneous mast cell tumor and regional lymph node metastasis (who stage 2) were reviewed to determine the efficacy of radiation therapy in this population. dogs with grade i (n = 1), grade ii (n = 16), and grade iii (n = 2) cutaneous mast cell tumor were included in this study. all dogs were treated with a combination of pre-irradiation surgical cytoreduction of the primary tumor, irradiation of the primary tumor and regional lymph node, and oral prednisone. total rad ... | 2002 | 12175005 |
bartonella species in blood of immunocompetent persons with animal and arthropod contact. | using pcr in conjunction with pre-enrichment culture, we detected bartonella henselae and b. vinsonii subspecies berkhoffii in the blood of 14 immunocompetent persons who had frequent animal contact and arthropod exposure. | 2007 | 17553243 |
use of animation-enhanced video clips for teaching abnormal breathing patterns. | the ability to characterize disease of the respiratory tract accurately based on breathing pattern is helpful for the development of differential diagnoses and an efficient diagnostic plan and critical for the stabilization of patients in respiratory distress. veterinary students do not have sufficient clinical experience to observe personally all types of respiratory diseases and their resultant abnormal breathing patterns. we developed a teaching tool, the animated breathing pattern videotape ... | 2003 | 12733099 |
candida spp. urinary tract infections in 13 dogs and seven cats: predisposing factors, treatment, and outcome. | records from 20 animals (13 dogs, seven cats) with candida spp. urinary tract infections were reviewed. six candida spp. were isolated; candida albicans was the most common isolate. concurrent diseases or nonantifungal drugs administered within 1 month of isolation included antibiotics (n=16), corticosteroids (n=6), diabetes mellitus (n=4), nonurogenital neoplasia (n=3), and noncandidal urogenital disease (n=14). all animals had sources of local or systemic immune compromise that likely predispo ... | 2003 | 12755200 |
spinal arachnoid cysts in 17 dogs. | the medical records of 17 dogs diagnosed with spinal arachnoid cysts at north carolina state university veterinary teaching hospital were retrospectively examined to identify trends in signalment, history, neurological status, treatment, and short- and long-term prognosis. the typical case was that of a nonpainful, progressive ataxia frequently characterized by hypermetria and incontinence. cysts typically occurred in the dorsal subarachnoid space at the first to third cervical vertebrae of youn ... | 2003 | 12755201 |
a retrospective analysis of 140 dogs with oral melanoma treated with external beam radiation. | despite the early notion that canine oral malignant melanoma is radioresistant, recent data suggest that external beam radiotherapy is effective in local tumor control. however, optimal fractionation schedules have not been established. the high rate of regional and distant metastasis is another problem that has hindered long-term control. the role of chemotherapy in the management of canine oral melanoma has also not been determined. in this study, data from 140 dogs irradiated at north carolin ... | 2003 | 12816381 |
neighborhood environment, access to places for activity, and leisure-time physical activity in a diverse north carolina population. | to examine associations between perceived neighborhood characteristics, access to places for activity, and leisure-time physical activity. | 2003 | 13677963 |
a clinicopathologic study of heterogeneous and homogeneous dog populations in north carolina. | | 1965 | 14278289 |
persistent urinary tract infections and reinfections in 100 dogs (1989-1999). | a retrospective study was performed of 100 dogs with persistent urinary tract infections (utis) or reinfections presenting to the north carolina state university (raleigh, nc) veterinary teaching hospital between 1989 and 1999. criteria for selection included > or = 2 positive urine cultures within a 6-month period. signalment, presence of predisposing disorders, urinalysis and urine culture results, and treatment strategies were extracted from the medical records. dogs were a median age of 7 ye ... | 2003 | 14529127 |
noninvasive transthoracic temporary cardiac pacing in dogs. | temporary cardiac pacing is used in the emergency treatment of life-threatening bradyarrhythmias and for the support of heart rate and blood pressure of patients with sick sinus syndrome or high-grade atrioventricular (av) block undergoing general anesthesia, typically for permanent pacemaker implantation. we retrospectively evaluated the safety and efficacy of a noninvasive transthoracic external cardiac pacing system in 42 dogs treated for bradyarrhythmias. optimal placement of the patch elect ... | 2003 | 14529132 |
