| [studies on the strain differences of schistosoma japonicum in the mainland of china. ii. susceptibility of mammalian hosts]. | six species of animals were percutaneously exposed to cercariae obtained from pools of naturally infected snails from different isolates of s. japonicum in the mainland of china as shown in tables 1 and 2. our results indicated that with the exception of rat, all animals under study were permissive host though their worm recovery rates varied with different isolates. the mean prepatent period in different host species were 35.0 +/- 0.8 to 36.4 +/- 1.0 days for anhui isolate; 34.5 +/- 1.2 to 36.4 ... | 1990 | 2099256 |
| [kala-azar in china from 1985 to 1988. advisory committee on parasitic diseases, moph]. | a total of 1,069 newly discovered cases of kala-azar (a few recurrent cases included) is recorded in china during the four year period from 1985 to 1988. the kala-azar patients were found in the provinces and autonomous regions of gansu, sichuan, xinjiang, shaanxi, shanxi, inner-mongolia and shandong. comparing with the 443 cases recorded during the previous 4 years period 1981-1984, significant uprise of the disease is evident, especially in the provinces of gansu and sichuan. in southern gansu ... | 1989 | 2591032 |
| hepatic damage in experimental and clinical paragonimiasis. | the hepatic damage induced by paragonimus skrjabini, and the migration route of this species and that of p. westermani, were investigated in a series of animal experiments and in 34 clinical and four autopsy cases of paragonimiasis. the major symptoms and signs of an unique case reported from sichuan province included hepatic tenderness, disturbance of hepatic functions, remittent fever, and cough with bloody sputum. laparotomy revealed marked adhesions surrounding the liver, spleen and duodenum ... | 1982 | 7149101 |
| an electrophoretic comparison of schistosoma japonicum (trematoda) from different provinces in the people's republic of china suggests the existence of cryptic species. | schistosoma japonicum from the people's republic of china is considered to represent a single species comprising either 1 or 4 'strains'. we conducted an allozyme electrophoretic study to examine the extent of genetic variation in s. japonicum from mainland china. the allelic profiles of s. japonicum from 7 provinces were established at 16 enzyme loci. s. japonicum from sichuan had 3-5 (19-31%) fixed differences compared with those from zhejiang, anhui, jiangxi, hunan, hubei and yunnan, suggesti ... | 1999 | 10581616 |
| [analysis of nuclear dna gene types of leishmania isolates from hilly and plain foci of china]. | to analyse the nuclear dna (ndna) polymorphism of leishmania isolates from hilly and plain foci of china. | 1998 | 12078288 |
| [the epidemic situation of human rabies from 1984 to 2002 and its preventive measures in china]. | to summarize and analyze the epidemic situation of human rabies from 1984 to 2002 in china, and to explore the possible factors causing the increase of cases so as to provide evidence for preventive and control measures. | 2003 | 14575600 |
| epidemiology of alveolar echinococcosis with particular reference to china and europe. | human alveolar echinococcosis (ae), caused by the metacestode of the fox tapeworm echinococcus multilocularis, is the most pathogenic zoonosis in temperate and arctic regions of the northern hemisphere. prospective collection of human cases in some areas and mass screenings using ultrasound imaging and confirmation with serological techniques have markedly improved our knowledge of the epidemiology of the disease in humans during the past two decades. transmission occurs when eggs of the tapewor ... | 2003 | 15027607 |
| [polymorphisms and species specificity of d2s2944 and d1s2134 loci in chinese han population in chengdu]. | to obtain the data of polymorphism distribution of the two str loci d2s2944, d1s2134 in chinese han population in chengdu and evaluate their usefulness in the field of forensic science. | 2004 | 15573761 |
| a canine purgation study and risk factor analysis for echinococcosis in a high endemic region of the tibetan plateau. | the tibetan plateau of western china has been shown to have a very high prevalence of human cystic echinococcosis (ce) caused by echinococcus granulosus and human alveolar echinococcosis (ae) caused by echinococcus multilocularis. the domestic dog is suspected to be the primary definitive host for the transmission of both e. granulosus and e. multilocularis to humans in this locality. a purgation study of 371 dogs in shiqu county, sichuan province during 2002-2003 resulted in an e. multiloculari ... | 2005 | 15619374 |
