Publications

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isolation of rickettsia tsutsugamushi from mammals and chiggers (fam. trombiculidae) in the pescadores islands, taiwan. 1978418538
correlation of chigger abundance with temperature at a hyperendemic focus of scrub typhus. 1976957048
a team approach to a disease survey on an aboriginal island (orchid island, taiwan). iv. mosquitos and chiggers on lan-yü (orchid island), taitung hsien, taiwan. 19744153585
population indices of chiggers (leptotrombidium deliense) and incidence of scrub typhus in chinese military personnel, pescadores islands of taiwan, 1976-77.larval leptotrombidium deliense were recovered from live-trapped suncus murinus, rattus rattus and r. norvegicus captured in the pescadores islands of taiwan during 1976 and 1977. weekly and monthly indices of chigger infestation expressed as a percentage of hosts infested and the number of chiggers per host for s. murinus and rattus spp. were calculated. close correlations were observed between monthly indices of l. deliense measured for s. murinus and rattus spp. and the number of laboratory-c ...19827080163
characterization of orientia tsutsugamushi isolated in taiwan by immunofluorescence and restriction fragment length polymorphism analyses.a total of 10 strains of orientia tsutsugamushi were isolated from field rodents and chiggers in taiwan, and characterized by immunofluorescence analysis with monoclonal antibodies and by restriction fragment length polymorphism analysis of the 56-kilodalton (kda) protein gene. the isolates were divided into two groups consisting of 1 and 9 strains which showed some relation to gilliam and karp type strains, respectively. however, all these isolates possessed characteristics distinct not only fr ...19979170266
molecular detection and characterization of spotted fever group rickettsiae in taiwan.rickettsioses are emerging infectious diseases caused by rickettsiae in association with arthropods. we report the detection of spotted fever group rickettsiae (sfgr) in taiwan using molecular methods. phylogenetic analyses of the 17-kd protein and citrate synthase (glta) genes showed that sfgr twkm01 detected in rhipicephalus haemaphysaloides ticks was most similar to rickettsia rhipicephali. three twkm01 isolates were obtained from three individual r. haemaphysaloides ticks. small, intracellul ...200717984347
phylogenetic analysis of 56-kda type-specific antigen gene of orientia tsutsugamushi isolates in taiwan.scrub typhus is a rickettsial disease transmitted to humans through the bite of chigger mites infected with orientia tsutsugamushi, and is an endemic disease in taiwan. to elucidate the molecular epidemiology of o. tsutsugamushi, the complete open reading frame of the 56-kda type-specific antigen gene sequence of strains isolated from scrub typhus patients were determined and analyzed. a total of 116 isolates of o. tsutsugamushi were successfully isolated from patients infected in diverse geogra ...201020810835
variation within and among host species in engorgement of larval trombiculid mites.we recovered larval trombiculid mites (i.e. chiggers), vectors of scrub typhus, from small mammal hosts in taiwan, and compared the relative degree of engorgement (rde) of the dominant chigger (leptotrombidium imphalum) from different hosts. naturally occurring chiggers recovered from rattus losea and bandicota indica were 1·4x and 1·3x as engorged as those from apodemus agrarius. within each host species, rde was negatively related to chigger loads, but was mostly unrelated to gender or to body ...201020946695
identification of potential hosts and vectors of scrub typhus and tick-borne spotted fever group rickettsiae in eastern taiwan.scrub typhus and tick-borne spotted fever group (sfg) rickettsioses are transmitted by chiggers (larval trombiculid mites) and hard ticks, respectively. we assessed exposure to these disease vectors by extensively sampling both chiggers and ticks and their small mammal hosts in eastern taiwan during 2007 and 2008. the striped field mouse apodemus agrarius pallas (rodentia: muridae) was the most common of the small mammals (36.1% of 1393 captures) and presented the highest rate of infestation wit ...201121223345
genetic typing, based on the 56-kilodalton type-specific antigen gene, of orientia tsutsugamushi strains isolated from chiggers collected from wild-caught rodents in taiwan.orientia tsutsugamushi is the etiological agent of scrub typhus, a mite-borne, febrile illness that occurs in the asia-pacific region. we conducted strain characterization of o. tsutsugamushi isolates from chiggers obtained from rodents based the nucleotide sequence of the 56-kda outer membrane protein gene. with the use of pcr, a total of 68 dna sequences of 56-kda antigen genes were amplified. phylogenetic analysis revealed that there were at least six definable clusters among the 68 isolates: ...201121441323
spatial analysis of scrub typhus infection and its association with environmental and socioeconomic factors in taiwan.we analyzed the spatial distribution of human cases of scrub typhus on the main island of taiwan from 2003 to 2008 and implemented an island-wide survey of scrub typhus vectors (trombiculid chiggers) in 2007 and 2008. the standardized incidence rate 'sir' incorporating inter-district variations in population, gender and age was correlated with environmental and socioeconomic variables. higher incidence and sir rates were clustered in the less developed, mountainous regions of central and eastern ...201121703220
surveillance of potential hosts and vectors of scrub typhus in taiwan.scrub typhus is a lethal infectious disease vectored by larval trombiculid mites (i.e. chiggers) infected with orientia tsutsugamushi (ot) and recent decades have witnessed an emergence of scrub typhus in several countries. identification of chigger species and their vertebrate hosts is fundamental for the assessment of human risks to scrub typhus under environmental changes, but intensive and extensive survey of chiggers and their hosts is still lacking in taiwan.201526626287
a checklist of chigger mites (acari: trombiculidae and leeuwenhökiidae) from taiwan, with descriptions of three new species.scrub typhus is a lethal human disease transmitted by larval trombiculid mites (i.e., chiggers) that have been infected with the rickettsia orientia tsutsugamushi. in total, 21 chigger species are known from taiwan. we update the checklist of chiggers of taiwan based on an intensive survey of shrew and rodent hosts in grasslands and agricultural fields in lowland taiwan, coupled with surveys of forests in one mountainous site and an opportunistic examination of submitted host specimens. three ne ...201526438572
field assessment of orientia tsutsugamushi infection in small mammals and its association with the occurrence of human scrub typhus in taiwan.we conducted an extensive study in taiwan of orientia tsutsugamushi (ot) infection in small wild mammals. field trapping was carried out at six districts in eastern and western taiwan as well as various offshore islands during the period 2006-2010. a total of 1061 specimens representing 11 rodent species were captured. the presence of ot infection was assessed by indirect immunofluorescence assay and polymerase chain reaction assays of 56-kda type-specific antigen gene. the chigger infestation r ...201424361181
cascading effect of economic globalization on human risks of scrub typhus and tick-borne rickettsial diseases.the increase in global travel and trade has facilitated the dissemination of disease vectors. globalization can also indirectly affect vector-borne diseases through the liberalization of cross-border trade, which has far-reaching, worldwide effects on agricultural practices and may in turn influence vectors through the modification of the ecological landscape. while the cascading effect of economic globalization on vector-borne diseases, sometimes acting synergistically with regional agricultura ...201223092017
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