antinuclear antibodies can be detected in dog sera reactive to bartonella vinsonii subsp. berkhoffii, ehrlichia canis, or leishmania infantum antigens. | the presence of antinuclear antibodies (anas) is used to support a clinical diagnosis of systemic lupus erythematosus (sle) in dogs. however, clinicians must interpret the detection of anas with caution, particularly in light of increasing evidence that dogs with known bacterial and protozoal infections can have high ana titers. retrospectively, medical records were reviewed for all dogs that were concurrently tested for antinuclear antigens and bartonella vinsonii (berkhoffii), ehrlichia canis, ... | 2004 | 14765731 |
eleven cases of vesicular cutaneous lupus erythematosus in shetland sheepdogs and rough collies: clinical management and prognosis. | a cutaneous ulcerative disease is recognized to affect the adult shetland sheepdog and rough collie. this has a distinct clinical and histological appearance consistent with a vesicular variant of cutaneous lupus erythematosus (vcle). retrospective information on the clinical outcome and response to therapy was collected from 11 cases of histologically confirmed vcle. in 8/11 dogs the onset of disease was in the summer; in three dogs recrudescence occurred in subsequent summers. in eight dogs th ... | 2004 | 14989704 |
hepatic abscesses in cats: 14 cases (1985-2002). | in this retrospective study, we describe 14 cats diagnosed with hepatic abscesses. the objective of the study was to report the clinical signs, physical examination findings, clinicopathologic findings, and outcomes in affected cats. these findings were then compared with those previously reported in dogs and humans. clinical signs were vague and included anorexia, lethargy, and weight loss. only 23% of cats had fever, whereas 31% were hypothermic. increases in serum activities of alanine aminot ... | 2004 | 15188814 |
prolonged remission after immunosuppressive therapy in six dogs with pemphigus foliaceus. | limited information is available on the long-term outcome of treatment of pemphigus foliaceus in dogs. the purpose of this study is to report that a prolonged remission can occur after discontinuation of immunosuppressive regimens in some animals with this disease. six dogs were diagnosed with pemphigus foliaceus based on suggestive clinical signs and histopathology. these patients were treated either with immunosuppressive doses of oral glucocorticoids or with a combination of oral glucocortico ... | 2004 | 15305932 |
bartonella henselae igg antibodies are prevalent in dogs from southeastern usa. | in contrast to the large body of literature regarding bartonella henselae in humans and cats, there is little information about b. henselae as an infectious agent in dogs. due to the paucity of information regarding the b. henselae serology in dogs, we performed a cross-sectional serosurvey using b. henselae antigen in order to compare the seroprevalence between sick and healthy dogs from the south-eastern usa. ninety-nine sera were collected from clinically healthy dogs. three hundred and one s ... | 2004 | 15369661 |
malignant tumor formation in dogs previously irradiated for acanthomatous epulis. | in this retrospective study of 57 dogs irradiated for oral acanthomatous epulis, 2 (3.5%) dogs developed a second tumor (sarcoma, osteosarcoma) in the radiation treatment field at 5.2 and 8.7 years after the end of radiation therapy. as opposed to previous reports, no second epithelial tumors developed in the radiation treatment field. there is a risk of radiation-induced carcinogenesis, but it appears that it is a relatively low risk and an event that occurs years after radiation therapy. radia ... | 2004 | 15373265 |
comparison of results for serologic testing and a polymerase chain reaction assay to determine the prevalence of stray dogs in eastern tennessee seropositive to ehrlichia canis. | to determine the prevalence of stray dogs in eastern tennessee seropositive to ehrlichia canis and examine the correlation between results for an elisa, indirect immunofluorescent antibody (ifa) test, and polymerase chain reaction (pcr) assay. | 2004 | 15478765 |
exposure to indoor allergens in day-care facilities: results from 2 north carolina counties. | with 63% of us children under 5 years of age in regular child care, day-care facilities could be an important source of exposure to indoor allergens. | 2005 | 15990786 |
geographic distribution of babesiosis among dogs in the united states and association with dog bites: 150 cases (2000-2003). | to identify the geographic distribution of babesiosis among dogs in the united states and determine, for dogs other than american pit bull terriers (apbts), whether infection was associated with a recent dog bite. | 2005 | 16190594 |