| economic effects of echinococcosis in a disease-endemic region of the tibetan plateau. | this report attempts to quantify the economic losses due to echinococcus multilocularis and e. granulosus in shiqu county, sichuan, people's republic of china, as well as illustrate the cost effectiveness of dog anthelmintic prophylaxis combined with a sheep and goat vaccination program in terms of disability-adjusted life years (dalys) saved. we evaluated human losses associated with treatment costs and loss of income due to morbidity and mortality, in addition to production losses in livestock ... | 2005 | 16014823 |
| spatial modelling and ecology of echinococcus multilocularis transmission in china. | recent research in central china has suggested that the most likely transmission mechanism for echinococcus multilocularis to humans is via domestic dogs which are allowed to roam freely and hunt (infected) small mammals within areas close to villages or in areas of tented pasture. this assertion has led to the hypothesis that there is a landscape control on transmission risk since the proximity of suitable habitat for susceptible small mammals appears to be the key. we have tested this hypothes ... | 2006 | 16371253 |
| the epidemiology of human trichinellosis in china during 2000-2003. | the endemic foci of trichinellosis continue to be mainly located in the southwestern, the central and northeastern china. the seroepidemiological surveys of t. spiralis infection in humans were carried out in six provinces or municipals (p/m) of china during 2000-2003, the overall seroprevalence was 3.57%. from 2000 to 2003, 17 outbreaks of human trichinellosis, with 828 cases and 11 deaths, were recorded in 8 p/a of china. all of 11 deaths occurred in the southwestern china (1 case in sichuan, ... | 2006 | 16414006 |
| socioeconomic and behavior risk factors of human alveolar echinococcosis in tibetan communities in sichuan, people's republic of china. | data from two cross-sectional investigations on 7,138 subjects were used to explore risk factors of human alveolar echinococcosis (ae) in tibetan communities. the overall human ae prevalence was 3.1% (223 of 7,138), females had a higher prevalence (3.6%, 132 of 3,713) than males (2.7%, 91 of 3,425; p = 0.011), and herdsmen had a higher prevalence (5.2%, 154 of 2,955) than farmers (1.8%, 12 of 661; p < 0.001) and urban populations (2.1%, 49 of 2,360; p < 0.001). age in all populations, number of ... | 2006 | 16687693 |
| [allele frequencies and species specificity of five short tandem repeat loci of chinese han population in chengdu]. | to obtain the data in polymorphism distribution of the five short tandem repeat (str) loci: d18s979, d11s2014, d18s548, d1s1667 and gata164f07 of chinese han population in chengdu, and to evaluate their usefulness in the field of species specificity in forensic science. | 2006 | 17160956 |
| impact of overgrazing on the transmission of echinococcus multilocularis in tibetan pastoral communities of sichuan province, china. | overgrazing was assumed to increase the population density of small mammals that are the intermediate hosts of echinococcus multilocularis, the pathogen of alveolar echinococcosis in the qinghai tibet plateau. this research tested the hypothesis that overgrazing might promote echinococcus multilocularis transmission through increasing populations of small mammal, intermediate hosts in tibetan pastoral communities. | 2007 | 17355829 |
| [cloning of avastin gene of leishmania donovani isolates from sichuan province and its expression in eucaryotic system]. | to clone and express the avastin gene of two leishmania donovani isolates from sichuan province of china. | 2007 | 17633823 |
| a modified coproantigen test used for surveillance of echinococcus spp. in tibetan dogs. | recently an immunological test for echinococcus spp. antigens in dog faeces has been developed. the antigens appear to be carbohydrates, which survive proteolytic digestion and environmental degradation. for elisa a capture antibody is used to capture the antigens, followed by a detection antibody. this paper describes a modification of the test whereby capture and detection antibodies are generated exclusively to the carbohydrate portion of the parasite tegument. faecal extracts were heated to ... | 2007 | 17897785 |
| species identification of human echinococcosis using histopathology and genotyping in northwestern china. | human cystic echinococcosis, caused by infection with the larval stage of echinococcus granulosus, and alveolar echinococcosis, caused by the larval form of e. multilocularis, are known to be important public health problems in western china. echinococcus shiquicus is a new species of echinococcus recently described in wildlife hosts from the eastern tibetan plateau and its infectivity and/or pathogenicity in humans remain unknown. in the current study, parasite tissues from various organs were ... | 2008 | 18396303 |
| [preliminary evaluation on the transmission potential of visceral leishmaniasis after earthquake in wenchuan]. | data of visceral leishmaniasis cases since 2005 were collected through the national infectious disease monitoring system. number of reported cases in 2005, 2006, 2007 and january to june in 2008 was 59, 49, 77 and 30 in sichuan province, and 92, 106, 162 and 83 respectively in gansu province. with an increase of the number of stray dogs and susceptible human population, damage of the medical services including diagnosis and treatment capacity after the earthquake, there might be a strengthened t ... | 2008 | 19160974 |
