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acute childhood bacterial meningitis in luanda, angola.incidence, morbidity and mortality of bacterial meningitis in developing countries are manifold greater than those in the industrialized world. we reviewed retrospectively children with meningitis treated in the paediatric hospital of luanda in 2004. among the 555 children, median age 11.0 months, the leading agents were haemophilus influenzae type b (hib), pneumococcus, and meningococcus in 60%, 24%, and 10%, respectively. the median length of illness before admission was 7 d. 65% had convulsed ...200818622806
picornaviruses in cerebrospinal fluid of children with meningitis in luanda, angola.human enteroviruses are the most common cause of viral meningitis. viral-bacterial interaction may affect the clinical course and outcome of bacterial meningitis. in africa, viruses might be responsible for 14-25% of all meningitis cases. however, only few studies from africa have reported detection of viruses in the cerebrospinal fluid (csf) or mixed viral-bacterial infections of the central nervous system (cns). the aim of the present study was to investigate the presence of picornaviruses in ...201222585725
hearing impairment after childhood bacterial meningitis dependent on etiology in luanda, angola.childhood bacterial meningitis (bm) damages hearing, but the potential of different agents to cause impairment in developing countries is poorly understood. we compared the extent of hearing impairment in bm caused by haemophilus influenzae type b (hib), streptococcus pneumoniae or neisseria meningitidis among children aged 2 months to 13 years in luanda, angola.201526357930
slow initial β-lactam infusion and oral paracetamol to treat childhood bacterial meningitis: a randomised, controlled trial.background: new antimicrobials or adjunctive treatments have not substantially reduced mortality from acute childhood bacterial meningitis. paracetamol seems to have beneficial effects in bacteraemic adults and some experts recommend initial slow β-lactam infusion. we investigated whether these treatments had benefits in children with bacterial meningitis. methods: we did a prospective, double-blind, single-centre study with a two-by-two factorial design in luanda, angola. 723 participants aged ...201121550313
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