host-feeding patterns of aedes albopictus (diptera: culicidae) in relation to availability of human and domestic animals in suburban landscapes of central north carolina. | aedes albopictus (skuse) (diptera: culicidae) is a major nuisance mosquito and a potential arbovirus vector. the host-feeding patterns of ae. albopictus were investigated during the 2002 and 2003 mosquito seasons in suburban neighborhoods in wake county, raleigh, nc. hosts of blood-fed ae. albopictus (n = 1,094) were identified with an indirect enzyme-linked immunosorbent assay, by using antisera made in new zealand white rabbits to the sera of animals that would commonly occur in peridomestic h ... | 2006 | 16739414 |
human and canine pulmonary blastomycosis, north carolina, 2001-2002. | we investigated a cluster of blastomycosis in 8 humans and 4 dogs in a rural north carolina community. delayed diagnosis, difficulty isolating blastomyces dermatitidis in nature, and lack of a sensitive and specific test to assess exposure make outbreaks of this disease difficult to study. | 2006 | 16965704 |
molecular characterization of rickettsia rickettsii infecting dogs and people in north carolina. | rocky mountain spotted fever (rmst) is an important cause of morbidity and mortality in people and dogs in the united states. disease manifestations are strikingly similar in both species, and illness in dogs can precede illness in people. r. rickettsii has been identified as a select agent by the cdc as a category c priority pathogen by the national institute of allergic and infectious diseases because it is amenable to use as a bioterror agent. the clinical and temporal relationship of natural ... | 2006 | 17114748 |
semiautomated finite element mesh generation methods for a long bone. | the objective of this work was to develop and test a semi-automated finite element mesh generation method using computed tomography (ct) image data of a canine radius. the present study employs a direct conversion from ct hounsfield units to elastic moduli. our method attempts to minimize user interaction and eliminate the need for mesh smoothing to produce a model suitable for finite element analysis. validation of the computational model was conducted by loading the ct-imaged canine radius in ... | 2007 | 17207888 |
peta kills animals. | | 2007 | 17479489 |
morphology and correction of distal tibial valgus deformities. | to characterise distal tibial valgus deformities in dogs through physical examination and radiographic evaluation. | 2007 | 17725588 |
impact of population structure on genetic diversity of a potential vaccine target in the canine hookworm (ancylostoma caninum). | ancylostoma caninum is a globally distributed canine parasitic nematode. to test whether positive selection, population structure, or both affect genetic variation at the candidate vaccine target ancylostoma secreted protein 1 (asp-1), we have quantified the genetic variation in a. caninum at asp-1 and a mitochondrial gene, cytochrome oxidase subunit 1 (cox-1), using the statistical population analysis tools found in the snap workbench. the mitochondrial gene cox-1 exhibits moderate diversity wi ... | 2007 | 17918358 |
in vitro cultivation of a newly recognized babesia sp. in dogs in north carolina. | a novel large babesia sp. from an infected dog was cultivated in vitro by microaerophilous stationary phase culture methodology. a primary culture initiated in enriched rpmi-1640 medium supplemented with 40% canine serum and incubated in a 2% oxygen environment supported parasite growth in vitro. subsequent subcultures into enriched hl-1 medium with 20% fetal bovine serum also supported parasite propagation. cultures were successfully introduced to 5% carbon dioxide in air atmosphere at passage ... | 2008 | 18083310 |
characterization of normal tissue complications in 51 dogs undergoing definitive pelvic region irradiation. | our objective was to further characterize the late normal tissue complications developing after definitive irradiation of pelvic region tumors in dogs, and to search for prognostic factors. the medical records of dogs receiving definitive irradiation of the pelvic region between 1987 and 2005 were reviewed. the following criteria were established for inclusion: total dose > or =45 gy, a portion of colon in the primary field, and a minimum of 6 months follow-up. fifty-one dogs were identified. pr ... | 2008 | 18251301 |
demographic, clinical, and radiographic features of bronchiectasis in dogs: 316 cases (1988-2000). | to determine demographic, clinical, and radiographic features of bronchiectasis in dogs. | 2003 | 14664451 |
serosurvey of antibabesia antibodies in stray dogs and american pit bull terriers and american staffordshire terriers from north carolina. | stray dogs (n=359) and kennel dogs (n=149) from north carolina were tested for evidence of antibabesia antibodies. antibabesia antibodies were detected in 21/359 and 22/149 of the stray and kennel dogs, respectively. a total of 57 dogs from both groups were tested for babesiasis by light microscopy and polymerase chain reaction (pcr). babesia deoxyribonucleic acid (dna) was detected in 3/28 of the stray dogs and 14/29 of the kennel dogs. when babesia dna was detected by pcr, the species-specific ... | 2003 | 14736721 |