| echinococcus granulosus infection and options for control of cystic echinococcosis in tibetan communities of western sichuan province, china. | human cystic echinococcosis (ce) is highly endemic in the tibetan regions of sichuan where most families keep guard dogs and where there are considerable numbers of ownerless/stray dogs. strong buddhist beliefs do not allow for elimination of stray dogs, and many strays are actually fed and adopted by households or monasteries. on account of the high altitude (3900-5000 m), pasturage is the major agricultural activity in this area. the harsh mountainous climate often leads to many grazing animal ... | 2009 | 19399162 |
| [study on the natural foci of marmota himalayana plague in sichuan province]. | to explore the existence of natural foci on marmota himalayana plague in sichuan province and to provide basis for prevention and control of the disease. | 2009 | 19957628 |
| grass height and transmission ecology of echinococcus multilocularis in tibetan communities, china. | alveolar echinococcosis is a major zoonosis of public health significance in western china. overgrazing was recently assumed as a potential risk factor for transmission of alveolar echinococcosis. the research was designed to further test the overgrazing hypothesis by investigating how overgrazing influenced the burrow density of intermediate host small mammals and how the burrow density of small mammals was associated with dog echinococcus multilocularis infection. | 2010 | 20137577 |
| role of dog behaviour and environmental fecal contamination in transmission of echinococcus multilocularis in tibetan communities. | on the eastern tibetan plateau region (sichuan province, china) dogs are regarded as important definitive hosts of echinococcus multilocularis. we studied dog spatial behaviour in 4 tibetan villages in order to determine the role of dogs in environmental contamination and their potential interactions with small mammal intermediate hosts. we identified definitive host species and echinococcus spp. infection status of feces collected in the field by pcr methods and analysed the spatial distributio ... | 2011 | 21854704 |
| The prevalence of canine Leishmania infantum infection in Sichuan Province, southwestern China detected by real time PCR. | Visceral leishmaniasis (VL) is endemic in western China, and becoming an important public health concern. Infected dogs are the main reservoir for Leishmania infantum, and a potential sentinel for human VL in endemic areas. In the present study we investigated the prevalence of Leishmania DNA in dogs from Wenchuan, Heishui and Jiuzhaigou County in Sichuan Province, southwestern China, which are important endemic areas of zoonotic VL, detected by real time PCR. The results will help to design con ... | 2011 | 21910882 |
| distribution of the intermediate hosts of echinococcus multilocularis in shiqu county, sichuan, china. | the rodentia and lagomorpha animals are the intermediate hosts of echinococcus multilocularis, their distribution and infection of this parasite may facilitate the infection of definitive hosts such as dogs. the aim of this study was to determine the distribution of the intermediate hosts of echinococcus multilocularis in shiqu county, sichuan, china. | 2011 | 22040488 |
| Seroprevalence of Toxoplasma gondii Infection in Dogs in Sichuan Province, Southwestern China. | Abstract There is a lack of information concerning the prevalence of Toxoplasma gondii infection in dogs from southwestern China. In the present study, serum samples from 314 household dogs were collected from Wenchuan, Heishui, and Jiuzhaigou in Sichuan Province, southwestern China in May and June 2010, and detected T. gondii antibodies by an indirect haemagglutination test (IHA). Antibodies to T. gondii were found in 11 of 314 (3.5%), with IHA titers of 1:64 in 4 dogs, 1:128 in 3, 1:256 in 2 ... | 2011 | 21864132 |
| the prevalence of canine leishmania infantum infection in western china detected by pcr and serological tests. | abstract: | 2011 | 21554677 |
| [establishment of a mouse-lethal model for pandemic h1n1 influenza virus]. | to establish the mouse-lethal model for pandemic h1n1 influenza virus, provide an animal model for studying the pathogenicity and host adaptation of 2009 pandemic h1n1 influenza virus, and find out the key amino acid mutations which may affect viral virulence and replication. a pandemic h1n1 influenza virus strain, a/sichuan/swl1/2009 (h1n1, sc/1) was passaged in mouse lung by 15 cycles with intranasal infection. the passaged viruses were all propagated in mdck cells and sequenced. based on the ... | 2011 | 21528533 |
