| epidemiology of candidemia: 3-year results from the emerging infections and the epidemiology of iowa organisms study. | bloodstream infections due to candida species cause significant morbidity and mortality. surveillance for candidemia is necessary to detect trends in species distribution and antifungal resistance. we performed prospective surveillance for candidemia at 16 hospitals in the state of iowa from 1 july 1998 through 30 june 2001. using u.s. census bureau and iowa hospital association data to estimate a population denominator, we calculated the annual incidence of candidemia in iowa to be 6.0 per 100, ... | 2002 | 11923348 |
| antifungal susceptibilities of candida species causing vulvovaginitis and epidemiology of recurrent cases. | there are limited data regarding the antifungal susceptibility of yeast causing vulvovaginal candidiasis, since cultures are rarely performed. susceptibility testing was performed on vaginal yeast isolates collected from january 1998 to march 2001 from 429 patients with suspected vulvovaginal candidiasis. the charts of 84 patients with multiple positive cultures were reviewed. the 593 yeast isolates were candida albicans (n = 420), candida glabrata (n = 112), candida parapsilosis (n = 30), candi ... | 2005 | 15872235 |
| candidemia surveillance in iowa: emergence of echinocandin resistance. | we performed prospective surveillance for candidemia at 14 iowa hospitals in 2011-2012. a total of 163 episodes were analyzed. candida albicans (n = 69 [42%]) and candida glabrata (n = 58 [36%]) were the most common species. antifungal resistance was uncommon; 9% of c. glabrata were fluconazole resistant, and 5% (3 isolates) were intermediate or resistant to 1 or more of the echinocandins. molecular analyses of the fks1 and fks2 hotspots of the c. glabrata revealed no mutations except in 2 of th ... | 2014 | 24666704 |