allergens in household dust and serological indicators of atopy and sensitization in detroit children with history-based evidence of asthma. | background. home exposure to allergens is an important factor in the development of sensitization and subsequent exacerbations of allergic asthma. we investigated linkages among allergen exposure, immunological measurements, and asthma by examining (1) reservoir dust allergen levels in homes, (2) associations between presence of allergens in homes and sensitization status of resident children, and (3) associations between asthma status and total ige, atopy (by phadiatop), and positive allergen-s ... | 2011 | 21827376 |
Detection of tumour necrosis factor-alpha in dogs with lymphoma(*). | Tumour necrosis factor-alpha (TNF-a) production by malignant lymphoblasts has been identified in vitro and in vivo in mice and humans, respectively. The goals of this study were (1) to evaluate a novel single-sample TNF-a assay and (2) to determine whether TNF-a is increased in dogs with lymphoma prior to and following treatment. Canine TNF-a was analysed concurrently using the novel Siemens Immulite® single-sample automated ELISA and the previously validated Quantikine® standard ELISA. Serum fr ... | 2011 | 22077410 |
parasitology and serology of free-ranging coyotes (canis latrans) in north carolina, usa. | coyotes (canis latrans) have expanded recently into the eastern us and can serve as a source of pathogens to domestic dogs (canis lupus familiaris), livestock, and humans. we examined free-ranging coyotes from central north carolina, us, for selected parasites and prevalence of antibodies against viral and bacterial agents. we detected ticks on most (81%) coyotes, with amblyomma americanum detected on 83% of those with ticks. fifteen (47%) coyotes were positive for heartworms (dirofilaria immiti ... | 2015 | 25984773 |
tick-borne diseases in north carolina: is "rickettsia amblyommii" a possible cause of rickettsiosis reported as rocky mountain spotted fever? | cases of rocky mountain spotted fever (rmsf) in north carolina have escalated markedly since 2000. in 2005, we identified a county in the piedmont region with high case numbers of rmsf. we collected ticks and examined them for bacterial pathogens using molecular methods to determine if a novel tick vector or spotted fever group rickettsiae (sfgr) might be emerging. amblyomma americanum, the lone star tick, comprised 99.6% of 6,502 specimens collected in suburban landscapes. in contrast, dermacen ... | 2008 | 18447622 |
potential and actual terrestrial rabies exposures in people and domestic animals, upstate south carolina, 1994-2004: a surveillance study. | although there has been a reduction of rabies in pets and domestic animals during recent decades in the united states, rabies remains enzootic among bats and several species of terrestrial wildlife. spillover transmission of wildlife rabies to domestic animals therefore remains a public health threat | 2009 | 19236696 |
detection of a large unnamed babesia piroplasm originally identified in dogs in north carolina in a dog with no history of travel to that state. | a 12-year-old 46-kg (101.2-lb) sexually intact male labrador retriever was evaluated because of lymphadenomegaly. the dog resided in texas, and its travel history included many southeastern and eastern shore states but not north carolina. | 2009 | 19793016 |
evaluation of routinely collected veterinary and human health data for surveillance of human tick-borne diseases in north carolina. | tick-borne diseases are an important cause of human morbidity in north carolina. this study evaluated the use of routinely collected veterinary hospital and human hospital emergency department (ed) data for earlier signal detection compared with routine reporting of tick-borne diseases to the north carolina division of public health in 2006 and 2007. the early aberration reporting system was used to detect the earliest indication of an increase in number of dogs infested with ticks that were bro ... | 2011 | 20528167 |
assessing the prevalence of hybridization between sympatric canis species surrounding the red wolf (canis rufus) recovery area in north carolina. | predicting spatial patterns of hybridization is important for evolutionary and conservation biology yet are hampered by poor understanding of how hybridizing species can interact. this is especially pertinent in contact zones where hybridizing populations are sympatric. in this study, we examined the extent of red wolf (canis rufus) colonization and introgression where the species contacts a coyote (c. latrans) population in north carolina, usa. we surveyed 22 000 km(2) in the winter of 2008 for ... | 2011 | 21486372 |