| analysis of an outbreak of human rabies in 2009 in hanzhong district, shaanxi province, china. | between march and august 2009, there was an outbreak of rabies in both humans and dogs in hanzhong district, shaanxi province, china. about 7300 humans were bitten by dogs and 20 died of rabies due to failure to perform postexposure prophylaxis. the local authorities therefore conducted a dog slaughter campaign. from a random selection of brains of dogs culled in the campaign, 0/27 tested positive for rabies virus by immunofluorescence. of two dogs known to have bitten humans, one was shown to c ... | 2011 | 20491584 |
| [monitoring the microtus fuscus plague epidemic in sichuan province during 2000 - 2008.]. | to analyze the epidemic tendency of microtus fuscus plague during 2000 - 2008 in sichuan province. | 2009 | 20193590 |
| echinococcosis in tibetan populations, western sichuan province, china. | we screened 3,199 people from shiqu county, sichuan province, china, for abdominal echinococcosis (hydatid disease) by portable ultrasound combined with specific serodiagnostic tests. both cystic echinococcosis (ce) (echinococcus granulosus infection) and alveolar echinococcosis (ae) (e. multilocularis) were co-endemic in this area at the highest village prevalence values recorded anywhere in the world: 12.9% were infected with one or the other form (6.8% ce and 6.2% ae). prevalences of both ce ... | 2005 | 16485472 |
| modeling the transmission of echinococcus granulosus and echinococcus multilocularis in dogs for a high endemic region of the tibetan plateau. | echinococcus granulosus and echinococcus multilocularis abundance and prevalence data, for domestic dogs of shiqu county, sichuan province, people's republic of china, were fitted to mathematical models to evaluate transmission parameters. abundance models, assuming the presence and absence of immunity, were fit for both e. granulosus and e. multilocularis using bayesian priors, maximum likelihood, and monte carlo sampling techniques. when the models were compared, using the likelihood ratio tes ... | 2005 | 15710437 |
| investigation of risk factors for development of human hydatidosis among households raising livestock in tibetan areas of western sichuan province. | to identify factors influencing the development of hydatidosis in tibetan areas of western sichuan. | 2001 | 12571995 |
| detection of circulating antigens and antibodies in toxocara canis infection among children in chengdu, china. | in order to determine the seroprevalence of toxocara spp. infection in children from chengdu, we performed an enzyme-linked immunosorbent assay (elisa) and sandwich elisa (s-elisa) with excretory-secretory antigens isolated from second-stage larvae of toxocara canis (tes-ag elisa). the seroprevalences of t. canis antibodies in the children from rural areas, urban districts, and urban districts with recent ascaris lumbricoides infection were 17.7% (59/333), 2.1% (4/186), and 2.6% (1/38), respecti ... | 1999 | 10219304 |
| seasonal pattern of echinococcus re-infection in owned dogs in tibetan communities of sichuan, china and its implications for control. | human cystic echinococcosis (ce) and alveolar echinococcosis (ae) are highly endemic in tibetan communities of sichuan province. previous research in the region indicated that domestic dog was the major source of human infection, and observations indicated that domestic dog could have more access to intermediate hosts of echinococcus spp.: both domestic livestock (ce) viscera and small mammals (ae), in early winter and again in spring. we hypothesized that there would therefore be a significant ... | 2016 | 27377927 |
| reinfection studies of canine echinococcosis and role of dogs in transmission of echinococcus multilocularis in tibetan communities, sichuan, china. | in the eastern tibetan plateau both human cystic and alveolar echinococcosis (ae) caused by infection with echincoccus granulosus or echinococcus multilocularis, respectively are highly endemic. the domestic dog plays a key role in zoonotic transmission in this region. our primary objective was to investigate the role of domestic dogs in maintaining transmission of e. multilocularis in shiqu county, sichuan. a cohort of 281 dogs was followed up over one year after a single treatment with praziqu ... | 2013 | 23985352 |
| epidemiological investigation of asymptomatic dogs withleishmaniainfection in southwestern china where visceral leishmaniasis is intractable. | heishui county, located in northwest sichuan province, southwestern china, is an endemic area of zoonotic visceral leishmaniasis (vl) and is the most intractable area. vl is never destroyed in it. asymptomatic dogs (leishmaniaparasites have been diagnosed but clinically healthy) are considered to be a potential reservoir host in zoonotic vl area, and most can lead to infection of individuals, that is a new challenge for controlling vl in humans. the present study aimed to assess theleishmaniainf ... | 2016 | 28095666 |